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pro vyhledávání: '"M A Simon"'
Akademický článek
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We discuss Hamiltonian symmetries and invariants for quantum systems driven by non-Hermitian Hamiltonians. For time-independent Hermitian Hamiltonians, a unitary or antiunitary transformation $AHA^\dagger$ that leaves the Hamiltonian $H$ unchanged re
Externí odkaz:
http://arxiv.org/abs/1805.04968
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-19 (2022)
Abstract Background Deregulated glucose metabolism is a critical component of cancer growth and survival, clinically evident via FDG-PET imaging of enhanced glucose uptake in tumor nodules. Tumor cells utilize glucose in a variety of interconnected b
Externí odkaz:
https://doaj.org/article/d4989391689b406bbb0918335fc7b0c9
Autor:
Sanika Khare, Laura C. Kim, Graham Lobel, Paschalis-Thomas Doulias, Harry Ischiropoulos, Itzhak Nissim, Brian Keith, M. Celeste Simon
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Background Kidney cancer is a common adult malignancy in the USA. Clear cell renal cell carcinoma (ccRCC), the predominant subtype of kidney cancer, is characterized by widespread metabolic changes. Urea metabolism is one such altered pathwa
Externí odkaz:
https://doaj.org/article/c58358261d474004af1c1f7c4c61d199
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Abstract To identify drivers of sarcoma cancer stem-like cells (CSCs), we compared gene expression using RNA sequencing between HT1080 fibrosarcoma and SK-LMS-1 leiomyosarcoma spheroids (which are enriched for CSCs) compared with the parent populatio
Externí odkaz:
https://doaj.org/article/0625113d899f4955a7ef9d844d1be2e3
Autor:
Changhwan Yoon, Jun Lu, Brendan C. Yi, Kevin K. Chang, M. Celeste Simon, Sandra Ryeom, Sam S. Yoon
Publikováno v:
Oncogenesis, Vol 10, Iss 1, Pp 1-14 (2021)
Abstract The self-renewal transcription factor Nanog and the phosphoinositide 3-kinase (PI3K)–Akt pathway are known to be essential for maintenance of mesenchymal stem cells. We evaluated their contribution to the maintenance of CD133(+) cancer ste
Externí odkaz:
https://doaj.org/article/c812dcceff6c415689c86e614ec71d8f
Akademický článek
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Autor:
Mark J. Ranek, Christian Oeing, Rebekah Sanchez-Hodge, Kristen M. Kokkonen-Simon, Danielle Dillard, M. Imran Aslam, Peter P. Rainer, Sumita Mishra, Brittany Dunkerly-Eyring, Ronald J. Holewinski, Cornelia Virus, Huaqun Zhang, Matthew M. Mannion, Vineet Agrawal, Virginia Hahn, Dong I. Lee, Masayuki Sasaki, Jennifer E. Van Eyk, Monte S. Willis, Richard C. Page, Jonathan C. Schisler, David A. Kass
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Carboxyl terminus of Hsc70-interacting protein (CHIP) is proteostasis regulator. Here the authors show that CHIP-mediated protein turnover is enhanced by PKG-mediated phosphorylation, which results in attenuated cardiac ischemic proteotoxicity.
Externí odkaz:
https://doaj.org/article/7e6f8490744a4cef9d24e2c03e23c499
Autor:
Pearl Lee, Dania Malik, Nicholas Perkons, Peiwei Huangyang, Sanika Khare, Seth Rhoades, Yao-Yu Gong, Michelle Burrows, Jennifer M. Finan, Itzhak Nissim, Terence P. F. Gade, Aalim M. Weljie, M. Celeste Simon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Tumour cells frequently utilize glutamine to meet bioenergetic and biosynthetic demands of rapid cell growth. However, glutamine dependence can be highly variable between in vitro and in vivo settings, based on surrounding microenvironments
Externí odkaz:
https://doaj.org/article/3b907274e9ce47de86b2c4ff4f6b6ad0
Autor:
M. H., Simon1,2 (AUTHOR), P. E., Heenan1,3 (AUTHOR), C., Frampton1 (AUTHOR), S., Bayer1,3 (AUTHOR), J. I., Keenan3,4 (AUTHOR), N. K., Boer de2 (AUTHOR), N. C., Roy3,5 (AUTHOR), N. J., Talley6,7 (AUTHOR), R. B., Gearry1,3 (AUTHOR) richard.gearry@cdhb.health.nz
Publikováno v:
Neurogastroenterology & Motility. Jan2023, Vol. 35 Issue 1, p1-9. 9p.