Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mónica Díaz-Gavilán"'
Autor:
Victoriano Corpas-López, Victoriano Díaz-Sáez, Francisco Morillas-Márquez, Francisco Franco-Montalbán, Mónica Díaz-Gavilán, Julián López-Viota, Margarita López-Viota, José Antonio Gómez-Vidal, Joaquina Martín-Sánchez
Publikováno v:
Animals, Vol 12, Iss 19, p 2700 (2022)
Canine leishmaniosis is a challenge in veterinary medicine and no drug to date has achieved parasite clearance in dogs. Histone deacetylase inhibitors are a drug class widely used in cancer chemotherapy. We have successfully used O-alkyl hydroxamates
Externí odkaz:
https://doaj.org/article/e2e7a3f31bac45138ed58707bc3b46bf
Autor:
Victoriano, Corpas-López, Victoriano, Díaz-Sáez, Francisco, Morillas-Márquez, Francisco, Franco-Montalbán, Mónica, Díaz-Gavilán, Julián, López-Viota, Margarita, López-Viota, José Antonio, Gómez-Vidal, Joaquina, Martín-Sánchez
Publikováno v:
Animals : an open access journal from MDPI. 12(19)
Canine leishmaniosis is a challenge in veterinary medicine and no drug to date has achieved parasite clearance in dogs. Histone deacetylase inhibitors are a drug class widely used in cancer chemotherapy. We have successfully used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6eab2bcdd312eb3dbddcee40cbc8dad0
https://pubmed.ncbi.nlm.nih.gov/36230441
https://pubmed.ncbi.nlm.nih.gov/36230441
Autor:
Yudibeth Sixto-López, Margarita López-Viota, Sonia Panadero-Fajardo, Mavys Tabraue-Chávez, Mónica Díaz-Gavilán, José Pérez del Palacio, José Correa-Basurto, Joaquina Martín-Sánchez, Mercedes de la Cruz, Fernando Alves de Lima Franco, Nuria de Pedro, José F. Domínguez-Seglar, Victoriano Corpas-López, Francisco Franco-Montalban, Francisco Morillas-Márquez, Julian Lopez-Viota, José A. Gómez-Vidal
Publikováno v:
Journal of Medicinal Chemistry. 63:5734-5751
Leishmania (L.) infantum causes visceral, cutaneous, and mucosal leishmaniasis in humans and canine leishmaniasis in dogs. Herein, we describe that O-alkyl hydroxamate derivatives displayed potent and selective in vitro activity against the amastigot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f935cdb8a5edc65d3b64ce1744a278
https://doi.org/10.1021/acs.jmedchem.9b02016
https://doi.org/10.1021/acs.jmedchem.9b02016
Autor:
Margarita López-Viota, Francisco Morillas-Márquez, Victoriano Corpas-López, Joaquina Martín-Sánchez, José Pérez del Palacio, Nuria de Pedro, Efres Belmonte-Reche, José A. Gómez-Vidal, Julián López-Viota, Mónica Díaz-Gavilán, Gemma Merino-Espinosa, Francisco Franco-Montalban
Publikováno v:
Pharmacological Research. 139:375-383
There is currently no satisfactory treatment for visceral leishmaniasis; the disease is thus in desperate need of novel drugs. The ideal candidate should be effective, safe, affordable, and administered via the oral route. Histone deacetylases (HDACs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd67def1d6da6f2d29906c6f0146799
https://doi.org/10.1016/j.phrs.2018.11.039
https://doi.org/10.1016/j.phrs.2018.11.039
Autor:
José A. Gómez-Vidal, Maria Dolores Moya-Garzon, Joaquín Altarejos, Alfonso Alejo-Armijo, Sofía Salido, Miguel X. Fernandes, Mónica Díaz-Gavilán, Juan R. Rodriguez-Madoz, Eduardo Salido
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 74, p 74 (2021)
Journal of Personalized Medicine, Vol 11, Iss 74, p 74 (2021)
Primary hyperoxalurias (PHs) are a group of inherited alterations of the hepatic glyoxylate metabolism. PHs classification based on gene mutations parallel a variety of enzymatic defects, and all involve the harmful accumulation of calcium oxalate cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a13ef3bad0af5f03ad5aca67ead7e3
