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Autor:
Shahpasand-Kroner, Hedieh, Siddique, Ibrar, Malik, Ravinder, Linares, Gabriel R., Ivanova, Magdalena I., Ichida, Justin, Weil, Tatjana, Müunch, Jan, Sanchez-Garcia, Elsa, Klärner, Frank-Gerrit, Schrader, Thomas, Bitan, Gal, Münch, Jan
Publikováno v:
Pharmacological Reviews. 75:263-308
Lysine-selective molecular tweezers (MTs) are supramolecular host molecules displaying a remarkably broad spectrum of biological activities. MTs act as inhibitors of the self-assembly and toxicity of amyloidogenic proteins using a unique mechanism. T