BabA-mediated adherence of pediatric ulcerogenic H. pylori strains to gastric mucins at neutral and acidic pH

Autor: Macarena P. Quintana-Hayashi, Raquel Rocha, Médea Padra, Anders Thorell, Chunsheng Jin, Niclas G. Karlsson, Mónica Roxo-Rosa, Mónica Oleastro, Sara K. Lindén

Publikováno v: Virulence, Vol 9, Iss 1, Pp 1699-1717 (2018)

Helicobacter pylori infection can result in non-ulcer dyspepsia (NUD), peptic ulcer disease (PUD), adenocarcinoma, and gastric lymphoma. H. pylori reside within the gastric mucus layer, mainly composed of mucins carrying an array of glycan structures

Externí odkaz: https://doaj.org/article/c269037ca8eb4db38f363fca8b8bf9a5

CiliarMove: new software for evaluating ciliary beat frequency helps find novel mutations by a Portuguese multidisciplinary team on primary ciliary dyskinesia

Autor: Pedro Sampaio, Mónica Ferro da Silva, Inês Vale, Mónica Roxo-Rosa, Andreia Pinto, Carolina Constant, Luisa Pereira, Carla M. Quintão, Susana S. Lopes

Publikováno v: ERJ Open Research, Vol 7, Iss 1 (2021)

Evaluation of ciliary beat frequency (CBF) performed by high-speed videomicroscopy analysis (HVMA) is one of the techniques required for the correct diagnosis of primary ciliary dyskinesia (PCD). Currently, due to lack of open-source software, this t

Externí odkaz: https://doaj.org/article/8c133485025541c19f4a8cb53afcdfbb

The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR

Autor: Mónica Roxo-Rosa, Raquel Jacinto, Pedro Sampaio, Susana Santos Lopes

Publikováno v: Biology Open, Vol 4, Iss 11, Pp 1356-1366 (2015)

In autosomal dominant polycystic kidney disease (ADPKD), cyst inflation and continuous enlargement are associated with marked transepithelial ion and fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator (CFTR).

Externí odkaz: https://doaj.org/article/93be5d636e1844989ac288ffaae9e7f8

Singlet Oxygen in Antimicrobial Photodynamic Therapy: Photosensitizer-Dependent Production and Decay in E. coli

Autor: Arménio C. Serra, António Rocha Gonsalves, Mónica Roxo-Rosa, Montserrat Agut, Xin He, Xavier Ragàs, Santi Nonell

Publikováno v: Molecules, Vol 18, Iss 3, Pp 2712-2725 (2013)

Several families of photosensitizers are currently being scrutinized for antimicrobial photodynamic therapy applications. Differences in physical and photochemical properties can lead to different localization patterns as well as differences in singl

Externí odkaz: https://doaj.org/article/85a2344f179f42a39c3b8d08edbebf95

Zebrafish model as a screen to prevent cyst inflation in autosomal dominant polycystic kidney disease

Autor: Raquel Jacinto, Fernando Nolasco, Sara Pestana, Joaquim Calado, Inês Filipa Fernandes de Oliveira, Susana S. Lopes, Mónica Roxo-Rosa

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 16
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International Journal of Molecular Sciences, Vol 22, Iss 9013, p 9013 (2021)

Funding Information: Funding: This work was supported by Sociedade Portuguesa de Nefrologia, iNOVA4Health-UID/Multi/04462/2013 (a program financially supported by Fundação para a Ciência e Tecnolo-gia (FCT)/Ministério da Educação e Ciência, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ec02fe49f513c6aeb5d98ff49bc97e
https://hdl.handle.net/10362/125091