https://pubmed.ncbi.nlm.nih.gov/33513899
https://pubmed.ncbi.nlm.nih.gov/33513899
Autor:
José A. Gómez-Vidal, Mónica Díaz-Gavilán, Francisco Franco-Montalban, Maria Dolores Moya-Garzon, Eduardo Salido, Manuela Romera, Cristina Martín Higueras, Pablo Peñalver, Miguel X. Fernandes
Publikováno v:
Journal of medicinal chemistry. 61(16)
Primary hyperoxaluria type 1 (PH1) is a rare life-threatening genetic disease related to glyoxylate metabolism and characterized by accumulation of calcium oxalate crystals. Current therapies involve hepatic and/or renal transplantation, procedures t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a61e75a92a3e86b052f9e3324e29b2d
https://pubmed.ncbi.nlm.nih.gov/30028141
https://pubmed.ncbi.nlm.nih.gov/30028141
Autor:
José A. Gómez-Vidal, Mónica Díaz-Gavilán, José F. Domínguez-Seglar, Javier Galindo-Ángel, Antonio Occorso, Ana M. Pérez-López, Juan A. Tamayo, Dávir González-Calderón
Publikováno v:
Synlett. 25:2319-2322
Octaarginine has been described as a molecular transporter. We report a useful synthesis of orthogonally protected l -octaarginine by using a method based on a microencapsulated palladium catalyst. Known palladium-based methods for allyl ester deprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e083dcb528e1638dc525756ce6df892
https://doi.org/10.1055/s-0034-1378379
https://doi.org/10.1055/s-0034-1378379
Autor:
Joaquín M. Campos, Antonio Martínez-Amat, Octavio Caba, Ana Conejo-García, Antonia Aránega, Fernando Rodríguez-Serrano, Mónica Díaz-Gavilán, Juan A. Marchal, Miguel A. Gallo, Raúl Ortiz, Pablo J. Álvarez
Publikováno v:
European Journal of Medicinal Chemistry. 50:376-382
Advance in the knowledge of molecular biology has thrown light on many aspects of apoptosis regulation mechanisms. This has allowed a change in anti-cancer therapy trends, from classic cytotoxic strategies to the development of new non-harmful therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a823e31a9cbf70462f2e2be7097750
https://doi.org/10.1016/j.ejmech.2012.02.017
https://doi.org/10.1016/j.ejmech.2012.02.017
Autor:
Joaquín M. Campos, Juan A. Marchal, Mónica Díaz-Gavilán, Fernando Rodríguez-Serrano, Antonia Aránega, Octavio Caba, Houria Boulaiz, Miguel A. Gallo
Publikováno v:
European Journal of Medicinal Chemistry. 46:3802-3809
Completing a SAR study, a series of ( RS )-6-substituted-7- or 9-(1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-7 H or 9 H -purines was previously prepared. The most potent antiproliferative agent against the MCF-7 adenocarcinoma cell line that belongs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065dd023d987c79fe4d402376581af13
https://doi.org/10.1016/j.ejmech.2011.05.047
https://doi.org/10.1016/j.ejmech.2011.05.047
Autor:
Mónica Díaz-Gavilán, Joaquín M. Campos, Ana Conejo-García, Maria del Carmen Nunez, Antonio Espinosa, Miguel A. Gallo, Olga Cruz-Lopez
Publikováno v:
Current Medicinal Chemistry. 15:2614-2631
Having previously reported the synthesis and anticancer activities of cyclic 5-fluorouracil (5-FU) O,N-acetalic compounds, the decision was made to change 5-FU for uracil (U), with the prospect of finding an antiproliferative agent endowed with a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414276842c7870107e22739c9aa16a33
https://doi.org/10.2174/092986708785909021
https://doi.org/10.2174/092986708785909021