Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mélanie Rouillier"'
Autor:
Steven P. Maher, Amélie Vantaux, Victor Chaumeau, Adeline C. Y. Chua, Caitlin A. Cooper, Chiara Andolina, Julie Péneau, Mélanie Rouillier, Zaira Rizopoulos, Sivchheng Phal, Eakpor Piv, Chantrea Vong, Sreyvouch Phen, Chansophea Chhin, Baura Tat, Sivkeng Ouk, Bros Doeurk, Saorin Kim, Sangrawee Suriyakan, Praphan Kittiphanakun, Nana Akua Awuku, Amy J. Conway, Rays H. Y. Jiang, Bruce Russell, Pablo Bifani, Brice Campo, François Nosten, Benoît Witkowski, Dennis E. Kyle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several com
Externí odkaz:
https://doaj.org/article/82bd81cce09f483dac02985c053a9b50
Autor:
Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H. I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H. Y. Jiang, Dennis E. Kyle, John H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Currently available platforms to study liver stage of Plasmodium species have limitations. Here, the authors show that primary human hepatocyte cultures in 384-well format support hypnozoite and other liver stage development and are suitable for drug
Externí odkaz:
https://doaj.org/article/0b14f6d533014ef091394f171d42ba23
Autor:
Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H. I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H. Y. Jiang, Dennis E. Kyle, John H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of Richard Thomson-Luque, which was incorrectly given as Richard Thomson Luque. This error has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/73adfbdede8e4de38681a2951dacd5ea
Autor:
Adeline C. Y. Chua, Saorin Kim, Bruce Russell, Eakpor Piv, Sivkeng Ouk, Rays H. Y. Jiang, Zaira Rizopoulos, Dennis E. Kyle, Sivchheng Phal, Pablo Bifani, Bros Doeurk, Amélie Vantaux, Julie Péneau, Nana Akua Awuku, Sangrawee Suriyakan, Brice Campo, Benoit Witkowski, Chansophea Chhin, Mélanie Rouillier, Sreyvouch Phen, Chantrea Vong, Praphan Kittiphanakun, Steven P. Maher, François Nosten, Chiara Andolina, Amy J. Conway, Caitlin A. Cooper, Baura Tat, Victor Chaumeau
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.19905. ⟨10.1038/s41598-021-99152-9⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.19905. ⟨10.1038/s41598-021-99152-9⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several compound lib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d351b9c26631b1545f18c69ca7cb66
https://hal-pasteur.archives-ouvertes.fr/pasteur-03491954/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03491954/document
Autor:
Mohammed H Cherkaoui-Rbati, Roland A. Cooper, Nina F. Gnädig, Iñigo Angulo-Barturen, Tomas Yeo, Sridevi Bashyam, Rintis Noviyanti, James M. Murithi, Gilles Courtemanche, Philip J. Rosenthal, María Belén Jiménez-Díaz, Laurent Sallé, Cécile Pascal, Rita Merino, Gilles Tuffal, Jutta Marfurt, Sergio Wittlin, Shivendra Singh, Marie José Cabanis, Lidiya Bebrevska, Jean Michel Augereau, Laura M. Sanz, Jean Michel Guillon, Sachel Mok, Paul Desert, Kelly Rubiano, Alain Pellet, Jacquin C. Niles, Guillaume Louit, Anne-Catrin Uhlemann, Nadir Bessila, Thierry Vermat, Simon Campbell, Didier Leroy, Tanguy Bozec, Jérôme Menegotto, Michel Doubovetzky, Xavier Boulenc, Benjamin Blasco, Nathalie Gobeau, Francisco-Javier Gamo, Sylvie Klieber, Elie Giraud, Jayan Joseph, Charisse Flerida A. Pasaje, Delphine Baud, Laurent Fraisse, Fanny Escudié, Jade Bath, Marie Françoise Nicolas, Mélanie Rouillier, David A. Fidock, Grennady Wirjanata, Ric N. Price, Patrick K Tumwebaze
The emergence and spread of Plasmodium falciparum resistance to first-line antimalarials creates an imperative to identify and develop potent preclinical candidates with distinct modes of action. Here, we report the identification of MMV688533, an ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c2e27d8190f65306f8587a21d03126
https://ora.ox.ac.uk/objects/uuid:39d2c646-efac-4c3d-bdef-8cf1ff7f497f
https://ora.ox.ac.uk/objects/uuid:39d2c646-efac-4c3d-bdef-8cf1ff7f497f
Autor:
