Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M A, Cukierski"'
Autor:
K. I. Mackenzie, L. F. Kruk, M. A. Cukierski, Alice F. Tarantal, G. L. Skiles, A. P. Clarke, G. S. Harris, K. P. Ellsworth, C. P. Peter, Andrew G Hendrickx, D. S. Ablin, M. J. Vanzwieten, S. Prahalada
Publikováno v:
Teratology. 55:119-131
In genetic male fetuses, dihydrotestosterone (DHT) plays an important role in normal prostatic and external genital differentiation. The enzyme steroid 5-alpha reductase (5 alpha R) catalyzes the conversion of testosterone (T) to DHT. The importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4c7dd1bcfa0608f8095d287ec09ea2f
https://doi.org/10.1002/(sici)1096-9926(199702)55:2<119::aid-tera1>3.0.co
https://doi.org/10.1002/(sici)1096-9926(199702)55:2<119::aid-tera1>3.0.co
Publikováno v:
Primates. 37:351-361
The external characteristics and successive morphological changes of the brain and its derivatives were studied in 69 long-tailed monkey embryos representing developmental stages 8 through 16. This morphogenesis follows a similar pattern to those of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3d79aae0a0c5a7ccc83e54ce02e361
https://doi.org/10.1007/bf02381372
https://doi.org/10.1007/bf02381372
Publikováno v:
Journal of Medical Primatology. 25:122-132
Formation of the definitive kidney in Macaca fascicularis embryos was investigated using light and electron microscopy. Appearance of the definitive kidney at stage 14 was indicated by the ureteric bud invading the metanephrogenic blastema. Glomerula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d375e8a8e21a1260c7bf20617903067
https://doi.org/10.1111/j.1600-0684.1996.tb00203.x
https://doi.org/10.1111/j.1600-0684.1996.tb00203.x
Publikováno v:
Teratology. 51:383-397
Losartan, an AT1-selective angiotensin II receptor antagonist, was evaluated in female rats for effects on fertility, reproduction, and perinatal and postnatal development. In a range-finding study, pregnant rats were treated orally from gestation da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0b6ff6fb3e1acbe5b86af3a3316f6b
https://doi.org/10.1002/tera.1420510604
https://doi.org/10.1002/tera.1420510604
Autor:
R. S. Eydelloth, Jeanne M. Manson, Richard T. Robertson, Henry L. Allen, Stan Spence, M. A. Cukierski
Publikováno v:
Teratology. 51:367-382
Previous developmental and reproductive toxicity studies conducted in rats with Losartan, a potent AT1 subtype selective angiotensin II receptor antagonist, noted treatment-related effects on the pups of dams treated beyond the second trimester throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465207938f069e93b393d1a127efeeac
https://doi.org/10.1002/tera.1420510603
https://doi.org/10.1002/tera.1420510603
Publikováno v:
Neonatology. 68:62-74
Porcine growth hormone was given subcutaneously twice daily to two groups of 20 females at dose levels of 0.5 and 2.5 IU/kg (1 and 5 IU/kg/day). A control group of 20 females was similarly treated with vehicle. The females were given either vehicle o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca781b4d0647352445e55f2f723f9d2
https://doi.org/10.1159/000244219
https://doi.org/10.1159/000244219
Autor:
C. J. Woyden, M. J. Novy, Mark G. Bock, Bradley V. Clineschmidt, B. E. Evans, E V Lis, Terry W. Schorn, K. L. Thompson, Peter K. S. Siegl, Douglas J. Pettibone, Duane R. Reiss, Peter D. Williams, Doug W. Hobbs, M. A. Cukierski, Maribeth T. Guidotti, Roger M. Freidinger, D. F. Veber, G. J. Haluska, M. J. Cook, M. J. Kaufman, S.-H. L. Chiu
Publikováno v:
Drug Development Research. 30:129-142
L-368,899 [1S-(-7,7-dimethyl-2-endo-(2S-amino-4-(methylsulfonyl)butyramido)-bicyclo(2.2.1)-heptan-1-yl)methanesulfonyl)-4-(2-methylphenyl)piperazine] was characterized in vitro and in vivo as a potent and selective, orally bioavailable oxytocin (OT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d543025961ee32823042a54971256b
https://doi.org/10.1002/ddr.430300305
https://doi.org/10.1002/ddr.430300305
Autor:
S, Prahalada, L, Rhodes, S J, Grossman, D, Heggan, K P, Keenan, M A, Cukierski, C M, Hoe, C, Berman, M J, van Zwieten
Publikováno v:
The Prostate. 35(3)
In rats, the prostate is divided into three distinct lobes, and the lobes are dependent on androgens [testosterone (T) and dihydrotestosterone (DHT)] as trophic hormones. However, the reasons for the difference in the incidence of proliferative chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2784f8d1c4843a89100b941e3936bad
https://pubmed.ncbi.nlm.nih.gov/9582084
https://pubmed.ncbi.nlm.nih.gov/9582084
Autor:
S, Prahalada, A F, Tarantal, G S, Harris, K P, Ellsworth, A P, Clarke, G L, Skiles, K I, MacKenzie, L F, Kruk, D S, Ablin, M A, Cukierski, C P, Peter, M J, vanZwieten, A G, Hendrickx
Publikováno v:
Teratology. 55(2)
In genetic male fetuses, dihydrotestosterone (DHT) plays an important role in normal prostatic and external genital differentiation. The enzyme steroid 5-alpha reductase (5 alpha R) catalyzes the conversion of testosterone (T) to DHT. The importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8865224911d250d7c056dc462dd8a918
https://pubmed.ncbi.nlm.nih.gov/9143092
https://pubmed.ncbi.nlm.nih.gov/9143092
Autor:
B V, Clineschmidt, D J, Pettibone, D R, Reiss, E V, Lis, G J, Haluska, M J, Novy, M J, Cook, M A, Cukierski, M J, Kaufman, M G, Bock
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(3)
Two cyclic hexapeptides unrelated in chemical structure to oxytocin (OT) were shown in vivo to be antagonists of the contractile action of OT on the uterus. In anesthetized rats challenged with OT (1 micrograms/kg) administered as an i.v. bolus, L-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bc80ee4c24aa903d6788c559ded54ee
https://pubmed.ncbi.nlm.nih.gov/2005582
https://pubmed.ncbi.nlm.nih.gov/2005582