Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy

Autor: Doménica Tarallo, Jennyfer Martínez, Alejandro Leyva, Amy Mónaco, Carolina Perroni, Marcos Tassano, Juan Pablo Gambini, Mónica Cappetta, Rosario Durán, María Moreno, Celia Quijano

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)

Abstract Cellular senescence is a therapy endpoint in melanoma, and the senescence-associated secretory phenotype (SASP) can affect tumor growth and microenvironment, influencing treatment outcomes. Metabolic interventions can modulate the SASP, and

Externí odkaz: https://doaj.org/article/8fd69163ea73458c852c04b1cde7b6ad

Ancestría genética y estratificación social en Montevideo, Uruguay

Autor: Mónica Sans, Gonzalo Figueiro, Carolina Bonilla, Bernardo Bertoni, Mónica Cappetta, Nora Artagaveytia, Elizabeth Ackermann, Patricia Mut, Pedro C. Hidalgo

Publikováno v: Revista Argentina de Antropología Biológica, Vol 23, Iss 1 (2020)

Diversos estudios genéticos han demostrado que la población uruguaya es trihíbrida, formada por europeo/mediterráneos, indígenas y africanos, cuyo aporte varía en distintas regiones del país. Pese a que Montevideo es la capital de la Repúblic

Externí odkaz: https://doaj.org/article/cbc892adcbab4592a0177fb80cf8781b

Discovery of novel DNA methylation biomarkers for non-invasive sporadic breast cancer detection in the Latino population

Autor: Lucía Brignoni, Mónica Cappetta, Nora Artagaveytia, Manel Esteller, Carolina Bonilla, Miguel López, Bernardo Bertoni, María Berdasco, Lucía Fernández

Publikováno v: Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Molecular Oncology, Vol 15, Iss 2, Pp 473-486 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Molecular Oncology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya

Epigenetic alterations are already being incorporated as robust biomarkers for prediction of cancer risk. Despite this success, validation in specific populations with different genetic backgrounds and variable lifestyle and environmental exposures i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fbd74d179d5dd1e5cd1ad4cb3e5b35
https://hdl.handle.net/2072/445021

Author response for 'Discovery of novel DNA methylation biomarkers for non‐invasive sporadic breast cancer detection in the Latino population'

Autor: Mónica Cappetta, Carolina Bonilla, Nora Artagaveytia, Lucía Fernández, Miguel Lopez, Manel Esteller, Bernardo Bertoni, María Berdasco, Lucía Brignoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29e27923a48172945959a1c62cd9e5cb
https://doi.org/10.1002/1878-0261.12842/v2/response1

Epigenetic Alterations: The Relation Between Occupational Exposure and Biological Effects in Humans

Autor: Juliana da Silva, Mónica Cappetta, Vivian Francília Silva Kahl

Publikováno v: RNA Technologies ISBN: 9783030147914

Exposome encompass the totality of human environmental exposures, providing a lifelong exposure history and complementing the genome. One of its domains is a specific external environment, which includes occupational exposure. Over the last decades,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abafa7a792366f125ca4e0033cd3a34d
https://doi.org/10.1007/978-3-030-14792-1_11