Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages

Autor: Arturo González de la Aleja, Cristina Herrero, Mónica Torres-Torresano, Juan Vladimir de la Rosa, Bárbara Alonso, Enrique Capa-Sardón, Ittai B. Muller, Gerrit Jansen, Amaya Puig-Kröger, Miguel A. Vega, Antonio Castrillo, Ángel L. Corbí

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Liver X Receptors (LXR) control cholesterol metabolism and exert anti-inflammatory actions but their contribution to human macrophage polarization remains unclear. The LXR pathway is enriched in pro-inflammatory macrophages from rheumatoid arthritis

Externí odkaz: https://doaj.org/article/74a9cd2489134bd39bba68edb1a38025

Author Correction: Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses

Autor: Aránzazu Cruz-Adalia, Guillermo Ramirez-Santiago, Jesús Osuna-Pérez, Mónica Torres-Torresano, Virgina Zorita, Ana Martínez-Riaño, Viola Boccasavia, Aldo Borroto, Gloria Martínez del Hoyo, José María González-Granado, Balbino Alarcón, Francisco Sánchez-Madrid, Esteban Veiga

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)

The original version of this Article contained an error in the spelling of the author José María González-Granado, which was incorrectly given as José María Gozález-Granado. This has now been corrected in both the PDF and HTML versions of the A

Externí odkaz: https://doaj.org/article/9a212cc615f44447aff861fe1117a5d2

LXR nuclear receptors prompt a pro-inflammatory gene and functional profile in human macrophages

Autor: Amaya Puig-Kröger, Bárbara Alonso, Antonio Castrillo, Arturo González de la Aleja, Miguel A. Vega, Mónica Torres-Torresano, Juan Vladimir de la Rosa, Angel L. Corbí, Enrique Capa-Sardón

Liver X Receptors (LXR) control cholesterol metabolism and exert anti-inflammatory actions in activated macrophages. However, their contribution to human macrophage polarization in the absence of pathogenic stimuli remains unclear. In fact, the LXR p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e6dccbcad9f1eba0f5a89685bf60d6c
https://doi.org/10.21203/rs.3.rs-169946/v1

Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses

Autor: Jesús Osuna-Pérez, Mónica Torres-Torresano, Aldo Borroto, Esteban Veiga, Aranzazu Cruz-Adalia, Balbino Alarcón, José María González-Granado, Virgina Zorita, Ana Martínez-Riaño, Francisco Sánchez-Madrid, Viola Boccasavia, Guillermo Ramirez-Santiago, Gloria Martínez del Hoyo

Publikováno v: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname

Bacterial phagocytosis and antigen cross-presentation to activate CD8 T cells are principal functions of professional antigen presenting cells. However, conventional CD4 T cells also capture and kill bacteria from infected dendritic cells in a proces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdcbbf2552b727aa45346c96d2e90306
http://europepmc.org/articles/PMC5691066

Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge

Autor: Guillermo Ramirez-Santiago, Carlos Oscar S. Sorzano, Eva Pereiro, Giulia Morlino, Javier Robles-Valero, Francisco Sánchez-Madrid, Manuel Pérez-Martínez, Francisco Javier Chichón, Airen Zaldivar, Diego Megías, Mónica Torres-Torresano, Aranzazu Cruz-Adalia, Esteban Veiga, José L. Carrascosa, Andrea Sorrentino

Publikováno v: Europe PubMed Central
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Lymphocyte migration, which is essential for effective immune responses, belongs to the so-called amoeboid migration. The lymphocyte migration is up to 100 times faster than between mesenchymal and epithelial cell types. Migrating lymphocytes are hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc81faa2ed183bead69f491f10b5d6f
http://hdl.handle.net/20.500.12614/392