Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M A, De Bastiani"'
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Alzheimer’s disease (AD) is a multifactorial and complex neuropathology that involves impairment of many intricate molecular mechanisms. Despite recent advances, AD pathophysiological characterization remains incomplete, which h
Externí odkaz:
https://doaj.org/article/419554cd9ab54289af253afcb0a13a26
Autor:
N. R. Strogulski, A. Kopczynski, V. G. de Oliveira, R. B. Carteri, G. Hansel, G. T. Venturin, S. Greggio, J. C. DaCosta, M. A. De Bastiani, M. S. Rodolphi, L. V. Portela
Publikováno v:
Neurochemical Research. 47:2032-2042
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::143c0fb103df36535764af4f77ac76a5
https://doi.org/10.1007/s11064-022-03592-2
https://doi.org/10.1007/s11064-022-03592-2
Publikováno v:
Molecular Neurobiology. 58:1517-1534
Parkinson's disease (PD) is among the most prevalent neurodegenerative diseases. Available evidences support the view of PD as a complex disease, being the outcome of interactions between genetic and environmental factors. In face of diagnosis and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f6601c4ce6b4b29976d867c22451b2c
https://doi.org/10.1007/s12035-020-02203-x
https://doi.org/10.1007/s12035-020-02203-x
Autor:
N R, Strogulski, A, Kopczynski, V G, de Oliveira, R B, Carteri, G, Hansel, G T, Venturin, S, Greggio, J C, DaCosta, M A, De Bastiani, M S, Rodolphi, L V, Portela
Publikováno v:
Neurochemical research. 47(7)
Decreased anabolic androgen levels are followed by impaired brain energy support and sensing with loss of neural connectivity during physiological aging, providing a neurobiological basis for hormone supplementation. Here, we investigated whether nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40d868b07fa5a4d75c0bf1a07e20ba06
https://pubmed.ncbi.nlm.nih.gov/35415802
https://pubmed.ncbi.nlm.nih.gov/35415802
Publikováno v:
Molecular neurobiology. 58(4)
Parkinson's disease (PD) is among the most prevalent neurodegenerative diseases. Available evidences support the view of PD as a complex disease, being the outcome of interactions between genetic and environmental factors. In face of diagnosis and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::460c8c5fb6fd2c758247415a0061472a
https://pubmed.ncbi.nlm.nih.gov/33211252
https://pubmed.ncbi.nlm.nih.gov/33211252
PO-276 Histone acetylation readers BET in hypoxia adaptation in triple negative breast cancer (TNBC)
Autor:
Alan McIntyre, Dilair Baban, M A De Bastiani, I. Ledaki, D. Heery, K. Stefan, Leonardo Lisbôa da Motta, Shozeb Haider, Fábio Klamt, A L Harris
Publikováno v:
ESMO Open. 3:A335
Introduction Hypoxia (low oxygen) is associated with worst prognosis and therapy resistance in most solid tumours. Hypoxia occurs in ~50% of breast cancer, most frequently in triple negative breast cancer (TNBC), the most aggressive subtype. Hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29208b0844507b795b49b00c0f2edb54
https://doi.org/10.1136/esmoopen-2018-eacr25.790
https://doi.org/10.1136/esmoopen-2018-eacr25.790
Autor:
L L, da Motta, I, Ledaki, K, Purshouse, S, Haider, M A, De Bastiani, D, Baban, M, Morotti, G, Steers, S, Wigfield, E, Bridges, J-L, Li, S, Knapp, D, Ebner, F, Klamt, A L, Harris, A, McIntyre
Publikováno v:
Oncogene
The availability of bromodomain and extra-terminal inhibitors (BETi) has enabled translational epigenetic studies in cancer. BET proteins regulate transcription by selectively recognizing acetylated lysine residues on chromatin. BETi compete with thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe67286cb32fb76e93bdde05bbe469f0
https://pubmed.ncbi.nlm.nih.gov/27292261
https://pubmed.ncbi.nlm.nih.gov/27292261
Autor:
Amelia L. Gallitano, Mauro A. A. Castro, Fábio Klamt, Bianca Pfaffenseller, P. V. Da Silva Magalhães, Flávio Kapczinski, M A De Bastiani
Publikováno v:
Translational Psychiatry
Bipolar disorder (BD) is a severe mental illness with a strong genetic component. Despite its high degree of heritability, current genetic studies have failed to reveal individual loci of large effect size. In lieu of focusing on individual genes, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d1ecd30d0c3bb91216de9a9f994dc2
https://doi.org/10.1038/tp.2016.78
https://doi.org/10.1038/tp.2016.78