Efficacy and safety of pharmacotherapy for Alzheimer’s disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials

Autor: Seibert, M., M��hlbauer, V., Holbrook, J., Voigt-Radloff, S., Brefka, S., Dallmeier, D., Denkinger, M., Sch��nfeldt-Lecuona, C., Kl��ppel, S., von Arnim, C. A. F.

Publikováno v: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2021)
Seibert, M.; Mühlbauer, V.; Holbrook, J.; Voigt-Radloff, S.; Brefka, S.; Dallmeier, D.; Denkinger, M.; Schönfeldt-Lecuona, C.; Klöppel, S.; von Arnim, C. A. F. (2021). Efficacy and safety of pharmacotherapy for Alzheimer’s disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials. Alzheimer's research & therapy, 13(1), p. 131. BioMed Central 10.1186/s13195-021-00867-8

Background: Many patients with Alzheimer's disease (AD) are physically frail or have substantial functional impairments. There is growing evidence that such patients are at higher risk for medication-induced adverse events. Furthermore, frailty seems

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https://doaj.org/article/90ca04f66fb846b8b4eb079c408cd3ee