Zobrazeno 1 - 10
of 108
pro vyhledávání: '"M A Levenson"'
Autor:
Sandra Sanchez-Roige, Mariela V. Jennings, Hayley H. A. Thorpe, Jazlene E. Mallari, Lieke C. van der Werf, Sevim B. Bianchi, Yuye Huang, Calvin Lee, Travis T. Mallard, Samuel A. Barnes, Jin Yi Wu, Amanda M. Barkley-Levenson, Ely C. Boussaty, Cedric E. Snethlage, Danielle Schafer, Zeljana Babic, Boyer D. Winters, Katherine E. Watters, Thomas Biederer, andMe Research Team, James Mackillop, David N. Stephens, Sarah L. Elson, Pierre Fontanillas, Jibran Y. Khokhar, Jared W. Young, Abraham A. Palmer
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Impulsivity is a multidimensional heritable phenotype that broadly refers to the tendency to act prematurely and is associated with multiple forms of psychopathology, including substance use disorders. We performed genome-wide association st
Externí odkaz:
https://doaj.org/article/b47ec1bf7cc04d37956dc97a36fdfe9e
Autor:
Amelie Baud, Francesco Paolo Casale, Amanda M. Barkley-Levenson, Nilgoun Farhadi, Charlotte Montillot, Binnaz Yalcin, Jerome Nicod, Abraham A. Palmer, Oliver Stegle
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background The phenotype of an individual can be affected not only by the individual’s own genotypes, known as direct genetic effects (DGE), but also by genotypes of interacting partners, indirect genetic effects (IGE). IGE have been detec
Externí odkaz:
https://doaj.org/article/7556fa8d104f4bc0b543092b964934c8
Publikováno v:
Brain Sciences, Vol 11, Iss 1, p 127 (2021)
Central nervous system (CNS) hyperexcitability is a clinically significant feature of acute ethanol withdrawal. There is evidence for a genetic contribution to withdrawal severity, but specific genetic risk factors have not been identified. The gene
Externí odkaz:
https://doaj.org/article/387d6d0566c94d2fa97d9dd802954422
Autor:
Amanda M. Barkley-Levenson, John C. Crabbe, Angela R. Ozburn, Antonia Savarese, Pamela Metten
Publikováno v:
Alcohol
The High Drinking in the Dark mouse lines (HDID-1 and HDID-2) were selectively bred to achieve high blood ethanol concentrations (BECs) in the Drinking in the Dark (DID) task, a widely used model of binge-like intake of 20% ethanol. There are several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23ecd159e78579a0dddb1ba0f2bbad9
https://doi.org/10.1016/j.alcohol.2021.02.001
https://doi.org/10.1016/j.alcohol.2021.02.001
Autor:
Sandra Sanchez-Roige, Mariela V Jennings, Hayley H A Thorpe, Jazlene E Mallari, Lieke C van der Werf, Sevim B Bianchi, Calvin Lee, Travis T Mallard, Samuel A Barnes, Jin Yi Wu, Amanda M Barkley-Levenson, Ely C Boussaty, Cedric E Snethlage, Danielle Schafer, Zeljana Babic, Boyer D Winters, Katherine E Watters, Thomas Biederer, James Mackillop, David N Stephens, Sarah L Elson, Pierre Fontanillas, Jibran Y Khokhar, Jared W Young, Abraham A Palmer
Impulsivity is a multidimensional heritable phenotype that broadly refers to the tendency to act prematurely and is associated with multiple forms of psychopathology, including substance use disorders. We performed genome-wide association studies (GW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b91e23c15578708c4b5e6be4dd0443b1
https://doi.org/10.1101/2022.01.29.22270095
https://doi.org/10.1101/2022.01.29.22270095
Autor:
Xinzhu Zhou, Patricia Montilla-Perez, Francesca Telese, Amanda M. Barkley-Levenson, Abraham A. Palmer
Publikováno v:
Genes, Brain and Behavior. 20
In a previous genome-wide association study (GWAS) using outbred Carworth Farms White (CFW) mice, we identified a locus that influenced the stimulant response to methamphetamine and colocalized with an eQTL for Azi2. Based on those findings, we hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2ff306ed036a15f65d688c9ee67eb3
https://doi.org/10.1111/gbb.12760
https://doi.org/10.1111/gbb.12760
Autor:
Abraham A. Palmer, Binnaz Yalcin, Oliver Stegle, Jérôme Nicod, Amanda M. Barkley-Levenson, Charlotte Montillot, Francesco Paolo Casale, Amelie Baud, Nilgoun Farhadi
Publikováno v:
Genome Biology
Genome Biology, 2021, 22 (1), pp.216. ⟨10.1186/s13059-021-02415-x⟩
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Genome Biology, 2021, 22 (1), pp.216. ⟨10.1186/s13059-021-02415-x⟩
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Background: The phenotype of an individual can be affected not only by the individual's own genotypes, known as direct genetic effects (DGE), but also by genotypes of interacting partners, indirect genetic effects (IGE). IGE have been detected using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67028a6fa2cbd12f650d837a2b4419b9
http://europepmc.org/articles/PMC8311926
http://europepmc.org/articles/PMC8311926
Autor:
Patricia Montilla-Perez, Francesca Telese, Amanda M. Barkley-Levenson, Abraham A. Palmer, Xinzhu Zhou
Methamphetamine is a widely abused psychostimulant. In a previous genome-wide association study (GWAS), we identified a locus that influenced the stimulant response to methamphetamine. That locus was also an eQTL for the gene Azi2. Based on those fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51edfc47ac96f6011a3c7407504b627a
https://doi.org/10.1101/2020.08.22.262709
https://doi.org/10.1101/2020.08.22.262709
Autor:
Amanda M. Barkley-Levenson, Marcia J. Ramaker, Leggy A. Arnold, Margaret L. Guthrie, Katherine M.J. McMurray, Abraham A. Palmer, M K Reddy, James M. Cook, Viresh H. Rawal, Preetpal S. Sidhu, P K Elkin, Stephanie C. Dulawa
Publikováno v:
Molecular psychiatry
Current pharmacotherapies for depression exhibit slow onset, side effects and limited efficacy. Therefore, identification of novel fast-onset antidepressants is desirable. GLO1 is a ubiquitous cellular enzyme responsible for the detoxification of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890a48e0787e174f34bde6b45fc3faec
https://doi.org/10.1038/mp.2017.14
https://doi.org/10.1038/mp.2017.14
Autor:
Peter F. Glatt, Amanda M. Barkley-Levenson, Benjamin L. Dick, Seth M. Cohen, Jeremiah D. Momper, Christian Perez, Dionicio Siegel, Abraham A. Palmer, Yadira Martinez
Publikováno v:
Journal of medicinal chemistry, vol 62, iss 3
Anxiety and depression are common, highly comorbid psychiatric diseases that account for a large proportion of worldwide medical disability. Glyoxalase 1 (GLO1) has been identified as a possible target for the treatment of anxiety and depression. GLO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a9dca2e41ba69043fadefbd6081808
https://escholarship.org/uc/item/9mk9c3df
https://escholarship.org/uc/item/9mk9c3df