Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M A Hassan Talukder"'
Autor:
Jung Il Lee, M A Hassan Talukder, Zara Karuman, Anagha A Gurjar, Prem Kumar Govindappa, Jagadeeshaprasad M Guddadarangaiah, Kristen M Manto, Grant D Wandling, John P Hegarty, David L Waning, John C Elfar
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 2, Pp 439-444 (2023)
We recently demonstrated a repurposing beneficial effect of 4-aminopyridine (4-AP), a potassium channel blocker, on functional recovery and muscle atrophy after sciatic nerve crush injury in rodents. However, this effect of 4-AP is unknown in nerve t
Externí odkaz:
https://doaj.org/article/a1b092dcd6af4682a605ab845e0bdebd
Publikováno v:
Bio-Protocol, Vol 12, Iss 5 (2022)
Peripheral nerve injury (PNI) is common in all walks of life, and the most common PNIs are nerve crush and nerve transection. While optimal functional recovery after crush injury occurs over weeks, functional recovery after nerve transection with mic
Externí odkaz:
https://doaj.org/article/4cd61f47070847ac9ae4ce5e51290c52
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 11, Pp 2098-2107 (2020)
4-Aminopyridine (4-AP), an FDA-approved drug for the symptomatic treatment of multiple sclerosis, is used to improve neuromuscular function in patients with diverse demyelinating disorders. We recently demonstrated that local, transdermal or injectab
Externí odkaz:
https://doaj.org/article/883ff66216f44132a69f7d50200a5235
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 1, Pp 136-144 (2020)
Oral 4-aminopyridine (4-AP) is clinically used for symptomatic relief in multiple sclerosis and we recently demonstrated that systemic 4-AP had previously unknown clinically-relevant effects after traumatic peripheral nerve injury including the promo
Externí odkaz:
https://doaj.org/article/befefddb0b4a46238df64b8bb2e6169a
Autor:
Kristen M. Manto, Prem Kumar Govindappa, Brandon Martinazzi, Aijie Han, John P. Hegarty, Zachary Koroneos, M. A. Hassan Talukder, John C. Elfar
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Traumatic peripheral nerve injury (TPNI) is a major medical problem with no universally accepted pharmacologic treatment. We hypothesized that encapsulation of pro-angiogenic erythropoietin (EPO) in amphiphilic PLGA-PEG block copo
Externí odkaz:
https://doaj.org/article/9c0daaf8950f407c90cd8616025ea410
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Clinical and experimental evidence indicate that increased vascular permeability contributes to many disease-associated vascular complications. Oxidative stress with increased production of reactive oxygen species (ROS) has been implicated in a wide
Externí odkaz:
https://doaj.org/article/68d894f917764a7ba6fbd2c076c39791
Autor:
Brandon Martinazzi, John P. Hegarty, John C. Elfar, Prem Kumar Govindappa, Kristen M. Manto, M A Hassan Talukder, Zara Karuman, Daniele Parisi
Publikováno v:
ACS Appl Bio Mater
Traumatic peripheral nerve injury (TPNI) represents a major medical problem that results in loss of motor and sensory function, and in severe cases, limb paralysis and amputation. To date, there are no effective treatments beyond surgery in selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3526b5c4ffa47f3ea47a2e2c8c9c71
https://doi.org/10.1021/acsabm.0c01566
https://doi.org/10.1021/acsabm.0c01566
Autor:
John C. Elfar, M A Hassan Talukder, Zara Karuman, Jung Il Lee, Kristen M. Manto, Anagha Gurjar, Mary O'Brien, Andrew Rodenhouse, Prem Kumar Govindappa
Publikováno v:
Mil Med
Background Functional recovery following primary nerve repair of a transected nerve is often poor even with advanced microsurgical techniques. Recently, we developed a novel sciatic nerve transection method where end-to-end apposition of the nerve en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea1e0eec1887acd4136de9b462c2ebc
https://doi.org/10.1093/milmed/usaa344
https://doi.org/10.1093/milmed/usaa344
Novel Real-time Digital Pressure Sensor Reveals Wide Variations in Current Nerve Crush Injury Models
Publikováno v:
Mil Med
Introduction: Peripheral nerve crush injury (PNCI) models are commonly used to study nerve damage and the potential beneficial effects of novel therapeutic strategies. Current models of PNCI rely on inter-device and operator precision to limit the va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cdc5ce3394e2a3af174df35e072c48
https://doi.org/10.1093/milmed/usaa346
https://doi.org/10.1093/milmed/usaa346
Autor:
Anagha Gurjar, M A Hassan Talukder, Prem Kumar Govindappa, John C. Elfar, Mary O'Brien, Kristen M. Manto, Andrew Rodenhouse, Jung Il Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Peripheral nerve transection is associated with permanent functional deficit even after advanced microsurgical repair. While it is difficult to investigate the reasons of poor functional outcomes of microsurgical repairs in humans, we developed a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b902aa0b2e8bd5feb49e471b9d93d5ff
https://doaj.org/article/b4bbef15c8ee41bd81c3c82b57a1d8cc
https://doaj.org/article/b4bbef15c8ee41bd81c3c82b57a1d8cc