Výsledky vyhledávání - "Métabolisme du fer"

Hyperferritinémie dysmétabolique : évaluation de la pratique des saignées par les médecins généralistes en Ille-et-Vilaine

Autor: Gautier, Lucie

Publikováno v: Sciences du Vivant [q-bio]. 2020

Introduction: The metabolic syndrome is the most frequent cause of hyperferritinemia. Iron depletion has been for a long time the only treatment proposed for dysmetabolic hyperferritinemia (DH). Have the new recommendations changed this practice in g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2592::b566df12f4c684f2234d236d6fc1bea9
https://dumas.ccsd.cnrs.fr/dumas-03239285/file/GAUTIERLucie.pdf

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Analyses structurales et fonctionnelles de la ferroportine humaine et mécanismes moléculaires associés à l'hémochromatose de type 4

Autor: Le Tertre, Marlène

Hemochromatosis type 4 (HC4) is considered as one of the most common forms of inherited iron overload after hemochromatosis type 1. It is associated with heterozygous mutations in the SLC40A1 gene which encodes the sole iron exporter in mammals: ferr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______166::575a416c167c8aa4385624da3a8fa9fa
https://theses.hal.science/tel-03934657

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Surcharges en fer génétiques : atypies de l'acéruloplasminémie héréditaire

Autor: O. Loréal

Publikováno v: Bulletin de l'Académie Nationale de Médecine
Bulletin de l'Académie Nationale de Médecine, Elsevier Masson, 2019, 203 (6), pp.432-439. ⟨10.1016/j.banm.2019.05.013⟩
Bulletin de l'Académie Nationale de Médecine, 2019, 203 (6), pp.432-439. ⟨10.1016/j.banm.2019.05.013⟩

The knowledge in iron metabolism obtained in the last 20 years has made it possible to draw up an understandable picture of the systemic metabolism of iron. This is mainly due to the identification of proteins playing a major role in the systemic dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82db413556a0153e1a55d6dec7a6b582
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02310283/document

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Surcharges en fer génétiques : atypies de l'acéruloplasminémie héréditaire

Autor: Loréal, Olivier

National audience; The knowledge in iron metabolism obtained in the last 20 years has made it possible to draw up an understandable picture of the systemic metabolism of iron. This is mainly due to the identification of proteins playing a major role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bf394c7f2e84bec40157538f5400979f
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02310283/document

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Dietary iron intake and breast cancer risk: modulation by an antioxidant supplementation

Autor: Fabrice Pierre, Paule Latino-Martel, Serge Hercberg, Valentin Partula, Abou Diallo, Mathilde Touvier, Bernard Srour, Pilar Galan, Philippine Fassier, Mélanie Deschasaux, Françoise Guéraud

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2016, 7 (48), pp.78994-79002. ⟨10.18632/oncotarget.12592⟩
Oncotarget, Impact journals, 2016, 7 (48), pp.78994-79002. 〈10.18632/oncotarget.12592〉
Oncotarget, 2016, 7 (48), pp.78994-79002. ⟨10.18632/oncotarget.12592⟩
Oncotarget 48 (7), 78994-79002. (2016)

Experimental results suggested that iron-induced lipid peroxidation may explain the direct associations observed between red/processed meat intakes and colorectal and breast cancer risk. However, epidemiological evidence is lacking. Thus, we investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0fbd502d146eb789b3ade3808464fd
http://europepmc.org/articles/PMC5346694

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Iron gene expression profile in atherogenic Mox macrophages

Autor: Liliana Marques, François Canonne-Hergaux, Anne Nègre-Salvayre, Luciana Costa

Publikováno v: Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2016, 1862 (6), pp.1137-1146. ⟨10.1016/j.bbadis.2016.03.004⟩
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 2016, 1862 (6), pp.1137-1146. ⟨10.1016/j.bbadis.2016.03.004⟩

