Výsledky vyhledávání - "Mónica García-Solache"

Akademický článek

Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains

Autor: Paul Ugalde Silva, Charlene Desbonnet, Louis B. Rice, Mónica García-Solache

Publikováno v: mBio, Vol 15, Iss 12 (2024)

ABSTRACT Resistance to ampicillin and imipenem in Enterococcus faecalis is infrequent. However, the evolution of resistance can occur through prolonged antibiotic exposure during the treatment of chronic infections. In this study, we conducted a long

Externí odkaz: https://doaj.org/article/1ed2e69d21f54318a48a0457c8d554b1

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Meropenem plus Ceftaroline Is Active against Enterococcus faecalis in an

Autor: Jaclyn A, Cusumano, Kathryn E, Daffinee, Emily C, Piehl, Mónica, García-Solache, Charlene, Desbonnet, Louis B, Rice, Kerry L, LaPlante

Publikováno v: Antimicrob Agents Chemother

The standard of care for serious Enterococcus faecalis infections is ampicillin plus ceftriaxone. Ampicillin’s inconvenient dosing schedule, drug instability, allergy potential, along with ceftriaxone’s high risk for Clostridioides difficile infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::323dda75cb421356d768a9778d43e14a
https://pubmed.ncbi.nlm.nih.gov/36154173

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Penicillin-Binding Proteins and Alternative Dual-Beta-Lactam Combinations for Serious Enterococcus faecalis Infections with Elevated Penicillin MICs

Autor: Jaclyn A. Cusumano, Kathryn E. Daffinee, Paul Ugalde-Silva, Wolfgang Peti, Michel Arthur, Charlene Desbonnet, Louis B. Rice, Kerry L. LaPlante, Mónica García-Solache

Publikováno v: Antimicrobial Agents and Chemotherapy. 67

Ampicillin-ceftriaxone has become a first-line therapy for Enterococcus faecalis endocarditis. We characterized the penicillin-binding protein (PBP) profiles of various E. faecalis strains and tested for synergy to better inform beta-lactam options f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a4ecd5aae0deffa803d2179c8fe9d48
https://doi.org/10.1128/aac.00871-22

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Meropenem plus Ceftaroline Is Active against Enterococcus faecalis in an In Vitro Pharmacodynamic Model Using Humanized Dosing Simulations

Autor: Jaclyn A. Cusumano, Kathryn E. Daffinee, Emily C. Piehl, Mónica García-Solache, Charlene Desbonnet, Louis B. Rice, Kerry L. LaPlante

Publikováno v: Antimicrobial Agents and Chemotherapy. 66

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::612f6904dcb20fd5e27b1ee242b894da
https://doi.org/10.1128/aac.00426-22

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Ready-to-eat dairy products as a source of multidrug-resistant Enterococcus strains: Phenotypic and genotypic characteristics

Autor: Mónica García-Solache, Wioleta Chajęcka-Wierzchowska, Anna Zadernowska

Publikováno v: Journal of dairy science. 103(5)

The enterococci are ubiquitous bacteria able to colonize the human and animal gastrointestinal tracts and fresh and fermented food products. Their highly plastic genome allows Enterococcus spp. to gain resistance to multiple antibiotics, making infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028c10e864fde2ae2bac2ff174e1c706
https://pubmed.ncbi.nlm.nih.gov/32197843

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Draft Genome Sequence of Vancomycin-Susceptible, Ampicillin-Intermediate Enterococcus faecium Strain D344RRF

Autor: Mónica García-Solache, Louis B. Rice

Publikováno v: Genome Announcements

Enterococcus faecium is an important nosocomial pathogen, causing a substantial health burden due to high resistance to antibiotics and its ability to colonize the gastrointestinal tract. Here, we present the draft genome of vancomycin-susceptible, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199da413ff3fdaba95eda015b3b367ea
https://pubmed.ncbi.nlm.nih.gov/27151809

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Genome Sequence of the Multiantibiotic-Resistant Enterococcus faecium Strain C68 and Insights on the pLRM23 Colonization Plasmid

Autor: Louis B. Rice, Mónica García-Solache

Publikováno v: Genome Announcements

Enterococcus faecium infections are a rising concern in hospital settings. Vancomycin-resistant enterococci colonize the gastrointestinal tract and replace nonresistant strains, complicating the treatment of debilitated patients. Here, we present a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5734d561a8c3a92c3cfe374076238fe
https://pubmed.ncbi.nlm.nih.gov/27151808

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Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of β-Lactam and Vancomycin Resistance in Enterococcus faecium

Autor: Louis B. Rice, Francois Lebreton, Michael S. Gilmore, Mónica García-Solache, James D. Whiteaker, Robert E. McLaughlin

Publikováno v: Antimicrobial Agents and Chemotherapy

The transfer of DNA between Enterococcus faecium strains has been characterized both by the movement of well-defined genetic elements and by the large-scale transfer of genomic DNA fragments. In this work, we report on the whole-genome analysis of tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d828575dbf1cbda9c167409ead18ad7f
https://pubmed.ncbi.nlm.nih.gov/27431230

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A systematic analysis of the gap gene system in the moth midge Clogmia albipunctata

Autor: Michael Akam, Johannes Jaeger, Mónica García-Solache

Publikováno v: Developmental Biology. 344(1):306-318

The segmentation gene hierarchy of Drosophila melanogaster represents one of the best understood of the gene networks that generate pattern during embryogenesis. Some components of this network are ancient, while other parts of the network have evolv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca40841c66234736c0342f086f13efe

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Involvement of the Eukaryote-Like Kinase-Phosphatase System and a Protein That Interacts with Penicillin-Binding Protein 5 in Emergence of Cephalosporin Resistance in Cephalosporin-Sensitive Class A Penicillin-Binding Protein Mutants in Enterococcus faecium

Autor: Paul M. Dunman, Amelia Tait-Kamradt, Louis B. Rice, Jeffrey J. Coleman, Michel Arthur, Charlene Desbonnet, Mónica García-Solache

Publikováno v: mBio
mBio, American Society for Microbiology, 2016, 7 (2), pp.e02188-15. ⟨10.1128/mBio.02188-15⟩
mBio, American Society for Microbiology, 2016, 7 (2), pp.e02188-15. 〈10.1128/mBio.02188-15〉
mBio, 2016, 7 (2), pp.e02188-15. ⟨10.1128/mBio.02188-15⟩
mBio, Vol 7, Iss 2, p e02188-15 (2016)
mBio, Vol 7, Iss 2 (2016)

The intrinsic resistance of Enterococcus faecium to ceftriaxone and cefepime (here referred to as “cephalosporins”) is reliant on the presence of class A penicillin-binding proteins (Pbps) PbpF and PonA. Mutants lacking these Pbps exhibit cephalo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921950e65801de3a8f7974649da10c63
https://hal.sorbonne-universite.fr/hal-01344141/document

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