Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mónica S. Montesinos"'
Autor:
Priyadharishini Veeraraghavan, Matthias Lübbert, Toshihisa Ohtsuka, Tamara Radulovic, Samuel M. Young, Debbie Guerrero-Given, R. Oliver Goral, Naomi Kamasawa, Mónica S. Montesinos, Connon I. Thomas, Wei Dong, Kevin M Goff
Publikováno v:
J Physiol
Key points CAST/ELKS are positive regulators of presynaptic growth and are suppressors of active zone expansion at the developing mouse calyx of Held. CAST/ELKS regulate all three CaV 2 subtype channel levels in the presynaptic terminal and not just
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbbaf6640fc0519ff90914aad47530e
https://doi.org/10.1113/jp279736
https://doi.org/10.1113/jp279736
Autor:
Sarah-eve Lemay, Mónica S Montesinos, Yann Grobs, Tsukasa Shimauchi, Sandra Breuils Bonnet, Sandra Martineau, Xinqiang Huang, James E Dowling, Min Lu, Adrian S Ray, Roxane Paulin, François Potus, Steeve Provencher, Olivier BOUCHERAT, Sebastien Bonnet
Publikováno v:
Circulation. 144
Pulmonary arterial hypertension (PAH) is characterized by progressive obstruction and decreased compliance of pulmonary arteries (PA), leading to right ventricular (RV) failure and premature death. It is now recognized that, like cancer cells, PA smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d752ada9a01b24400813bfc0d8501b2c
https://doi.org/10.1161/circ.144.suppl_1.10717
https://doi.org/10.1161/circ.144.suppl_1.10717
Autor:
Mónica S. Montesinos, Lan Nguyen, Yiming Zhou, Anna Greka, Abbe R. Clark, Jamie L. Marshall, Haiqi Chen, Fei Chen
Publikováno v:
Am J Pathol
The health of the kidney filtration barrier requires communication among podocytes, endothelial cells, and mesangial cells. Disruption of these cell-cell interactions is thought to contribute to disease progression in chronic kidney diseases (CKDs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12c8e1647be1957f7856ac9b3c0c2d5
https://pubmed.ncbi.nlm.nih.gov/34861215
https://pubmed.ncbi.nlm.nih.gov/34861215
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:155-159
The transient receptor potential cation channel 5 (TRPC5) has been previously shown to affect podocyte survival in the kidney. As such, inhibitors of TRPC5 are interesting candidates for the treatment of chronic kidney disease (CKD). Herein, we repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1b949de0871d165eeb38ad10602aaf
https://doi.org/10.1016/j.bmcl.2018.12.007
https://doi.org/10.1016/j.bmcl.2018.12.007
Autor:
Ayshwarya Subramanian, Astrid Weins, Jamie L. Marshall, Elizabeth J. Grinkevich, Julia Waldman, Rosenblatt-Rosen O, Maria Alimova, Lan T. Nguyen, Fan Zhang, Yanfang Zhou, Purnell J, Jillian L. Shaw, Anna Greka, Slyper M, Steven L. Chang, Aviv Regev, Ayan Ghoshal, Alexandra-Chloé Villani, Katherine A. Vernon, Dubinsky D, Mónica S. Montesinos, Heller K, Danielle Dionne, Mike Cuoco, Sturner Sh
Mouse models are a tool for studying the mechanisms underlying complex diseases; however, differences between species pose a significant challenge for translating findings to patients. Here, we used single-cell transcriptomics and orthogonal validati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48d5b09333d97e76b2d383fafd4bf366
https://doi.org/10.1101/2021.05.30.446342
https://doi.org/10.1101/2021.05.30.446342
Autor:
Ayshwarya Subramanian, Katherine A. Vernon, Yiming Zhou, Jamie L. Marshall, Maria Alimova, Carlos Arevalo, Fan Zhang, Michal Slyper, Julia Waldman, Monica S. Montesinos, Danielle Dionne, Lan T. Nguyen, Michael S. Cuoco, Dan Dubinsky, Jason Purnell, Keith Keller, Samuel H. Sturner, Elizabeth Grinkevich, Ayan Ghoshal, Amanda Kotek, Giorgio Trivioli, Nathan Richoz, Mary B. Humphrey, Isabella G. Darby, Sarah J. Miller, Yingping Xu, Astrid Weins, Alexandra Chloe-Villani, Steven L. Chang, Matthias Kretzler, Orit Rosenblatt-Rosen, Jillian L. Shaw, Kurt A. Zimmerman, Menna R. Clatworthy, Aviv Regev, Anna Greka
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114253- (2024)
Summary: Diabetic kidney disease (DKD), the most common cause of kidney failure, is a frequent complication of diabetes and obesity, and yet to date, treatments to halt its progression are lacking. We analyze kidney single-cell transcriptomic profile
Externí odkaz:
https://doaj.org/article/c26ba69a6afe47bdbc7deb8408bb9ad1
Autor:
Anna Greka, Mónica S. Montesinos, Lan Nguyen, Yiming Zhou, Abbe R. Clark, Fei Chen, Jamie L. Marshall, Haiqi Chen
The health of the kidney filtration barrier requires communication between podocytes, endothelial cells and mesangial cells. Disruption of these cell-cell interactions is thought to contribute to disease progression in chronic kidney diseases (CKD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fadfe417223d8b1bed08e8465428c8a8
https://doi.org/10.1101/2020.07.30.229666
https://doi.org/10.1101/2020.07.30.229666
Autor:
Philip Castonguay, Sookyung Kim, Jana Reichardt, John M. Basgen, Moran Dvela-Levitt, Nicolas Wieder, Anna Greka, Eric S. Lander, Frank Dubois, Sigrid Hoffmann, Mónica S. Montesinos, Michael R. Garrett, Abbe R. Clark, Ji Yong Jung, Svetlana Andreeva, Jonas Sieber, Corey R. Hopkins, Eriene Heidi Sidhom, Yiming Zhou, Astrid Weins, Ashley C. Johnson
Publikováno v:
Transplantation
PMC
PMC
Progressive kidney diseases are often associated with scarring of the kidney’s filtration unit, a condition called focal segmental glomerulosclerosis (FSGS). This scarring is due to loss of podocytes, cells critical for glomerular filtration, and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb3ed19e710820e06d2274f10e4748d
https://doi.org/10.1126/science.aal4178
https://doi.org/10.1126/science.aal4178
Autor:
Ricardo Borges, Jesica Diaz, José J. Fernández, Mónica S. Montesinos, R. González-Brito, M. A. Campuzano-Bublitz, José G. Hernández-Jiménez
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 391(1)
Procedures to characterize drugs that can be obtained from plant extracts or combinatorial chemistry are tedious, and they consume considerable resources (e.g., animals) and time. Thus, we have looked for a way to streamline this process. We describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97680e0a03fd46a39058001b9032558a
https://pubmed.ncbi.nlm.nih.gov/29063136
https://pubmed.ncbi.nlm.nih.gov/29063136
Publikováno v:
Methods in Molecular Biology ISBN: 9781493963508
Neuroscience research has been revolutionized by the use of recombinant viral vector technology from the basic, preclinical and clinical levels. Currently, multiple recombinant viral vector types are employed with each having its strengths and weakne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf629c944abfda49000e71a904f121b7
https://doi.org/10.1007/978-1-4939-6352-2_5
https://doi.org/10.1007/978-1-4939-6352-2_5