Rationale The role of macrophage iron in the physiopathology of atherosclerosis is an open question that needs to be clarified. In atherosclerotic lesions, recruited macrophages are submitted to cytokines and oxidized lipids which influence their phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f57003aff52ca89b17bd686af1a0465
https://doi.org/10.1016/j.bbadis.2016.03.004

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Deciphering the molecular basis of ferroportin resistance to hepcidin: Structure/function analysis of rare SLC40A1 missense mutations found in suspected hemochromatosis type 4 patients

Autor: M. Le Tertre, Chandran Ka, Isabelle Gourlaouen, Isabelle Callebaut, Claude Férec, J. Guellec, G. Le Gac

Publikováno v: Transfusion Clinique et Biologique
Transfusion Clinique et Biologique, 2017, 24 (4), ⟨10.1016/j.tracli.2017.07.002⟩
Transfusion Clinique et Biologique, Elsevier, 2017, 24 (4), ⟨10.1016/j.tracli.2017.07.002⟩

International audience; Genetic medicine applied to the study of hemochromatosis has identified the systemic loop controlling iron homeostasis, centered on hepcidin-ferroportin interaction. Current challenges are to dissect the molecular pathways und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34612f3cb6ef03f4ff239c6423b4fd1
https://pubmed.ncbi.nlm.nih.gov/28826751

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An essential role for the bmp-smad pathway in hepcidin induction during ER stress and NAFLD/NASH

Autor: Belot, Audrey, Gourbeyre, Ophélie, Rubio, Aude, Besson-Fournier, Celine, Latour, Chloé, Gallitz, Inka, Montagner, Alexandra, Polizzi, Arnaud, Régnier, Marion, Steinbicker, Andrea U., Guillou, Hervé, Roth, Marie-Paule, Coppin, Hélène, Meynard, Delphine

Publikováno v: 7. Congress of the International Biolron Society (IBIS)
7. Congress of the International Biolron Society (IBIS), May 2017, Los Angeles, United States. 92 (8), pp.E203, 2017, American Journal of Hematology
8 (92), 2017; 7. Congress of the International Biolron Society (IBIS), Los Angeles, USA, 2017-05-07-2017-05-11, 76
7. Congress of the International Biolron Society (IBIS), May 2017, Los Angeles, United States. American Journal of Hematology, 92 (8), pp.E203, 2017, American Journal of Hematology

An essential role for the bmp-smad pathway in hepcidin induction during ER stress and NAFLD/NASH. 7. Congress of the International Biolron Society (IBIS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2a1c1e33dcfdac63f6225e96ab270ca1
https://hal.archives-ouvertes.fr/hal-01608152

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Évaluation du bilan martial à la découverte du diabète de type 1

Autor: Foloppe, Caroline

Publikováno v: Médecine humaine et pathologie. 2016

Il existe des liens entre le métabolisme du fer et le métabolisme glucidique. Ils ont été décrit initialement dans l'hémochromatose puis dans les pathologies avec surcharge en fer telles que la béta thalassémie, et dans le diabète de type 2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2592::ca35cfd5c67acad9328b0ca4f0867056
https://dumas.ccsd.cnrs.fr/dumas-01383098/file/FOLOPPE_CAROLINE.pdf

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Structural and Spectroscopic Insights into BolA-Glutaredoxin Complexes

Autor: Bo Zhang, Michael K. Johnson, Thomas Roret, Claude Didierjean, Pascale Tsan, Jérémy Couturier, Nicolas Rouhier

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (35), pp.24588-24598. ⟨10.1074/jbc.M114.572701⟩
Journal of Biological Chemistry 35 (289), 24588-24598. (2014)

International audience; Background: BolA and glutaredoxin interact together in the iron metabolism. Results: They form two types of heterodimers with different binding surfaces depending on the presence or absence of an iron-sulfur cluster. Conclusio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703b3e6325ff87aa7568badab7859891
https://hal.univ-lorraine.fr/hal-01521194

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