Are needle-free injections a useful alternative for growth hormone therapy in children? Safety and pharmacokinetics of growth hormone delivered by a new needle-free injection device compared to a fine gauge needle

Autor: A M Wilson, H G Dörr, B K Gillespie, M A van Kuijck, B J Otten, S L Schoenfeld, L Nyman, Eberhard Keller, N R Lester, Cecilia Hyrén, Carl-Joachim Partsch, P Schuld, S Zabransky

Publikováno v: Journal of Pediatric Endocrinology & Metabolism, 16, 3, pp. 383-92
Journal of Pediatric Endocrinology & Metabolism, 16, 383-92

Item does not contain fulltext The clinical safety, use and pharmacokinetics of a new needle-free device for delivery of growth hormone (GH) were compared with those of conventional needle injection devices. In an open-label, randomized, 4-period cro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4242ac4d8b6d02a2cfbd1e4d11e9cd1
https://pubmed.ncbi.nlm.nih.gov/12705363

Adenosine triphosphate-dependent transport of anionic conjugates by the rabbit multidrug resistance-associated protein Mrp2 expressed in insect cells

Autor: R A, van Aubel, M A, van Kuijck, J B, Koenderink, P M, Deen, C H, van Os, F G, Russel

Publikováno v: Molecular pharmacology. 53(6)

The multidrug resistance-associated protein Mrp2 is expressed in liver, kidney, and small intestine and mediates ATP-dependent transport of conjugated organic anions across the apical membrane of epithelial cells. We recently cloned a rabbit cDNA enc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3264fe995de163bf30f61058964342ac
https://pubmed.ncbi.nlm.nih.gov/9614209