Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mónika Gallai"'
Publikováno v:
Magyar Onkológia. 54:169-178
Absztrakt A microsatellita-instabilitas (MSI) hozzajarul a vastagbelrak kialakulasahoz, befolyasolja annak varhato korlefolyasat es a szemelyre szabott daganatellenes kezeles korulmenyeit. Az MSI a daganat morfologiai megjelenesenek megvaltozasaval i
Autor:
Szilvia Ecsedi, Margit Balázs, Zoltán Szentirmay, Márk Barok, Ágnes Bégány, Laura Vízkeleti, Zsuzsa Rákosy, Zsuzsa Krekk, Zoltán Vokó, Mónika Gallai, Róza Ádány
Publikováno v:
International Journal of Cancer. 121:1729-1737
Copy number alterations of the epidermal growth factor receptor (EGFR) gene have been extensively analyzed in different cancers, but no data are available for primary malignant melanoma. The aim of the present study was to simultaneously investigate
Autor:
János Lonovics, Katalin Jármay, Ilona Kovalszky, G. Karácsony, Zsófia Ozsvár, Zsuzsa Schaff, Mónika Gallai
Publikováno v:
Journal of Hepatology. 32:993-1002
Background/Aims: Chronic hepatitis C can lead to cirrhosis and hepatocellular carcinoma. Interferon-alfa therapy may prevent the progression of the disease. The expressions of decorin and alfa-smooth muscle cell actin of the extracellular matrix play
Autor:
Renato V. Iozzo, Mónika Gallai, András Jeney, Ilona Kovalszky, Sándor Paku, Julia O. Nagy, Zsuzsa Schafe, Anna Sebestyén
Publikováno v:
Pathology & Oncology Research. 3:51-58
Proteoglycans play key roles in the physiological assembly of extracellular matrices and in the modulation of growth factor activities. During liver regeneration there is a profound remodelling of the connective tissue network with a concurrent alter
Publikováno v:
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. 52(3)
Colorectal carcinomas (CRCs) evolve through multiple pathways. These pathways may be defined based on two molecular features: (1) chromosomal instability and (2) chromosomal stability. Tumors showing chromosomal stability evolve through the so-called
Autor:
Orsolya Szakács, Orsolya Serester, Mónika Gallai, Zoltán Szentirmay, Ildikó Vereczkey, Erika Tóth, Judit Dobos
Publikováno v:
Pathology oncology research : POR. 17(3)
The pathogenesis of ovarian carcinomas is heterogeneous, with even the same entities showing great variance. In our study we investigated the mutations of the BRAF, KRAS, and p53 genes in serous and mucinous borderline tumors and in low grade and hig
Autor:
Ilona, Kovalszky, József, Dudás, Mónika, Gallai, Péter, Hollósi, Péter, Tátrai, Enikô, Tátrai, Zsuzsa, Schaff
Publikováno v:
Magyar onkologia. 48(3)
Proteoglycans are macromolecules formed by a protein core to which sugar chains are covalently attached. They are present on the cell surface and in the ECM of living things. In normal liver syndecan-1 is the dominant transmembrane proteoglycan, trac
Autor:
Jozsef Dudas, Sándor Paku, Mónika Gallai, József Tímár, Ilona Kovalszky, Julianna O. Nagy, Andrea Ladányi
Publikováno v:
Pathology oncology research : POR. 7(4)
Decorin, a member of the family of small leucin-rich proteoglycans, has originally been described as a secreted proteoglycan component of the connective tissues, and has been implicated in the negative regulation of cell proliferation directly or via
Autor:
Zsuzsa Schaff, Mirko Mehde, Thomas Knittel, Katrin Neubauer, Ilona Kovalszky, Giuliano Ramadori, Jozsef Dudas, Mónika Gallai, Julia O. Nagy, Ferenc Szalay
Publikováno v:
American journal of clinical pathology. 115(5)
Decorin is a small extracellular matrix proteoglycan. It binds and modulates transforming growth factor (TGF)-beta 1 action, the major stimulator of fibrogenesis. Its role in the pathogenesis of human liver cirrhosis is unknown. Therefore, we studied
Autor:
Thomas Knittel, Giuliano Ramadori, Anna Sebestyén, Ilona Kovalszky, Thomas Ambrust, Mónika Gallai
Publikováno v:
Cytokine. 12(10)
Syndecan-1 and syndecan-2-two cell surface heparan sulfate proteoglycans-were described in normal human liver. Proteoglycans can modulate the effect of cytokines, and cytokines can influence the expression of proteoglycans. In the present work the re