Outcomes of First-Line Chemotherapy in Patients with Advanced or Metastatic Leiomyosarcoma of Uterine and Non-Uterine Origin

Autor: A. W. Oosten, C. Seynaeve, P. I. M. Schmitz, M. A. den Bakker, J. Verweij, S. Sleijfer

Publikováno v: Sarcoma, Vol 2009 (2009)

Although leiomyosarcomas (LMSs) form the largest subgroup of soft tissue sarcomas (STSs), the efficacy of chemotherapy in this group is largely unclear, partly because older studies are contaminated with gastrointestinal stromal tumors (GISTs). In th

Externí odkaz: https://doaj.org/article/a5da7d5d0a0f4b1c917eaa6dfc3bb2ea

DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile

Autor: Ronald A M Damhuis, PALGA-group, Ernst-Jan M. Speel, Egbert F. Smit, E C van den Broek, Jules L. Derks, A-M.C. Dingemans, A Ruland, B.C.M. Hermans, Erik Thunnissen, R.J. van Suylen, M A den Bakker, Harry J.M. Groen

Publikováno v: Hermans, B C M, Derks, J L, Thunnissen, E, van Suylen, R J, den Bakker, M A, Groen, H J M, Smit, E F, Damhuis, R A, van den Broek, E C, Ruland, A, Speel, E J M, Dingemans, A M C & PALGA-Group 2019, ' DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile ', Lung Cancer, vol. 138, pp. 102-108 . https://doi.org/10.1016/j.lungcan.2019.10.010
Lung Cancer, 138, 102-108. Elsevier Ireland Ltd
Lung Cancer, 138, 102-108. ELSEVIER IRELAND LTD

Objectives: For stage IV pulmonary large cell neuroendocrine carcinoma (LCNEC), the only therapeutic option is palliative chemotherapy. DLL3 is a new therapeutic target, which seems to be often expressed in SCLC and LCNEC. It has recently been report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545c518fe922e2720372edf6733ec67d
https://research.vumc.nl/en/publications/a86c5ffc-3cd3-48e2-8e9d-e2b7586944c0

[Is histopathology still the gold standard?]

Autor: M A, den Bakker

Publikováno v: Nederlands tijdschrift voor geneeskunde. 160

In the diagnostic process, microscopical analysis is considered to be the gold standard in determining the presence and nature of a disease. In some cases, in particular in rare diseases and in precursor lesions in which pathological changes have not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28892e8b1bcded4465f83c86c939b48b
https://pubmed.ncbi.nlm.nih.gov/28120732

A population based analysis of outcome of chemotherapy for metastatic pulmonary large cell neuroendocrine carcinomas:does the regimen matter?

Autor: Erik Thunnissen, Jules L. Derks, E. J. Speel, Hendricus Groen, M A den Bakker, Anne-Marie C. Dingemans, R.J. van Suylen, E.F. Smit, Ronald A M Damhuis

Publikováno v: Derks, J L, van Suylen, R J, Thunnissen, E, Den Bakker, M A, Groen, H, Smit, E F, Damhuis, R A, Speel, E J & Dingemans, A M C 2016, ' A population based analysis of outcome of chemotherapy for metastatic pulmonary large cell neuroendocrine carcinomas : does the regimen matter? ', Annals of Oncology, vol. 27, pp. vi139 . https://doi.org/10.1093/annonc/mdw369.11, https://doi.org/10.1093/annonc/mdw369.11
Annals of Oncology, 27. Oxford University Press

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2a8f2fccf835543f11561c3f65ca12
https://research.vumc.nl/en/publications/240f3037-ebb5-40b1-a81c-0f4c69b204b5

Circulating endothelial cells in oncology: pitfalls and promises

Autor: Stefan Sleijfer, Jaco Kraan, Cor H. J. Lamers, M. A. den Bakker, Michiel Strijbos, Jan-Willem Gratama

Publikováno v: British Journal of Cancer
British Journal of Cancer, 98(11), 1731-1735. Nature Publishing Group

Adequate blood supply is a prerequisite in the pathogenesis of solid malignancies. As a result, depriving a tumour from its oxygen and nutrients, either by preventing the formation of new vessels, or by disrupting vessels already present in the tumou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81cf465c98c6368753404a5504496f4
https://hdl.handle.net/1765/29159