Ex vivo, in situ perfusion protocol for human brain fixation compatible with microscopy, MRI techniques, and anatomical studies

Autor: Ricardo Insausti, Ana María Insausti, Mónica Muñoz López, Isidro Medina Lorenzo, Maria del Mar Arroyo-Jiménez, María Pilar Marcos Rabal, Carlos de la Rosa-Prieto, José Carlos Delgado-González, Javier Montón Etxeberria, Sandra Cebada-Sánchez, Juan Francisco Raspeño-García, María Mercedes Iñiguez de Onzoño, Francisco Javier Molina Romero, Ruth Benavides-Piccione, Silvia Tapia-González, Laura E. M. Wisse, Sadhana Ravikumar, David A. Wolk, Javier DeFelipe, Paul Yushkevich, Emilio Artacho-Pérula

Publikováno v: Frontiers in Neuroanatomy, Vol 17 (2023)

We present a method for human brain fixation based on simultaneous perfusion of 4% paraformaldehyde through carotids after a flush with saline. The left carotid cannula is used to perfuse the body with 10% formalin, to allow further use of the body f

Externí odkaz: https://doaj.org/article/1b9324d823f4443d90ef84bc87595743

Short Practise in Human Body Dissection Benefits Acquisition of the Musculoskeletal System in First Year Medical Students at University of Castilla-La Mancha (Spain)

Autor: Ricardo Insausti, Maria del Mar Ubero, Mónica Muñoz López

Publikováno v: Anatomia. 1:126-133

Dissection in anatomy teaching is key in medicine; however, a debate is underway about whether it complements well a modern curriculum in the digital era. We aimed to determine whether a short add-on dissection practise facilitates learning of the gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::460c14f617a0a36156722c1ee12cde53
https://doi.org/10.3390/anatomia1020013

Born Too Early and Too Small: Higher Order Cognitive Function and Brain at Risk at Ages 8–16

Autor: Marta Córcoles-Parada, Rocio Giménez-Mateo, Victor Serrano-del-Pueblo, Leidy López, Elena Pérez-Hernández, Francisco Mansilla, Andres Martínez, Ignacio Onsurbe, Paloma San Roman, Mar Ubero-Martinez, Jonathan D. Clayden, Chris A. Clark, Mónica Muñoz-López

Publikováno v: Frontiers in Psychology, Vol 10 (2019)

Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear. We conducted a

Externí odkaz: https://doaj.org/article/f8765c4dd67143a1bea34a8702031216

Integrating color deconvolution thresholding and weakly supervised learning for automated segmentation of neurofibrillary tangle and neuropil threads

Autor: Hyung Seok Roh, David J. Irwin, Mónica Muñoz López, Maria Mercedes Iñiguez de Onzoño Martin, Ranjit Ittyerah, Sydney Lim, Madigan L. Bedard, John L. Robinson, Theresa Schuck, Emilio Artacho-Pérula, María del Mar Arroyo Jiménez, María Pilar Marcos Rabal, Francisco Javier Molina Romero, Sandra Cebada Sánchez, José Carlos Delgado González, Carlos de la Rosa-Prieto, Marta Córcoles Parada, Edward B. Lee, Daniel T. Ohm, Laura E. M. Wisse, David A. Wolk, James C. Gee, Ricardo Insausti, Paul A. Yushkevich, Min Chen

Publikováno v: Medical Imaging 2023: Digital and Computational Pathology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9e01cb6831c5962ce25b57e8c526575
https://doi.org/10.1117/12.2651848

A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory

Autor: Mohammad Zaki Bin Ibrahim, Marta Corcoles, Andrea Moreno, Nicola J. Broadbent, Richard G. M. Morris, Anna Padanyi, Lauren Strickland, Mónica Muñoz-López, Elizabeth Begg, Lucas Berend Lumeij, Dorothy Tse, Jose-Maria Carames, Alice I Ayres, Brittany Masatsugu, Theofilos Mazidzoglou, Tomonori Takeuchi, Marco Peters

Publikováno v: Broadbent, N, Lumeij, L, Corcoles-Parada, M, Ayres, A, bin Ibrahim, M Z, Masatsugu, B, Moreno, A, Carames Tejedor, J, Begg, E, Strickland, L, Mazidzoglou, T, Padanyi, A, Munoz, M, Takeuchi, T, Peters, M, Morris, R & Tse, D 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience . https://doi.org/10.1111/ejn.14681
Broadbent, N, Lumeij, L B, Corcoles, M, Ayres, A I, Bin Ibrahim, M Z, Masatsugu, B, Moreno, A, Carames, J M, Begg, E, Strickland, L, Mazidzoglou, T, Padanyi, A, Munoz-Lopez, M, Takeuchi, T, Peters, M, Morris, R G M & Tse, D 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience, vol. 51, no. 7, pp. 1539-1558 . https://doi.org/10.1111/ejn.14681
Takeuchi, T 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience . https://doi.org/10.1111/ejn.14681

A key issue in neurobiological studies of episodic-like memory is the geometric frame of reference in which memory traces of experience are stored. Assumptions are sometimes made that specific protocols favour either allocentric (map-like) or egocent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070daa9e756bde0da8d2f7a70e5932f1
https://pubmed.ncbi.nlm.nih.gov/31944427