Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M A, Eldon"'
Publikováno v:
Therapeutic drug monitoring. 20(1)
Procainamide hydrochloride is a Class 1A antiarrhythmic agent administered intravenously or orally for treatment of symptomatic ventricular premature depolarizations (VPD), nonsustained ventricular tachycardia, and life-threatening ventricular arrhyt
Publikováno v:
Biopharmaceuticsdrug disposition. 17(6)
To assess the delivery characteristics of a new 7 day 17 beta-estradiol transdermal delivery system (TDS), estradiol and estrone pharmacokinetics were evaluated following a single 7 d application of one TDS or two TDSs in 24 healthy, postmenopausal w
Autor:
M. A. Eldon, U. Hoch
Publikováno v:
Journal of Clinical Oncology. 29:2598-2598
2598 Background: NKTR-102 demonstrates significant anti-tumor activity with a tolerable toxicity profile in pts with platinum-resistant/refractory ovarian or metastatic breast cancers. NKTR-102 is ...
Publikováno v:
Pharmaceutical research. 10(4)
The pharmacokinetics and relative oral bioavailability of procaterol, an orally active beta 2-adrenergic agonist bronchodilator were evaluated in healthy volunteers. Procaterol was rapidly absorbed after oral administration. Mean plasma procaterol co
Autor:
C L, Webb, M A, Eldon
Publikováno v:
Pharmaceutical research. 8(11)
Autor:
M A, Eldon, W A, Colburn
Publikováno v:
Pharmaceutical research. 7(6)
Publikováno v:
The Journal of Clinical Pharmacology. 27:226-232
The effects of acute withdrawal from cigarette smoking on indocyanine green (ICG) clearance and antipyrine pharmacokinetics were studied in healthy young male volunteers. Two separate crossover clinical trials, each using 12 subjects, were used to co
Publikováno v:
Journal of clinical pharmacology. 27(3)
The intravenous disposition of theophylline was determined in 12 healthy young male smokers during periods of smoking and short-term withdrawal (24 to 36 hours), using a crossover design. Median half-life, clearance, volume of distribution, hepatic e
Autor:
H R, Maxon, W A, Ritschel, C P, Volle, M A, Eldon, I W, Chen, M F, Fernandez, J, Cline, G, Mayfield
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 21(8)
The absolute and relative bioavailability of levothyroxine was determined in young, healthy male subjects after administration of i.v. solution, p.o. solution, or one of two brand-name, commercially available tablets. The mean dose size was about 0.1
Autor:
W A, Ritschel, M A, Eldon
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 7(7)
A programmable calculator procedure for the determination of dosage regimens to achieve desired steady state concentrations is described. The dosage regimen prediction is based on data from the literature on pharmacokinetic parameters of drugs and co