Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M A Labow"'
Publikováno v:
Molecular and Cellular Biology. 10:3343-3356
A novel mammalian regulatory system was created by using the Escherichia coli lac repressor. The lac repressor was converted into a mammalian transcriptional activator by modifying the lac repressor coding region to include a nuclear localization sig
Autor:
E B, Cullinan, L, Kwee, P, Nunes, D J, Shuster, G, Ju, K W, McIntyre, R A, Chizzonite, M A, Labow
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(10)
The recently described IL-1R accessory protein (IL-1R AcP) interacts with IL-1beta and the IL-1 type-IR (IL-1RI), but an essential requirement for IL-1R AcP in IL-1 signaling in vitro has not been established and its role in vivo has not been examine
Publikováno v:
Pharmaceutical research. 14(10)
During long-term treatment of various malignant or viral diseases with IFN-alpha up to 20% of patients develop anti-IFN-alpha antibodies for as yet unknown reasons.To address this issue, a mouse model using Balb/C mice was established and the relevan
Publikováno v:
Transgenic research. 6(5)
A conditional null allele for VCAM-1 was generated in mice through a one step ES cell selection procedure by flanking the proximal promoter and exons 1 and 2 with loxP sites. The ES cells were used to create chimeric mice, which were then used to pro
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(12)
In an effort to isolate novel genes involved in inflammation and/or mast cell activation, we have used a combination of differential screening and subtractive hybridization to isolate genes whose expression are induced upon activation of a transforme
Publikováno v:
Development (Cambridge, England). 121(2)
VCAM-1 is a cytokine-inducible cell surface protein capable of mediating adhesion to leukocytes expressing α4 integrins. Mice deficient in VCAM-1 expression were produced by targeted homologous recombination in ES cells. VCAM-1-deficient embryos wer
Autor:
M A, Labow
Publikováno v:
Methods in enzymology. 254
Publikováno v:
Journal of virology. 65(6)
A feature of the cascade regulation of herpes simplex virus 1 gene expression in productive infection is that the first genes to be expressed, the alpha genes, are transactivated by a structural component of the virion designated as the alpha transin
Autor:
M A Labow, Kenneth I. Berns
Publikováno v:
Journal of General Virology. 68:601-614
Introduction. The parvoviruses are among the smallest of the DNA animal viruses (Siegl et al., 1985). The genome is a linear single-stranded DNA of approximately 5 kb which is encapsidated in a naked icosahedral virion 20 to 26 nm in diameter. There
Publikováno v:
Journal of Virology. 51:329-339
We constructed insertion and deletion mutants with mutations within the adeno-associated virus (AAV) sequences of the infectious recombinant plasmid pSM620. Studies of these mutants revealed at least three AAV phenotypes. Mutants with mutations betwe