Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Mónica Montero Lomelí"'
Autor:
Evandro A. De-Souza, Felipe S. A. Pimentel, Caio M. Machado, Larissa S. Martins, Wagner S. da-Silva, Mónica Montero-Lomelí, Claudio A. Masuda
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 1, Pp 55-61 (2014)
Classic galactosemia is a human autosomal recessive disorder caused by mutations in the GALT gene (GAL7 in yeast), which encodes the enzyme galactose-1-phosphate uridyltransferase. Here we show that the unfolded protein response pathway is triggered
Externí odkaz:
https://doaj.org/article/0d328464420d429e8395af3ccb6fae5a
Autor:
Bruno Leonardo Bozaquel-Morais, Leonie Vogt, Valentina D’Angelo, Raffael Schaffrath, Roland Klassen, Mónica Montero-Lomelí
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 49 (2018)
The protein phosphatase Sit4 has been shown to be required for lipogenesis and resistance against the acetyl-CoA carboxylase inhibitor soraphen A. Since Sit4 is also required for biosynthesis of Elongator dependent tRNA modifications such as 5-methox
Externí odkaz:
https://doaj.org/article/13b57e4a55c642baa2db95a833a248c0
Autor:
Caroline Mota Fernandes, Deveney Dasilva, Maurizio Del Poeta, Claudio A. Masuda, Gabriel S. Matos, Mónica Montero-Lomelí, Juliana B. Madeira
Publikováno v:
Biochim Biophys Acta Mol Cell Biol Lipids
SBF (Swi4/Swi6 Binding Factor) complex is a crucial regulator of G1/S transition in Saccharomyces cerevisiae. Here, we show that SBF complex is required for myriocin resistance, an inhibitor of sphingolipid synthesis. This phenotype was not shared wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ec95d694ab4b58ef9958ae7483453c
https://doi.org/10.1016/j.bbalip.2021.158983
https://doi.org/10.1016/j.bbalip.2021.158983
Autor:
Juan Pablo Pardo, Marco Antonio Juárez Oropeza, Lucero Romero Aguilar, Oscar Ivan Luqueño Bocardo, Mónica Montero Lomelí, Guadalupe Guerra Sánchez
Publikováno v:
Archives of Microbiology. 199:1195-1209
In many organisms, the growth under nitrogen-deprivation or a poor nitrogen source impacts on the carbon flow distribution and causes accumulation of neutral lipids, which are stored as lipid droplets (LDs). Efforts are in progress to find the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c7f6cefc9bbcda9e4f1dff65a9452a
https://doi.org/10.1007/s00203-017-1388-8
https://doi.org/10.1007/s00203-017-1388-8
Autor:
Claudio A. Masuda, Silas Pinto, Antonio Galina, Henrique Camara, Ana Luiza F. V. De-Queiroz, Caio M. Machado, Marcelo A. Mori, Mikaella L. Felix-Formiga, Felipe S. A. Pimentel, Evandro A. De-Souza, Mónica Montero-Lomelí
Publikováno v:
J Biol Chem
In the presence of galactose, lithium ions activate the unfolded protein response (UPR) by inhibiting phosphoglucomutase activity and causing the accumulation of galactose-related metabolites, including galactose-1-phosphate. These metabolites also a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c76e9bba63242f42c098006e521fce8
https://europepmc.org/articles/PMC7086034/
https://europepmc.org/articles/PMC7086034/
Autor:
Laryssa S Messias, Bruno L. Bozaquel-Morais, Gabriel S. Matos, Claudio A. Masuda, Juliana B. Madeira, Mónica Montero-Lomelí
Publikováno v:
FEMS yeast research. 19(3)
In this study, we found that cell cycle arrest induced by alpha-factor mating pheromone (G1), hydroxyurea (S) or nocodazole (G2/M) was associated to increased lipid droplet (LD) content. To identify novel cell cycle genes involved in LD homeostasis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd9db5451b02e0472d05bd35759ab7f
https://pubmed.ncbi.nlm.nih.gov/30985885
https://pubmed.ncbi.nlm.nih.gov/30985885
Publikováno v:
Journal of Visualized Experiments.
The article shows how to implement the LD index assay, which is a sensitive microplate assay to determine the accumulation of triacylglycerols (TAGs) in lipid droplets (LDs). LD index is obtained without lipid extraction. It allows measuring the LDs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99e12fb2b11b288b50fbfb76caa4073
https://doi.org/10.3791/57279
https://doi.org/10.3791/57279
Autor:
Ernesto T. A. Marques, Fernando A. Bozza, Mariana L. Palma, Leonardo Nimrichter, Bruno Douradinha, Daniel Zamith-Miranda, Flaviano S. Martins, Mónica Montero-Lomelí
Publikováno v:
Applied Microbiology and Biotechnology. 99:6563-6570
The probiotic yeast Saccharomyces cerevisiae var boulardii is widely used as a low cost and efficient adjuvant against gastrointestinal tract disorders such as inflammatory bowel disease and treatment of several types of diarrhea, both in humans and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42470264994a7dce8714044cfaf27cd6
https://doi.org/10.1007/s00253-015-6776-x
https://doi.org/10.1007/s00253-015-6776-x
The galactose-induced decrease in phosphate levels leads to toxicity in yeast models of galactosemia
Autor:
Evandro A. De-Souza, Mónica Montero-Lomelí, Felipe S. A. Pimentel, Ana Luiza F. V. De-Queiroz, Caio M. Machado, Fabio M. Gomes, Claudio A. Masuda, Guilherme Firmino Silva
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1863(6)
Classic galactosemia is an inborn error of metabolism caused by deleterious mutations in the GALT gene. A number of evidences indicate that the galactose-1-phosphate accumulation observed in patient cells is a cause of toxicity in this disease. Never
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8167f1d4c72f46e7eea7357840b6261
https://pubmed.ncbi.nlm.nih.gov/28213126
https://pubmed.ncbi.nlm.nih.gov/28213126
Autor:
Juliana B. Madeira, Mónica Montero-Lomelí, Thiago Pacheco-Rosa, Claudio A. Masuda, Thiago Motta Venâncio, Bruno L. Bozaquel-Morais
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0169682 (2017)
PLoS ONE, Vol 12, Iss 1, p e0169682 (2017)
Acetyl-CoA carboxylase (Acc1p) is a key enzyme in fatty acid biosynthesis and is essential for cell viability. To discover new regulators of its activity, we screened a Saccharomyces cerevisiae deletion library for increased sensitivity to soraphen A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce4f1406aba3fb8754485ca5c61b6ad
https://pubmed.ncbi.nlm.nih.gov/28076367
https://pubmed.ncbi.nlm.nih.gov/28076367