Výsledky vyhledávání - "Méziane Ibazizène"

Akademický článek

Multimodal evaluation of hypoxia in brain metastases of lung cancer and interest of hypoxia image-guided radiotherapy

Autor: Aurélien Corroyer-Dulmont, Samuel Valable, Jade Fantin, Laurent Chatre, Jérôme Toutain, Sylvain Teulier, Céline Bazille, Elise Letissier, Jérôme Levallet, Didier Divoux, Méziane Ibazizène, Stéphane Guillouet, Cécile Perrio, Louisa Barré, Sébastien Serres, Nicola R. Sibson, Françoise Chapon, Guénaëlle Levallet, Myriam Bernaudin

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

Abstract Lung cancer patients frequently develop brain metastases (BM). Despite aggressive treatment including neurosurgery and external-radiotherapy, overall survival remains poor. There is a pressing need to further characterize factors in the micr

Externí odkaz: https://doaj.org/article/ee453995c9c84f099bc393bb803de626

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Akademický článek

64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study

Autor: Elodie A. Pérès, Jérôme Toutain, Louis-Paul Paty, Didier Divoux, Méziane Ibazizène, Stéphane Guillouet, Louisa Barré, Aurélien Vidal, Michel Cherel, Mickaël Bourgeois, Myriam Bernaudin, Samuel Valable

Publikováno v: EJNMMI Research, Vol 9, Iss 1, Pp 1-15 (2019)

Abstract Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu (64Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However, various controversial studies highlighted potential pitfalls that may disable its use a

Externí odkaz: https://doaj.org/article/e90ccfff5e35401c9889fec7302f79d4

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Evaluation of Specific Binding of [11C]RTI-97 to Kappa Opioid Receptor by Autoradiography and PET Imaging in Rat

Autor: Fabien Fillesoye, Florence Noble, Nicolas Marie, Méziane Ibazizène, Cécile Perrio

Publikováno v: ACS Medicinal Chemistry Letters. 12:1739-1744

Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases and to help the development of drugs especially for psychiatric disorders such as depression, anxiety, and addiction. The potent and selec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aef9880e7125efaa5a0967d96fcb1b7
https://doi.org/10.1021/acsmedchemlett.1c00369

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64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study

Autor: Louis-Paul Paty, Samuel Valable, Mickaël Bourgeois, Aurélien Vidal, Stéphane Guillouet, Méziane Ibazizène, Jérôme Toutain, Myriam Bernaudin, Louisa Barré, Didier Divoux, Michel Chérel, Elodie A. Pérès

Publikováno v: EJNMMI Research
EJNMMI Research, SpringerOpen, 2019, 9 (114), ⟨10.1186/s13550-019-0586-6⟩
EJNMMI Research, Vol 9, Iss 1, Pp 1-15 (2019)
EJNMMI Research, 2019, 9 (114), ⟨10.1186/s13550-019-0586-6⟩

Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu (64Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However, various controversial studies highlighted potential pitfalls that may disable its use as a selec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f658035090bdd13a6aa1626c413cc0e
https://hal-normandie-univ.archives-ouvertes.fr/hal-02409461

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18F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients

Autor: Jean-Pierre Pelage, Sylvain Chantepie, Alain Manrique, Anne-Claire Gac, Stéphane Guillouet, Méziane Ibazizène, Michel Leporrier, Thomas Carlier, Françoise Kraeber-Bodéré, Jean-Pierre Vilque, Gandhi Damaj, Louisa Barré, Caroline Bodet-Milin, Narinée Hovhannisyan, Emilie Reboursiere

Publikováno v: Journal of Nuclear Medicine
Journal of Nuclear Medicine, Society of Nuclear Medicine, 2018, 59 (9), pp.1380-1385. ⟨10.2967/jnumed.117.206920⟩
Journal of Nuclear Medicine, 2018, 59 (9), pp.1380-1385. ⟨10.2967/jnumed.117.206920⟩

CERVOXY/LDM-TEP COLL; International audience; This was the first-in-humans clinical study of 18F-fludarabine, which is a radiopharmaceutical for PET imaging in lymphoma, for which many issues remain controversial with the standard radiotracer 18F-FDG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a1c9194d1385e416bdce3eba041e22
https://doi.org/10.2967/jnumed.117.206920

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Chemical Delivery System of MIBG to the Central Nervous System: Synthesis

Autor: Fabienne, Gourand, Delphine, Patin, Axelle, Henry, Méziane, Ibazizène, Martine, Dhilly, Fabien, Fillesoye, Olivier, Tirel, Mihaela-Liliana, Tintas, Cyril, Papamicaël, Vincent, Levacher, Louisa, Barré

Publikováno v: ACS medicinal chemistry letters. 10(3)

[Image: see text] The norepinephrine transporter (NET) plays an important role in neurotransmission and is involved in a multitude of psychiatric and neurodegenerative diseases. [(123)I/(131)I]meta-iodobenzylguanidine (MIBG) is a widely used radiotra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf40af931f5d9d1a9a198f894740cb76
https://pubmed.ncbi.nlm.nih.gov/30891139

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[ 18 F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [ 18 F]FDG in human xenograft models

Autor: Jérôme Toutain, Stéphane Guillouet, Benoît Plancoulaine, Narinée Hovhannisyan, Louisa Barré, Fabienne Gourand, Méziane Ibazizène, Fabien Fillesoye, Samuel Valable

Publikováno v: Theranostics
Theranostics, 2018, 8 (16), pp.4563-4573. ⟨10.7150/thno.26754⟩
Theranostics, Ivyspring International Publisher, 2018, 8 (16), pp.4563-4573. ⟨10.7150/thno.26754⟩

This paper investigated whether positron emission tomography (PET) imaging with [18F]fludarabine ([18F]FDB) can help to differentiate central nervous system lymphoma (CNSL) from glioblastoma (GBM), which is a crucial issue in the diagnosis and manage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d649908e75c28a7f84571600d83d6eec
https://hal.science/hal-02006576

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Delivering FLT to the Central Nervous System by Means of a Promising Targeting System: Synthesis, [

Autor: Fabienne, Gourand, Mihaela-Liliana, Ţînţaş, Axelle, Henry, Méziane, Ibazizène, Martine, Dhilly, Fabien, Fillesoye, Cyril, Papamicaël, Vincent, Levacher, Louisa, Barré

Publikováno v: ACS chemical neuroscience. 8(11)

The development of delivery systems to transport some specific radiotracers across the blood-brain barrier (BBB) needs to be investigated for brain imaging. [

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3965d4133ba34de494331c678c9f2767
https://pubmed.ncbi.nlm.nih.gov/28787127

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Dihydroquinoline Carbamate Derivatives as 'Bio-oxidizable' Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation

Autor: Pierre, Bohn, Fabienne, Gourand, Cyril, Papamicaël, Méziane, Ibazizène, Martine, Dhilly, Vincent, Gembus, Florent, Alix, Mihaela-Liliana, Ţînţaş, Francis, Marsais, Louisa, Barré, Vincent, Levacher

Publikováno v: ACS chemical neuroscience. 6(5)

With the aim of improving the efficiency of marketed acetylcholinesterase (AChE) inhibitors in the symptomatic treatment of Alzheimer's disease, plagued by adverse effects arising from peripheral cholinergic activation, this work reports a biological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba9f01b364cbb5ba800750165067f9d0
https://pubmed.ncbi.nlm.nih.gov/25695305

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