James M, Murithi, Cécile, Pascal, Jade, Bath, Xavier, Boulenc, Nina F, Gnädig, Charisse Flerida A, Pasaje, Kelly, Rubiano, Tomas, Yeo, Sachel, Mok, Sylvie, Klieber, Paul, Desert, María Belén, Jiménez-Díaz, Jutta, Marfurt, Mélanie, Rouillier, Mohammed H, Cherkaoui-Rbati, Nathalie, Gobeau, Sergio, Wittlin, Anne-Catrin, Uhlemann, Ric N, Price, Grennady, Wirjanata, Rintis, Noviyanti, Patrick, Tumwebaze, Roland A, Cooper, Philip J, Rosenthal, Laura M, Sanz, Francisco Javier, Gamo, Jayan, Joseph, Shivendra, Singh, Sridevi, Bashyam, Jean Michel, Augereau, Elie, Giraud, Tanguy, Bozec, Thierry, Vermat, Gilles, Tuffal, Jean-Michel, Guillon, Jérôme, Menegotto, Laurent, Sallé, Guillaume, Louit, Marie-José, Cabanis, Marie Françoise, Nicolas, Michel, Doubovetzky, Rita, Merino, Nadir, Bessila, Iñigo, Angulo-Barturen, Delphine, Baud, Lidiya, Bebrevska, Fanny, Escudié, Jacquin C, Niles, Benjamin, Blasco, Simon, Campbell, Gilles, Courtemanche, Laurent, Fraisse, Alain, Pellet, David A, Fidock, Didier, Leroy
Publikováno v:
Sci Transl Med
The emergence and spread of Plasmodium falciparum resistance to first-line antimalarials creates an imperative to identify and develop potent preclinical candidates with distinct modes of action. Here, we report the identification of MMV688533, an ac
Autor:
Mikhail Kalinichev, Robert Johannes Lütjens, Isabelle Royer-Urios, Sonia Poli, Eric Riguet, Vincent Mutel, Francoise Girard, Mélanie Rouillier, Hasnaà Haddouk
Publikováno v:
Neuropharmacology. 114:34-47
Positive allosteric modulation of the GABAB receptor is a promising alternative to direct activation of the receptor as a therapeutic approach for treatment of addiction, chronic pain, anxiety, epilepsy, autism, Fragile X syndrome, and psychosis. Her
Autor:
Case W. McNamara, Dyann F. Wirth, Francisco-Javier Gamo, Dionicio Siegel, Yevgeniya Antonova-Koch, Dennis E. Kyle, Korina Eribez, Cullin McLean Taggard, Maureen Ibanez, François Nosten, Yang Zhong, Sabine Ottilie, Edward Owen, Victor Chaumeau, Jeremy N. Burrows, Kaisheng Chen, Elizabeth A. Winzeler, Mélanie Rouillier, Madeline R. Luth, Christie Lincoln, Stephan Meister, Juan Carlos Jado, Tomoyo Sakata-Kato, David A. Fidock, Yingyao Zhou, Kerstin Gagaring, Manuel Llinás, Jaeson Calla, Biniam Ambachew, Matthew Abraham, Amanda K. Lukens, Amy J. Conway, Fernando Neria Serrano, Manu Vanaerschot, Andrea L. Cheung, Brice Campo, Steven P. Maher, David Plouffe
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Science (New York, N.Y.), vol 362, iss 6419
Science (New York, N.y.)
Consejería de Sanidad de la Comunidad de Madrid
Science (New York, N.Y.), vol 362, iss 6419
Science (New York, N.y.)
To discover leads for next-generation chemoprotective antimalarial drugs,we tested more than 500,000 compounds for their ability to inhibit liver-stage development of luciferase-expressing Plasmodium spp. parasites (681 compounds showed a half-maxima
Autor:
François Nosten, Amy J. Conway, Samantha J. Barnes, Chiara Andolina, Steven P. Maher, Richard Thomson-Luque, Naresh Singh, Alison Roth, Silas A. Davidson, David E. Lanar, Brice Campo, Swamy R. Adapa, Benoît. Witkowski, Victor Chaumeau, Ratawan Ubalee, Stefan H. I. Kappe, Mélanie Rouillier, Amélie Vantaux, Stephen A. Kaba, Sebastian A. Mikolajczak, John H. Adams, Rays H. Y. Jiang, Dennis E. Kyle, Malina A. Bakowski, Case W. McNamara, Noah Sather, Caitlin A. Cooper
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1837. ⟨10.1038/s41467-018-04221-9⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1837. ⟨10.1038/s41467-018-04221-9⟩
Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P. falciparum lack the efficiency necessary f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ad925cee9202e5337487d4ac4c25f3
https://ora.ox.ac.uk/objects/uuid:fea5cdfe-ecad-4f45-95b9-1b6301e4fef7
https://ora.ox.ac.uk/objects/uuid:fea5cdfe-ecad-4f45-95b9-1b6301e4fef7
Autor:
Yaw Aniweh, Alamissa Soulama, Jersley Chirawurah, Felix Ansah, Harry A. Danwonno, Fanta Sogore, Melanie Rouillier, Brice Campo, Lucas Amenga-Etego, Abdoulaye A. Djimde, Gordon A. Awandare, Laurent Dembele
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Malaria treatments resulted in the decline of the deadliest Plasmodium falciparum globally while species, such as P. ovale, infections have been increasingly detected across sub-Saharan Africa. Currently, no experimental drug sensitivity dat
Externí odkaz:
https://doaj.org/article/6ea99fb2cbd348e098252355a1dc3c1f