Výsledky vyhledávání - "Mélanie Sanchez"

Akademický článek

How has research on the effectiveness and safety of COVID-19 vaccination been evaluated: a scope review with emphasis on CoronaVac

Autor: Juan C. Alzate-Ángel, Paula A. Avilés-Vergara, David Arango-Londoño, Alberto Concha-Eastman, Anthony Garcés-Hurtado, Liliana López-Carvajal, Ingrid L. Minotta, Delia Ortega-Lenis, Geraldine Quintero, Sebastián Reina-Bolaños, Carlos A. Reina-Bolaños, Pablo Roa, Melanie Sánchez-Orozco, Catalina Tovar-Acero, María P. Arbeláez-Montoya

Publikováno v: Frontiers in Public Health, Vol 12 (2024)

IntroductionThe control of the COVID-19 epidemic has been focused on the development of vaccines against SARS-CoV-2. All developed vaccines have reported safety and efficacy results in preventing infection and its consequences, although the quality o

Externí odkaz: https://doaj.org/article/e067b1b1ffc34616a1463695d0b11545

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Novel Noncompetitive IL-1 Receptor–Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth

Autor: Sylvie Girard, William D. Lubell, Mathieu Nadeau-Vallée, Mélanie Sanchez, Xin Ni, Ankush Madaan, Atefeh Erfani, Xin Hou, Sarah A. Robertson, François Duhamel, Julia Palacios, Tang Zhu, Sylvain Chemtob, Baraa Noueihed, Amarilys Boudreault, David M. Olson, José Carlos Rivera, Christiane Quiniou, Kelycia B Leimert

Publikováno v: The Journal of Immunology. 195:3402-3415

Preterm birth (PTB) is firmly linked to inflammation regardless of the presence of infection. Proinflammatory cytokines, including IL-1β, are produced in gestational tissues and can locally upregulate uterine activation proteins. Premature activatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201feddf5bc5428d5695a4a46d030c1c
https://doi.org/10.4049/jimmunol.1500758

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Identification of Estrogen Receptor β as a SUMO-1 Target Reveals a Novel Phosphorylated Sumoylation Motif and Regulation by Glycogen Synthase Kinase 3β

Autor: André Tremblay, Véronique Caron, Nathalie Picard, Xavier H. Mascle, Stéphanie Bilodeau, Muriel Aubry, Mélanie Sanchez

Publikováno v: Molecular and Cellular Biology. 32:2709-2721

SUMO conjugation has emerged as a dynamic process in regulating protein function. Here we identify estrogen receptor β (ERβ) to be a new target of SUMO-1. ERβ SUMO-1 modification occurs on a unique nonconsensus sumoylation motif which becomes full

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d037bb178ff5048708dd77e4df849d7
https://doi.org/10.1128/mcb.06624-11

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Positive Feedback Activation of Estrogen Receptors by the CXCL12-CXCR4 Pathway

Autor: Nikolaus Heveker, André Tremblay, Mélanie Sanchez, Karine Sauvé, Julie Lepage

Publikováno v: Cancer Research. 69:5793-5800

Induction of estrogen-regulated gene transcription by estrogen receptors ERα and ERβ plays an important role in breast cancer development and growth. High expression of the chemokine receptor CXCR4 and its ligand CXCL12/stromal cell-derived factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857a9c46860d7e1d6e101a15ea97037e
https://doi.org/10.1158/0008-5472.can-08-4924

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Phosphorylation of Activation Function-1 Regulates Proteasome-Dependent Nuclear Mobility and E6-Associated Protein Ubiquitin Ligase Recruitment to the Estrogen Receptor β

Autor: Anne Licznar, André Tremblay, Catherine Charbonneau, Nathalie Picard, Muriel Busson, Gwendal Lazennec, Mélanie Sanchez

Publikováno v: Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2008, 22 (2), pp.317-30. ⟨10.1210/me.2007-0281⟩

International audience; The ubiquitin-proteasome pathway has been recognized as an important regulator in the hormonal response by estrogen receptor (ER) alpha, but its impact on ERbeta function is poorly characterized. In the current study, we inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb54f79c332f681c6985226a8736335e
https://doi.org/10.1210/me.2007-0281

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The Hormonal Response of Estrogen Receptor β Is Decreased by the Phosphatidylinositol 3-Kinase/Akt Pathway via a Phosphorylation-dependent Release of CREB-binding Protein

Autor: André Tremblay, Mélanie Sanchez, Karine Sauvé, Nathalie Picard

Publikováno v: Journal of Biological Chemistry. 282:4830-4840

The hormonal response of estrogen receptors (ER) alpha and ERbeta is controlled by a number of cofactors, including the general transcriptional coactivator CREB-binding protein (CBP). Growing evidence suggests that specific kinase signaling events al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d6dffda18b36b40c58cf4791e392b7
https://doi.org/10.1074/jbc.m607908200

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Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response

Autor: Jamila Ennaciri, Frank Cloutier, Mélanie Sanchez, Claudine Beauchamp, Stephen W. Michnick, Gaëlle Chognard, Atefeh Erfani, Xin Hou, Sylvie Lesage, Christiane Quiniou, José Carlos Rivera, John D. Rioux, Vijay K. Kuchroo, Sylvain Chemtob, María de la Cruz Domínguez-Punaro, Marie Vilquin, Durgajini Sivanesan, Guy Charron

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology. 307(10)

IL-23 is part of the IL-12 family of cytokines and is composed of the p19 subunit specific to IL-23 and the p40 subunit shared with IL-12. IL-23 specifically contributes to the inflammatory process of multiple chronic inflammatory autoimmune disorder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67aa68b96e7dac8b632d34053988e6e
https://pubmed.ncbi.nlm.nih.gov/25354400

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Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis

Publikováno v: Nature Medicine
Nature Medicine, Nature Publishing Group, 2014, 20 (10), pp.1165-1173. ⟨10.1038/nm.3669⟩

International audience; Neurons have an important role in retinal vascular development. Here we show that the G protein-coupled receptor (GPCR) coagulation factor II receptor-like 1 (F2rl1, previously known as Par2) is abundant in retinal ganglion ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd265a1c269d21bd9af11851a4f1f4f7
https://www.hal.inserm.fr/inserm-02983633

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Nuclear localization of platelet-activating factor receptor controls retinal neovascularization

Autor: Mélanie Sanchez, Alfredo Ribeiro-da-Silva, José Carlos Rivera, Raphael Rouget, David Hamel, Tang Zhu, Isabelle Lahaie, Tianwei Ellen Zhou, Xin Hou, Sylvain Chemtob, Vikrant K. Bhosle, Areej Al Rabea, Samy Omri

Publikováno v: Cell Discovery

Platelet-activating factor (PAF) is a pleiotropic phospholipid with proinflammatory, procoagulant and angiogenic actions on the vasculature. We and others have reported the presence of PAF receptor (Ptafr) at intracellular sites such as the nucleus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af90c64942f609f6d3d13b8d4d44cc8d
http://europepmc.org/articles/PMC4941644

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