Zobrazeno 1 - 3
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pro vyhledávání: '"Mónica Alfonso-Núñez"'
Autor:
Daniel C Maddison, Mónica Alfonso-Núñez, Aisha M Swaih, Carlo Breda, Susanna Campesan, Natalie Allcock, Anna Straatman-Iwanowska, Charalambos P Kyriacou, Flaviano Giorgini
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009129 (2020)
The enzyme kynurenine 3-monooxygenase (KMO) operates at a critical branch-point in the kynurenine pathway (KP), the major route of tryptophan metabolism. As the KP has been implicated in the pathogenesis of several human diseases, KMO and other enzym
Externí odkaz:
https://doaj.org/article/aea42986a97645b6b78125a87fbcc1a9
Autor:
Flaviano Giorgini, Aisha M. Swaih, Anna Straatman-Iwanowska, Charalambos P. Kyriacou, Daniel C. Maddison, Mónica Alfonso-Núñez, Susanna Campesan, Natalie Allcock, Carlo Breda
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 11, p e1009129 (2020)
PLoS Genetics, Vol 16, Iss 11, p e1009129 (2020)
The enzyme kynurenine 3-monooxygenase (KMO) operates at a critical branch-point in the kynurenine pathway (KP), the major route of tryptophan metabolism. As the KP has been implicated in the pathogenesis of several human diseases, KMO and other enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd690b874d8039bfeb5a7717f001153
http://europepmc.org/articles/PMC7654755
http://europepmc.org/articles/PMC7654755
Publikováno v:
Pathogenic mechanisms.
Background Huntington’s disease (HD) is caused by the expansion of a CAG trinucleotide repeat in the huntingtin (HTT) gene. Beyond a critical disease-causing threshold, the number of repeats correlates strongly with severity of disease, though a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398515582abd85e05ec6cb63bcc5cd07
https://doi.org/10.1136/jnnp-2018-ehdn.45
https://doi.org/10.1136/jnnp-2018-ehdn.45