Zobrazeno 1 - 10
of 110
pro vyhledávání: '"M A, Dumpis"'
Autor:
Elena V. Litasova, Dmitrii N. Nikolayev, Levon B. Piotrovskiy, Viktor V. Iljin, M. A. Dumpis, Marija A. Brusina
Publikováno v:
Reviews on Clinical Pharmacology and Drug Therapy. 18:313-326
The review discusses in detail the causes of side effects of drugs, caused, inter alia, by the high complexity of the organism. The different ways are represented to overcome this problem by creating, in particular, targeted delivery systems. But nev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83739e7891aeec53d1a241fea0b25e08
https://doi.org/10.17816/rcf184313-326
https://doi.org/10.17816/rcf184313-326
Autor:
Dmitrii N. Nikolayev, M. A. Dumpis, Mariya A. Brusina, Levon B. Piotrovsky, Elena V. Litasova, Viktor V. Iljin
Publikováno v:
Reviews on Clinical Pharmacology and Drug Therapy. 16:4-20
The review deals with the properties of fullerenes and their derivatives and the possibility of their use in biology and medicine. Fullerenes can exert an antioxidant effect in biological systems, catching active forms of oxygen, and oxidative, givin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b9a64c7c109d3c61dc71a246c967f87
https://doi.org/10.17816/rcf1614-20
https://doi.org/10.17816/rcf1614-20
Publikováno v:
Pharmaceutical Chemistry Journal. 51:881-883
A complex of fullerene C60 and dihydroquercetin (DHQC) was synthesized. Its biological activity in a model system was studied using chemiluminometry. It was established that the C60/DHQC complex possessed antioxidant activity, which prompted further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74ecedff10ea49ea9426a9a6b86db8a5
https://doi.org/10.1007/s11094-018-1709-5
https://doi.org/10.1007/s11094-018-1709-5
Autor:
M. A. Dumpis, V. V. Iljin, L. B. Piotrovskiy, E. V. Litasova, Alexey V. Sokolov, V. B. Vasilyev
Publikováno v:
Doklady Biochemistry and Biophysics. 471:417-420
It is shown for the first time that the mammalian enzymes can cause the degradation of the C60 fullerene molecules. This biodegradation is caused by the action of а hypochlorite generated neutrophil enzyme myeloperoxidase of fullerene molecule and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287615cf1af47e842436867569a786a4
https://doi.org/10.1134/s1607672916060119
https://doi.org/10.1134/s1607672916060119
Autor:
Valentina V. Bulion, M. A. Dumpis, Irina V. Okunevich, Albina F. Safonova, Dmitry N. Nikolaev, Elena N. Selina, Viktor V. Iljin, Olga M. Rodionova, I. B. Krylova, Elena V. Litasova, Levon B. Piotrovsky
Publikováno v:
Advances in nano research. 4:167-179
The detailed study of acute and sub-acute toxicity of the complex polyvinylpyrrolidon (PVP 20 kDa)-wrapped fullerene after intraperitoneal (ip) administration was carried out on adult male Wistar rats. The value of complex was found to be 7, 8 g/kg.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::210c8924c783da15f935b814fdcf928e
https://doi.org/10.12989/anr.2016.4.3.167
https://doi.org/10.12989/anr.2016.4.3.167
Publikováno v:
Doklady. Biochemistry and biophysics. 471(1)
It is shown for the first time that the mammalian enzymes can cause the degradation of the C60 fullerene molecules. This biodegradation is caused by the action of а hypochlorite generated neutrophil enzyme myeloperoxidase of fullerene molecule and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1fadc213a24d29c801daa5af74f5fb6
https://pubmed.ncbi.nlm.nih.gov/28058679
https://pubmed.ncbi.nlm.nih.gov/28058679
Autor:
E. M. Eropkina, M. Yu. Eropkin, Levon B. Piotrovsky, Elena V. Litasova, Oleg I. Kiselev, M. A. Dumpis, E. V. Ilyinskaya
Publikováno v:
Biophysics. 57:343-349
In view of contradictory data on the toxicity of fullerenes for living organisms we studied the effect of water-soluble complexes of C60 with N-polyvinylpyrrolidone (C60/PVP) and γ-cyclodextrin (C60/γ-CD) on MA-104 cells in culture. Both complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b87defa3f9e93707ffb481483ac5b79f
https://doi.org/10.1134/s0006350912030074
https://doi.org/10.1134/s0006350912030074
Autor:
E. M. Eropkina, Elena V. Litasova, Levon B. Piotrovsky, M. A. Dumpis, M. Yu. Eropkin, Oleg I. Kiselev
Publikováno v:
Fullerenes, Nanotubes and Carbon Nanostructures. 19:147-153
The biological effects in vitro of two water soluble inclusions complexes of C60/ polyvinylpyrrolidone (C60/PVP) and C60/γ-cyclodextrin (C60/γ-CD), and also the crystalline C60 (as fullerene-covered surface) were studied. It was found that both the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b379138dd141f5310000e36193aca5e2
https://doi.org/10.1080/1536383x.2010.490141
https://doi.org/10.1080/1536383x.2010.490141
Autor:
L. B. Piotrovsky, V. A. Popov, R. H. Karaev, O. B. Zaitseva, M. A. Dumpis, N. V. Sirotinkin, M. A. Tyunin
Publikováno v:
Fullerenes, Nanotubes and Carbon Nanostructures. 16:693-697
The absence of acute toxicity of pristine fullerene C60 (3.5–8.9 mg/kg) after intraperitoneal injection of water soluble C60/PVP complex to rats was shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a50ba991f58501370cb01c7cf80b9d
https://doi.org/10.1080/15363830802317130
https://doi.org/10.1080/15363830802317130
Autor:
A. Yu. Bespalov, D. N. Nikolaev, E. E. Yakovleva, L. B. Piotrovskiy, E. V. Litasova, Olga A. Dravolina, M. A. Dumpis
Publikováno v:
Doklady. Biochemistry and biophysics. 468(1)
The present report describes development of hexamethonium complexes based on fullerene C60. Hexamethonium has a limited penetration into CNS and therefore can antagonize central effects of nicotine only when given at high doses. In the present studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e7daedc29f2bb490190f3b17b17bc4
https://pubmed.ncbi.nlm.nih.gov/27417712
https://pubmed.ncbi.nlm.nih.gov/27417712