Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mónica Rupérez"'
Autor:
Raquel Rodrigues-Díez, Jesús Egido, Mónica Rupérez, Alberto Ortiz, Marta Ruiz-Ortega, Juan Rodriguez-Vita, Vanesa Esteban, Sergio Mezzano, Cecile Cartier, Gisselle Carvajal, Elsa Sanchez-Lopez
Publikováno v:
KIDNEY INTERNATIONAL
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Epithelial to mesenchymal transdifferentiation is a novel mechanism that promotes renal fibrosis and here we investigated whether known causes of renal fibrosis (angiotensin II and transforming growth factor beta, TGFbeta) act through this pathway. W
Autor:
María Miana, David Sanz-Rosa, Natalia de las Heras, Jesús Egido, Mónica Rupérez, Victoria Cachofeiro, Vicente Lahera, Sergio Mezzano, Paloma Aragoncillo, Marta Ruiz-Ortega
Publikováno v:
Clínica e Investigación en Arteriosclerosis. 19:232-239
Introduccion El factor de crecimiento de tejido conectivo (CTGF) esta implicado en diversas enfermedades, como la aterosclerosis, la fibrosis de la piel y diversas nefritis experimentales y humanas. Sin embargo, el papel de este factor profibrotico e
Autor:
Luis Miguel Blanco-Colio, Vanesa Esteban, Marta Ruiz-Ortega, Juan José Plaza, Jesús Egido, Juan Rodriguez-Vita, Elsa Sanchez-Lopez, Mónica Rupérez, Raquel Rodrigues-Díez, Gisselle Carvajal
Publikováno v:
Hypertension. 50:377-383
3-hydroxy-3-methylglutaryl (HMG)-coenzyme A (CoA) reductase inhibitors (statins) present beneficial effects in cardiovascular diseases. Angiotensin II (Ang II) contributes to cardiovascular damage through the production of profibrotic factors, such a
Autor:
Sergio Mezzano, Mónica Rupérez, David Sanz-Rosa, Paloma Aragoncillo, Natalia de las Heras, Marta Ruiz-Ortega, Jesús Egido, María Miana, Vicente Lahera, Victoria Cachofeiro
Publikováno v:
Journal of Hypertension. 25:629-638
OBJECTIVE The aim of the present study was to investigate possible inter-relationships between connective tissue growth factor (CTGF) and aldosterone in vascular and renal damage associated with hypertension. METHOD Spontaneously hypertensive rats (S
Autor:
Elsa Sanchez-Lopez, Vanesa Esteban, Jesús Egido, Juan Rodriguez-Vita, Gisselle Carvajal, Marta Ruiz-Ortega, Mónica Rupérez
Publikováno v:
Current Opinion in Nephrology and Hypertension. 15:159-166
We will focus on the recent findings concerning the inflammatory response in vascular and renal tissues caused by hypertension.Angiotensin II is one of the main factors involved in hypertension-induced tissue damage. This peptide regulates the inflam
Autor:
Jesús Egido, Mónica Rupérez, Luis Miguel Blanco-Colio, Elsa Sanchez-Lopez, Juan Rodriguez-Vita, Marta Ruiz-Ortega, Vanesa Esteban, Juan José Plaza
Publikováno v:
Scopus-Elsevier
ResearcherID
Europe PubMed Central
ResearcherID
Europe PubMed Central
The Rho-kinase pathway regulates angiotensin II-induced renal damage Background Angiotensin II (AngII) is a key factor in the pathogenesis of renal damage. AngII via AngII type 1 receptors activates several intracellular signaling systems, including
Autor:
Mónica Rupérez, Vanesa Esteban, Óscar Lorenzo, Jesús Egido, Marta Ruiz-Ortega, Juan José Plaza, Sergio Mezzano
Publikováno v:
The American Journal of Pathology. 163:1937-1947
Connective tissue growth factor (CTGF) has been described as a novel fibrotic mediator. CTGF is overexpressed in several kidney diseases and is induced by different factors involved in renal injury. Angiotensin II (AngII) participates in the pathogen
Autor:
Mónica Rupérez, Vanesa Esteban, Jesús Egido, Sergio Mezzano, Elsa Sanchez López, Juan José Plaza, Marta Ruiz-Ortega, Juan Rodriguez Vita
Publikováno v:
Kidney International. 64:S33-S38
Effect of simultaneous blockade of AT1 and AT2 receptors on the NFκB pathway and renal inflammatory response. Background Angiotensin II (Ang II) is a cytokine that participates in the inflammatory response. The nuclear factor kappa B (NFκB) is invo
Autor:
Yusuke Suzuki, Jesús Egido, Takeshi Sugaya, Óscar Lorenzo, Marta Ruiz-Ortega, Mónica Rupérez, Vanesa Esteban
Publikováno v:
Journal of the American Society of Nephrology. 13:1162-1171
Nuclear factor-kappaB (NF-kappaB) regulates many genes involved in renal pathophysiologic processes. It was previously demonstrated that angiotensin II (AngII) and its amino-terminal degradation product AngIII activate NF-kappaB in mesangial cells. H
Publikováno v:
The American Journal of Pathology. 158:1743-1756
Recent studies have pointed out the implication of angiotensin II (Ang II) in various pathological settings. However, the molecular mechanisms and the AngII receptor (AT) subtypes involved are not fully identified. We investigated whether AngII elici