Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mélanie Bernard-Cacciarella"'
Autor:
Julie Delyon, Selma Becherirat, Anissa Roger, Mélanie Bernard-Cacciarella, Coralie Reger De Moura, Baptiste Louveau, Samia Mourah, Céleste Lebbé, Nicolas Dumaz
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Phosphodiesterase type 4D (PDE4D) breaks down cyclic AMP (cAMP) reducing the signaling of this intracellular second messenger which plays a major role in melanocyte pathophysiology. In advanced melanoma, expression of PDE4D is inc
Externí odkaz:
https://doaj.org/article/ef174f1fd44440aebb9c049279a2a197
Autor:
Julie Delyon, Anaïs Vallet, Mélanie Bernard-Cacciarella, Isabelle Kuzniak, Coralie Reger de Moura, Baptiste Louveau, Fanélie Jouenne, Samia Mourah, Céleste Lebbé, Nicolas Dumaz
Publikováno v:
Cancers; Volume 15; Issue 11; Pages: 2888
Because BRAF-mutated melanomas are addicted to the Mitogen Activated Protein Kinase (MAPK) pathway they show a high response rate to BRAF and MEK inhibitors. However, the clinical responses to these inhibitors are often short-lived with the rapid ons