Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M A, Eakin"'
Autor:
Keith Blakeney Mallion, M. C. Johnson, Brown George Robert, Alan J. Foubister, D. Griffiths, Susan Freeman, S. Chapman, M. A. Eakin, Harrison Peter John, R. J. Butlin
Publikováno v:
Journal of Medicinal Chemistry. 38:4157-4160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adaa96fbc17e951473ddcb37976b66b
https://doi.org/10.1021/jm00021a003
https://doi.org/10.1021/jm00021a003
Autor:
M C, Eakin
Publikováno v:
Latin American research review. 34(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0ff46ffec19bd2247a10b4c820cf12a
https://pubmed.ncbi.nlm.nih.gov/22003565
https://pubmed.ncbi.nlm.nih.gov/22003565
Autor:
R. P. Walker, Alan J. Foubister, Brown George Robert, Graham J. Smith, Susan Freeman, M. A. Eakin, Harrison Peter John, D. Griffiths, M. J. Taylor, P. R. O. Whittamore, Fergus McTaggart, A. C. Reid, Keith Blakeney Mallion, M. C. Johnson, R. J. Butlin, S. Chapman
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f40453be6fac695470074a52d5577099
https://doi.org/10.1002/chin.199607114
https://doi.org/10.1002/chin.199607114
Autor:
Donald J. Mirrlees, Alan J. Foubister, David S. Clarke, Fergus McTaggart, Robin Wood, M. A. Eakin, M. C. Johnson, Brown George Robert, D. Griffiths, Graham J. Smith, Steven C. Glossop, Stokes Elaine Sophie Elizabeth, David M. Hollinshead
Publikováno v:
Journal of medicinal chemistry. 42(7)
Novel 3-substituted quinuclidine inhibitors of cholesterol biosynthesis are reported. Compounds were optimized against oxidosqualene cyclase-lanosterol synthase (OSC) inhibition in vivo, rather than by the conventional optimization of structure-activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b521dff6bea4b5800ec381b0617296
https://pubmed.ncbi.nlm.nih.gov/10197973
https://pubmed.ncbi.nlm.nih.gov/10197973
Autor:
Dyral C. Fessler, Ira S. Krull, S. M. Thomas, S. Morris Kupchan, Thomas J. Giacobbe, M. Allan. Eakin
Publikováno v:
The Journal of Organic Chemistry. 35:3539-3543
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02f65c75d8546c12e29fd5eb76d55dcf
https://doi.org/10.1021/jo00835a078
https://doi.org/10.1021/jo00835a078
Autor:
S. J. Harland, Kenneth R. Harrap, R. F. Betteridge, M. A. Eakin, A. J. Hayter, A. H. Calvert, A. Stocker, David R. Newell, M. L. Smithers, Jones Terence R, Ann L. Jackman, L. C. Davies
Publikováno v:
Chemischer Informationsdienst. 17
Synthetisiert werden die N10-Analoga (IIIa), die aber nicht die Wirkung (TS-Inhibierung, Cytotoxizitat) von (IIIb) erreichen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6816aef975d054daf6eeb93bf704ca02
https://doi.org/10.1002/chin.198606194
https://doi.org/10.1002/chin.198606194
Autor:
Ann L. Jackman, M. A. Eakin, A. Stocker, Alan Hilary Calvert, Smithers Mj, S. J. Harland, A. J. Hayter, David R. Newell, Jones Terence R, R. F. Betteridge
Publikováno v:
Journal of medicinal chemistry. 28(10)
The synthesis of 12 new 5,8-dideazafolates with isopropyl, cyclopropylmethyl, 2-fluoroethyl, carbamoylmethyl, phenacyl, 3-fluorobenzyl, 5-uracilylmethyl, carboxymethyl, 2-carboxyethyl, 3-cyanopropyl, 3-hydroxypropyl, and cyanomethyl substituents at N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ba4e9fe38c525cb52eaa2f068453da
https://pubmed.ncbi.nlm.nih.gov/4045922
https://pubmed.ncbi.nlm.nih.gov/4045922
Publikováno v:
Research in veterinary science. 28(2)
In sheep, 3-tert butyl 4'5 dicyano 6 methyl 2' bromo salicylanilide was found to be active against mature Fasciola hepatica down to 0.2 mg/kg but was toxic at 1.5 mg/kg.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9871ac739b18cc4174f190384318ee3d
https://pubmed.ncbi.nlm.nih.gov/7414076
https://pubmed.ncbi.nlm.nih.gov/7414076
Publikováno v:
Journal of medicinal chemistry. 14(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a60f11b96fb635defda0d5ae231e484
https://pubmed.ncbi.nlm.nih.gov/5116225
https://pubmed.ncbi.nlm.nih.gov/5116225
Publikováno v:
Chemischer Informationsdienst. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34049007f017773fdf179a91287823d1
https://doi.org/10.1002/chin.197218267
https://doi.org/10.1002/chin.197218267