Výsledky vyhledávání - "M A Quinn-Allen"

MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele

Autor: N J Crowley, T L Darrow, M A Quinn-Allen, H F Seigler

Publikováno v: The Journal of Immunology. 146:1692-1699

Autologous melanoma-specific CTL recognize a common tumor-associated Ag (TAA) in the context of HLA class I antigens. We have demonstrated that HLA-A2 can be a restricting Ag and, in T cell lines homozygous for HLA-A2, that CTL can be generated by st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e6978e3f98508b7ebd166efc4a71e05
https://doi.org/10.4049/jimmunol.146.5.1692

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Inhibitory anti-factor V antibodies bind to the factor V C2 domain and are associated with hemorrhagic manifestations

Autor: T L, Ortel, K D, Moore, M A, Quinn-Allen, T, Okamura, A J, Sinclair, J, Lazarchick, R, Govindan, F, Carmagnol, W H, Kane

Publikováno v: Blood. 91(11)

Factor V inhibitors may develop as spontaneous autoantibodies, as alloantibodies after exposure to bovine thrombin preparations, or in factor V-deficient patients after plasma therapy. Clinical manifestations range from asymptomatic laboratory abnorm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a928b4b44ee9f09a558b5c9cf510c90d
https://pubmed.ncbi.nlm.nih.gov/9596666

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Localization of functionally important epitopes within the second C-type domain of coagulation factor V using recombinant chimeras

Autor: T L, Ortel, M A, Quinn-Allen, F G, Keller, J A, Peterson, D, Larocca, W H, Kane

Publikováno v: The Journal of biological chemistry. 269(22)

Coagulation factor V, an integral component of the prothrombinase complex, possesses two C-type domains at the carboxyl-terminal end of the molecule. Homologous C-type domains are present in factor VIII as well as several non-coagulation proteins. De

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1af56caa3e38d025bd779f48643ee728
https://pubmed.ncbi.nlm.nih.gov/7515064

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Human melanoma-mediated inhibition of autologous CD4+ helper tumor-infiltrating lymphocyte growth in vitro

Autor: T L, Darrow, Z, Wahab, M A, Quinn-Allen, H F, Seigler

Publikováno v: Cancer. 69(7)

Tumor-infiltrating lymphocytes (TIL) were isolated from a human melanoma metastatic to the abdomen. The TIL were 99% CD3+ and 99% CD4+ and CD8-. They were dependent on interleukin-2 (IL-2) for growth, as measured in a thymidine uptake assay, and were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c3a7517f19f33afca9bacf30156f0af
https://pubmed.ncbi.nlm.nih.gov/1532342

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