Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mónica Alejandra, Costas"'
RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition
Autor:
María Fernanda Rubio, María Cecilia Lira, Francisco Damián Rosa, Adrían Dario Sambresqui, María Cecilia Salazar Güemes, Mónica Alejandra Costas
Publikováno v:
Cancer Cell International, Vol 17, Iss 1, Pp 1-17 (2017)
Abstract Background RAC3 coactivator overexpression has been implicated in tumorigenesis, contributing to inhibition of apoptosis and autophagy. Both mechanisms are involved in resistance to treatment with chemotherapeutic agents. The aim of this stu
Externí odkaz:
https://doaj.org/article/61f4631d344e46d0b06ebff5714c4736
Autor:
Cecilia Viviana Alvarado, María Fernanda Rubio, Pablo Nicolas Fernández Larrosa, Laura Carolina Panelo, Pablo Javier Azurmendi, Marina Ruiz Grecco, Giselle Astrid Martínez-Nöel, Mónica Alejandra Costas
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 450-457 (2014)
RAC3 is a coactivator of glucocorticoid receptor and nuclear factor-κB (NF-κB) that is usually over-expressed in tumors and which also has important functions in the immune system. We investigated the role of the inflammatory response in the contro
Externí odkaz:
https://doaj.org/article/1f0b0417a8c6465f853a0c3f31924b5a
Autor:
Alejandra Graciela, Palma, Mileni, Soares Machado, María Cecilia, Lira, Francisco, Rosa, María Fernanda, Rubio, Gabriela, Marino, Basilio Aristidis, Kotsias, Mónica Alejandra, Costas
Publikováno v:
Cellular oncology (Dordrecht). 44(3)
CFTR mutations not only cause cystic fibrosis, but also increase the risk of colorectal cancer. A putative role of CFTR in colorectal cancer patients without cystic fibrosis has so far, however, not been investigated. RAC3 is a nuclear receptor coact