Zobrazeno 1 - 2
of 2
pro vyhledávání: '"M A, Shudrov"'
Autor:
E V, Dolgova, V A, Rogachev, V P, Nikolin, N A, Popova, A S, Likhacheva, E A, Aliamkina, T E, Sebeleva, E R, Chernykh, E L, Gel'fgat, S S, Bogachev, M A, Shudrov
Publikováno v:
Voprosy onkologii. 55(6)
Our study showed that protamine (80% w/w to DNA) effectively protected its molecules from degradation by native nucleases of the mammalian blood serum. Exogenous DNA bound to protamine effectively stimulated restoration of cyclophosphamide-induced le
Autor:
E A, Aliamkina, A S, Likhacheva, V P, Nikolin, N A, Popova, E V, Dolgova, V A, Rogachev, T E, Sebeleva, D N, Strunkin, S S, Bogachev, M A, Shudrov
Publikováno v:
Voprosy onkologii. 55(6)
DNA unprotected by protamine immediately degraded to fragments of a 200 bp size in the blood flow of experimental animals to be delivered to the innermost compartments of tumor cells. Once absorbed by protamine, DNA fragment remained unchanged in siz