Zobrazeno 1 - 10
of 372
pro vyhledávání: '"M Addo"'
Autor:
Leonie M. Weskamm, Paulina Tarnow, Charlotte Harms, Melanie Huchon, Matthijs P. Raadsen, Monika Friedrich, Laura Rübenacker, Cordula Grüttner, Mariana G. Garcia, Till Koch, Stephan Becker, Gerd Sutter, Edouard Lhomme, Bart L. Haagmans, Anahita Fathi, Sandra M. Blois, Christine Dahlke, Laura Richert, Marylyn M. Addo
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110470- (2024)
Summary: Besides neutralizing antibodies, which are considered an important measure for vaccine immunogenicity, Fc-mediated antibody functions can contribute to antibody-mediated protection. They are strongly influenced by structural antibody propert
Externí odkaz:
https://doaj.org/article/608910de3c4f4ba4ae8af02bb275eee1
Autor:
Claudia Fischer, Edith Willscher, Lisa Paschold, Cornelia Gottschick, Bianca Klee, Sophie Diexer, Lidia Bosurgi, Jochen Dutzmann, Daniel Sedding, Thomas Frese, Matthias Girndt, Jessica I. Hoell, Michael Gekle, Marylyn M. Addo, Julian Schulze zur Wiesch, Rafael Mikolajczyk, Mascha Binder, Christoph Schultheiß
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract The rapid development of safe and effective vaccines helped to prevent severe disease courses after SARS-CoV-2 infection and to mitigate the progression of the COVID-19 pandemic. While there is evidence that vaccination may reduce the risk o
Externí odkaz:
https://doaj.org/article/b2f3270a8f8644e19352f7f9046def1e
Autor:
Leonie Mayer, Leonie M. Weskamm, Anahita Fathi, Maya Kono, Jasmin Heidepriem, Verena Krähling, Sibylle C. Mellinghoff, My Linh Ly, Monika Friedrich, Svenja Hardtke, Saskia Borregaard, Thomas Hesterkamp, Felix F. Loeffler, Asisa Volz, Gerd Sutter, Stephan Becker, Christine Dahlke, Marylyn M. Addo
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract In response to the COVID-19 pandemic, multiple vaccines were developed using platforms such as viral vectors and mRNA technology. Here, we report humoral and cellular immunogenicity data from human phase 1 clinical trials investigating two r
Externí odkaz:
https://doaj.org/article/5b1fea1ceb2340e395b1e673ec685d27
Autor:
Thomas Theo Brehm, Andreas Heyer, Marcel S. Woo, Marlene Fischer, Marc van der Meirschen, Dominic Wichmann, Dominik Jarczak, Kevin Roedl, Stefan Schmiedel, Marylyn M. Addo, Marc Lütgehetmann, Martin Christner, Samuel Huber, Ansgar W. Lohse, Stefan Kluge, Julian Schulze zur Wiesch
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss 11, Pp 1806-1812 (2023)
Background: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, the roll-out of vaccines and therapeutic agents, as well as the emergence of novel SARS-CoV-2 variants, have shown significant effects on disease severity. Methods:
Externí odkaz:
https://doaj.org/article/efa2ba5d37094146a5932b908907dff7
Autor:
Guido Schäfer, Rabea Lübke, Olaf Degen, Maria Mader, Robin Scheiter, Annika Wolski, Marylyn M. Addo, Julian Schulze zur Wiesch, Sven Pischke
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 28, Iss 1, Pp 103720- (2024)
Background: While the sexual transmissibility of HAV in MSM has been extensively described, the potential for sexual transmission of HEV has not been definitively established. Although HEV has been detected in the ejaculate of chronically infected me
Externí odkaz:
https://doaj.org/article/7f9af6d80d944d3aad710f52125e16d4
Autor:
Ivan Odak, Lennart Riemann, Inga Sandrock, Anne Cossmann, Gema Morillas Ramos, Swantje I. Hammerschmidt, Christiane Ritter, Michaela Friedrichsen, Ahmed Hassan, Alexandra Dopfer-Jablonka, Metodi V. Stankov, Leonie M. Weskamm, Marylyn M. Addo, Inga Ravens, Stefanie Willenzon, Anja Schimrock, Jasmin Ristenpart, Anika Janssen, Joana Barros-Martins, Gesine Hansen, Christine Falk, Georg M.N. Behrens, Reinhold Förster
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104947- (2024)
Summary: Background: Human immune responses to COVID-19 vaccines display a large heterogeneity of induced immunity and the underlying immune mechanisms for this remain largely unknown. Methods: Using a systems biology approach, we longitudinally prof
Externí odkaz:
https://doaj.org/article/dc942db6e492430cafa301d2bcc525b7
Autor:
Katrin Hufnagel, Anahita Fathi, Nadine Stroh, Marco Klein, Florian Skwirblies, Ramy Girgis, Christine Dahlke, Jörg D. Hoheisel, Camille Lowy, Ronny Schmidt, Anne Griesbeck, Uta Merle, Marylyn M. Addo, Christoph Schröder
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-13 (2023)
Abstract Background The clinical course of COVID-19 patients ranges from asymptomatic infection, via mild and moderate illness, to severe disease and even fatal outcome. Biomarkers which enable an early prediction of the severity of COVID-19 progress
Externí odkaz:
https://doaj.org/article/a7d8b214bf0e427a9a9595f6ab093930
Autor:
Claudia Beisel, Ana Jordan-Paiz, Sandra Köllmann, Annika Elise Ahrenstorf, Benedetta Padoan, Tanja Barkhausen, Marylyn M. Addo, Marcus Altfeld
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-11 (2023)
Highlights Women showed higher percentage of IRF5 positive B cells compared to men. After stimulation with a TLR7 or TLR9 agonist, women showed higher percentages of IRF5 positive B cells compared with those of men. B cells of women produced higher l
Externí odkaz:
https://doaj.org/article/9579caecbe1c48f2a1758fb8a4398b8b
Autor:
Dominik Nörz, Hui Ting Tang, Petra Emmerich, Katja Giersch, Nicole Fischer, Stephan Schmiedel, Marylyn M. Addo, Martin Aepfelbacher, Susanne Pfefferle, Marc Lütgehetmann
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 9, Pp 1765-1769 (2022)
Beginning in May 2022, a rising number of monkeypox cases were reported in non–monkeypox-endemic countries in the Northern Hemisphere. We adapted 2 published quantitative PCRs for use as a dual-target monkeypox virus test on widely used automated h
Externí odkaz:
https://doaj.org/article/aca478786aa6465baf32eb3092b66b42
Autor:
Anahita Fathi, Christine Dahlke, Verena Krähling, Alexandra Kupke, Nisreen M. A. Okba, Matthijs P. Raadsen, Jasmin Heidepriem, Marcel A. Müller, Grigori Paris, Susan Lassen, Michael Klüver, Asisa Volz, Till Koch, My L. Ly, Monika Friedrich, Robert Fux, Alina Tscherne, Georgia Kalodimou, Stefan Schmiedel, Victor M. Corman, Thomas Hesterkamp, Christian Drosten, Felix F. Loeffler, Bart L. Haagmans, Gerd Sutter, Stephan Becker, Marylyn M. Addo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
In a clinical trial, Fathi et al. show that a booster vaccination with a vector vaccine candidate against the highly pathogenic Middle East Respiratory Syndrome coronavirus is safe and strongly improves the immunity generated by primary immunization.
Externí odkaz:
https://doaj.org/article/9c0741a645df4990aa04ffff02338df4