Zobrazeno 1 - 10
of 22
pro vyhledávání: '"M A, Karsdal"'
Autor:
H. Jessen, N. Hoyer, T. S. Prior, P. Frederiksen, M. A. Karsdal, D. J. Leeming, E. Bendstrup, J. M. B. Sand, S. B. Shaker
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-8 (2021)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of fibrillar collagens in the alveolar space resulting in reduced pulmonary function and a high mortality rate. Biomarkers measuring the turnover of type I a
Externí odkaz:
https://doaj.org/article/583b6aa04c744880a295534dba10812f
Autor:
L. B. Steffensen, J. Stubbe, J. S. Lindholt, H. C. Beck, M. Overgaard, M. Bloksgaard, F. Genovese, S. Holm Nielsen, M. L. T. Tha, S. K. Bang-Moeller, M. K. T. Hong Lin, J. H. Larsen, D. R. Hansen, G. T. Jones, M. J. Bown, M. A. Karsdal, L. M. Rasmussen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Abdominal aortic aneurysm (AAA) is a complex disease which is incompletely accounted for. Basement membrane (BM) Collagen IV (COL4A1/A2) is abundant in the artery wall, and several lines of evidence indicate a protective role of baseline COL
Externí odkaz:
https://doaj.org/article/3d1b5c247947475dacbe108ba6ec5da2
Autor:
D. J. Leeming, F. Genovese, J. M. B. Sand, D. G. K. Rasmussen, C. Christiansen, G. Jenkins, T. M. Maher, J. Vestbo, M. A. Karsdal
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-7 (2021)
Abstract Pulmonary fibrosis has been identified as a main factor leading to pulmonary dysfunction and poor quality of life in post-recovery Severe Acute Respiratory Syndrome (SARS) survivor’s consequent to SARS-Cov-2 infection. Thus there is an urg
Externí odkaz:
https://doaj.org/article/b2bcb051f0eb42c39bfcd4b1227ec0bd
Autor:
M Sorokina Alexdóttir, M Pehrsson, M A Karsdal, L E Godskesen, A Krag, J Kjeldsen, J H Mortensen
Publikováno v:
Journal of Crohn's and Colitis. 17:i349-i351
Background Inflammatory bowel disease (IBD) is characterized by chronic inflammation due to an uncontrolled immune response orchestrated through, i.e. neutrophils. The basement membrane acts as a front-line defense promoting tissue integrity, where t
Autor:
S.N. Kehlet, C.L. Bager, N. Willumsen, B. Dasgupta, C. Brodmerkel, M. Curran, S. Brix, D.J. Leeming, M. A. Karsdal
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Decorin is one of the most abundant proteoglycans of the extracellular matrix and is mainly secreted and deposited in the interstitial matrix by fibroblasts where it plays an important role in collagen turnover and tissue homeosta
Externí odkaz:
https://doaj.org/article/c910558183aa4d0a907f0182bf0a725f
Autor:
J M B Sand, A Hummersgaard Hansen, E A Madsen, J Thorlacius-Ussing, T S Prior, M A Karsdal, D J Leeming, E Bendstrup
Publikováno v:
12.01 - Idiopathic interstitial pneumonias.
Publikováno v:
03.03 - Mechanisms of lung injury and repair.
Autor:
J Mortensen, G Focht, M Pehrsson, A M Griffiths, M S Alexdóttir, A Quteineh, P C Church, R N Baldassano, J Silverstein, M A Karsdal, D Turner
Publikováno v:
Journal of Crohn's and Colitis. 17:i458-i459
Background Mucosal healing (MH) has become a treatment goal for inflammatory bowel disease (IBD), especially for ulcerative colitis. However, MH is less feasible to assess frequently in patients with Crohn’s disease (CD). In this study, we investig
Autor:
M Sorokina Alexdóttir, A R Bourgonje, M A Karsdal, A C Bay-Jensen, M Pehrsson, R Loveikyte, H M van Dullemen, M C Visschedijk, E A M Festen, R K Weersma, K N Faber, G Dijkstra, M Joachim H
Publikováno v:
Journal of Crohn's and Colitis. 16:i468-i469
Background Crohn‘s disease (CD) is a form of inflammatory bowel disease characterized by high infiltration of immune cells into the intestinal tissue, resulting in increased proteolytic mediated extracellular matrix (ECM) remodeling. Disease manage
Autor:
J Mortensen, G Focht, M Pehrsson, A M Griffiths, M S Alexdóttir, P C Church, R N Baldassano, A C Bay-Jensen, J Silverstein, M A Karsdal, D Turner
Publikováno v:
Journal of Crohn's and Colitis. 16:i264-i265
Background Most patients with inflammatory bowel disease (IBD) eventually develop intestinal fibrosis due to increased extracellular matrix (ECM) remodelling. There is a huge medical need for non-invasive serological biomarkers for intestinal fibrosi