Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mélanie Beaumont"'
Autor:
Carlotta Trigila, Marc-Antoine Verdier, Laurent Pinot, Francoise Bouvet, Tiffany Mélanie Beaumont, David Broggio, Aurelie Desbree, Laurent Menard
Publikováno v:
Physics in Medicine & Biology.
Objective. Molecular radiotherapy is the most used treatment modality against malign and benign diseases of thyroid. In that context, the large heterogeneity of therapeutic doses in patients and the range of effects observed show that individualized
Autor:
Catherine Paradis-Bleau, François Sanschagrin, Normand Voyer, Roger C. Levesque, Mélanie Beaumont
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:1330-1340
As a model system for designing new inhibitors of bacterial cell division, we studied the essential and highly conserved FtsZ GTPase from Pseudomonas aeruginosa. A collection of GTP analogues were prepared using the solid-phase parallel synthesis app
Autor:
Lydia Boudreault, Mélanie Beaumont, Catherine Paradis-Bleau, Timothy D. H. Bugg, François Sanschagrin, Roger C. Levesque, Adrian J. Lloyd
Publikováno v:
Peptides. 27:1693-1700
The purified Pseudomonas aeruginosa cell wall biosynthesis MurD amide ligase enzyme was used to screen C-7-C and 12 mers peptides from phage display libraries using competitive biopanning approaches with the specific substrates D-glutamate and ATP. F
Autor:
Mélanie Beaumont, Normand Voyer, Roger C. Levesque, Ahmed El Zoeiby, François Sanschagrin, Eric Dubuc
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:1583-1592
We have developed a screening assay by thin-layer chromatography (TLC) to identify inhibitors for the bacterial essential enzymes MurA, -B, and -C. Libraries of compounds were synthesized using the mix-and-split combinatorial chemistry approach. Scre
Publikováno v:
Journal of Supramolecular Chemistry. 1:1-5
The conformation of crown ether modified peptides induced by the complexation of Z-Phe-OH and Z-Ala-OH cesium salts allows the formation of distinct chiral complexes. Both enantiomers of these protected amino acids can be distinguished by 1H NMR and