Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance

Autor: Laura Thirouard, Hélène Holota, Mélusine Monrose, Manon Garcia, Angélique de Haze, Christelle Damon‐Soubeyrand, Yoan Renaud, Jean‐Paul Saru, Alessia Perino, Kristina Schoonjans, Claude Beaudoin, David H. Volle

Publikováno v: Advanced Science, Vol 9, Iss 17, Pp n/a-n/a (2022)

Abstract Spermatogonial stem cells regenerate and maintain spermatogenesis throughout life, making testis a good model for studying stem cell biology. The effects of chemotherapy on fertility have been well‐documented previously. This study investi

Externí odkaz: https://doaj.org/article/1c16e21b6be44b36869d7bc07bd1b3b5

Metallome deregulation and health-related impacts due to long-term exposure to recent volcanic ash deposits: New chemical and isotopic insights

Autor: Lucie Sauzéat, Julia Eychenne, Lucia Gurioli, Maud Boyet, David E. Jessop, Roberto Moretti, Mélusine Monrose, Hélène Holota, Claude Beaudoin, David H. Volle

Publikováno v: Science of the Total Environment
Science of the Total Environment, In press, 829, pp.154383. ⟨10.1016/j.scitotenv.2022.154383⟩

International audience; Volcanic ash exposure can lead to significant health risks. Damage to the respiratory and pulmonary systems are the most evident toxic side effects although the causes of these symptoms remain unclear. Conversely, the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a82fd4bda01f7262f6729766246506
https://hal.uca.fr/hal-03610668

Metallome Deregulation and Health-Related Impacts Due to Long-Term Volcanic Ash Exposure: New Chemical and Isotopic Insights from La Soufrière De Guadeloupe Volcano

Autor: Lucie Sauzeat, Julia Eychenne, Lucia Gurioli, Maud Boyet, David E. Jessop, Roberto Moretti, Mélusine Monrose, Hélène Holota, Claude Beaudoin, David Volle

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fffebe240e34d3b2ef6adc585f76db4a
https://doi.org/10.2139/ssrn.3982115

Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases

Autor: Hélène Holota, David H. Volle, Claude Beaudoin, Françoise Caira, Manon Garcia, Mélusine Monrose, Lauriane Sèdes, Laura Thirouard

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2018, 19 (11), ⟨10.3390/ijms19113630⟩
International Journal of Molecular Sciences, MDPI, 2018, 19 (11), ⟨10.3390/ijms19113630⟩
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3630 (2018)

International audience; Structural and functional studies have provided numerous insights over the past years on how members of the nuclear hormone receptor superfamily tightly regulate the expression of drug-metabolizing enzymes and transporters. Be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a628d3a4a44f9860acec39e28dec710c
https://hal.science/hal-01930028/document

Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance.

Autor: Thirouard, Laura¹ (AUTHOR), Holota, Hélène¹ (AUTHOR), Monrose, Mélusine¹ (AUTHOR), Garcia, Manon¹ (AUTHOR), de Haze, Angélique¹ (AUTHOR), Damon‐Soubeyrand, Christelle¹ (AUTHOR), Renaud, Yoan² (AUTHOR), Saru, Jean‐Paul¹ (AUTHOR), Perino, Alessia³ (AUTHOR), Schoonjans, Kristina³ (AUTHOR), Beaudoin, Claude¹ (AUTHOR), Volle, David H.¹ (AUTHOR) david.volle@inserm.fr

Publikováno v: Advanced Science. 6/13/2022, Vol. 9 Issue 17, p1-23. 23p.