Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5

Autor: Pilar López-Cotarelo, Juan Martín-Caballero, Juan Miguel Redondo, Marta Riera-Borrull, Elena Bosch, Juana M. Flores, Cristina López-Rodríguez, Jose Aramburu, Sara Martínez-Martínez, José Luis Rodríguez-Fernández, Hector Huerga Encabo, Mónica Tellechea, Lucía Quintana-Gallardo, Maria Buxadé

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC
The Journal of Experimental Medicine

25 p.-5 fig.-5 fig. supl.-2 tab. supl.
MHCII in antigen-presenting cells (APCs) is a key regulator of adaptive immune responses. Expression of MHCII genes is controlled by the transcription coactivator CIITA, itself regulated through cell type-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475b93d2b1c9158961b29b211c0d27d7
https://doi.org/10.1084/jem.20180314