Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Mélanie, Bonhivers"'
Autor:
Denis Dacheux, Guillaume Martinez, Christine E Broster Reix, Julie Beurois, Patrick Lores, Magamba Tounkara, Jean-William Dupuy, Derrick Roy Robinson, Corinne Loeuillet, Emeline Lambert, Zeina Wehbe, Jessica Escoffier, Amir Amiri-Yekta, Abbas Daneshipour, Seyedeh-Hanieh Hosseini, Raoudha Zouari, Selima Fourati Ben Mustapha, Lazhar Halouani, Xiaohui Jiang, Ying Shen, Chunyu Liu, Nicolas Thierry-Mieg, Amandine Septier, Marie Bidart, Véronique Satre, Caroline Cazin, Zine Eddine Kherraf, Christophe Arnoult, Pierre F Ray, Aminata Toure, Mélanie Bonhivers, Charles Coutton
Publikováno v:
eLife, Vol 12 (2023)
Male infertility is common and complex, presenting a wide range of heterogeneous phenotypes. Although about 50% of cases are estimated to have a genetic component, the underlying cause often remains undetermined. Here, from whole-exome sequencing on
Externí odkaz:
https://doaj.org/article/2b37a6175cab4e93a36110639ca35769
Autor:
Christine E. Broster Reix, Miharisoa Rijatiana Ramanantsalama, Carmelo Di Primo, Laëtitia Minder, Mélanie Bonhivers, Denis Dacheux, Derrick R. Robinson
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Trypanosoma brucei belongs to a genus of protists that cause life-threatening and economically important diseases of human and animal populations in Sub-Saharan Africa. T. brucei cells are covered in surface glycoproteins, some of which are
Externí odkaz:
https://doaj.org/article/3483f07dcfb4435c85695897cfdd9cf6
Autor:
Charlotte Isch, Paul Majneri, Nicolas Landrein, Yulia Pivovarova, Johannes Lesigang, Florian Lauruol, Derrick R Robinson, Gang Dong, Mélanie Bonhivers
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009329 (2021)
The flagellar pocket (FP) is the only endo- and exocytic organelle in most trypanosomes and, as such, is essential throughout the life cycle of the parasite. The neck of the FP is maintained enclosed around the flagellum via the flagellar pocket coll
Externí odkaz:
https://doaj.org/article/342552844d3f4eaabbb926a00273446c
Autor:
Emma Stepinac, Nicolas Landrein, Daria Skwarzyńska, Patrycja Wójcik, Johannes Lesigang, Iva Lučić, Cynthia Y. He, Mélanie Bonhivers, Derrick R. Robinson, Gang Dong
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102422- (2021)
Summary: Extended synaptotagmins (E-Syts) localize at membrane contact sites between the endoplasmic reticulum (ER) and the plasma membrane to mediate inter-membrane lipid transfer and control plasma membrane lipid homeostasis. All known E-Syts conta
Externí odkaz:
https://doaj.org/article/2cd4a1bc3662459395d9553da56a500c
Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human
Autor:
Charles Coutton, Alexandra S. Vargas, Amir Amiri-Yekta, Zine-Eddine Kherraf, Selima Fourati Ben Mustapha, Pauline Le Tanno, Clémentine Wambergue-Legrand, Thomas Karaouzène, Guillaume Martinez, Serge Crouzy, Abbas Daneshipour, Seyedeh Hanieh Hosseini, Valérie Mitchell, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Jean-François Deleuze, Anne Boland, Sylviane Hennebicq, Véronique Satre, Pierre-Simon Jouk, Nicolas Thierry-Mieg, Beatrice Conne, Denis Dacheux, Nicolas Landrein, Alain Schmitt, Laurence Stouvenel, Patrick Lorès, Elma El Khouri, Serge P. Bottari, Julien Fauré, Jean-Philippe Wolf, Karin Pernet-Gallay, Jessica Escoffier, Hamid Gourabi, Derrick R. Robinson, Serge Nef, Emmanuel Dulioust, Raoudha Zouari, Mélanie Bonhivers, Aminata Touré, Christophe Arnoult, Pierre F. Ray
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Asthenozoospermia is a major cause of male infertility, and multiple morphological abnormalities of the flagella (MMAF) is a particularly severe form. Here, using whole-exome sequencing of 78 MMAF patients, the authors identify mutations in two WDR p
Externí odkaz:
https://doaj.org/article/03b883f351d94cb6999191bf43221e62
Autor:
Christine E. Broster Reix, Célia Florimond, Anne Cayrel, Amélie Mailhé, Corentin Agnero-Rigot, Nicolas Landrein, Denis Dacheux, Katharina Havlicek, Mélanie Bonhivers, Brooke Morriswood, Derrick R. Robinson
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2334 (2021)
Background: In most trypanosomes, endo and exocytosis only occur at a unique organelle called the flagellar pocket (FP) and the flagellum exits the cell via the FP. Investigations of essential cytoskeleton-associated structures located at this site h
Externí odkaz:
https://doaj.org/article/af2f51dfb5f1471ba8c85b0ce0261886
Autor:
Anna Albisetti, Célia Florimond, Nicolas Landrein, Keni Vidilaseris, Marie Eggenspieler, Johannes Lesigang, Gang Dong, Derrick Roy Robinson, Mélanie Bonhivers
Publikováno v:
PLoS Pathogens, Vol 13, Iss 11, p e1006710 (2017)
Trypanosoma brucei belongs to a group of unicellular, flagellated parasites that are responsible for human African trypanosomiasis. An essential aspect of parasite pathogenicity is cytoskeleton remodelling, which occurs during the life cycle of the p
Externí odkaz:
https://doaj.org/article/1c883b8988a746d1884e7028529545a9
Autor:
Frédéric-Antoine Dauchy, Mélanie Bonhivers, Nicolas Landrein, Denis Dacheux, Pierrette Courtois, Florian Lauruol, Sylvie Daulouède, Philippe Vincendeau, Derrick R Robinson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 11, p e0005125 (2016)
Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited alternatives and treatment toxicities, new therapeutic options are urgently needed for patients with
Externí odkaz:
https://doaj.org/article/c564165f001f4ff99abd25b8d8220950
Autor:
Miharisoa Rijatiana Ramanantsalama, Nicolas Landrein, Elina Casas, Bénédicte Salin, Corinne Blancard, Mélanie Bonhivers, Derrick R. Robinson, Denis Dacheux
Publikováno v:
Journal of cell science. 135(11)
In Trypanosoma brucei, transition fibres (TFs) form a nine-bladed pattern-like structure connecting the base of the flagellum to the flagellar pocket membrane. Despite the characterization of two TF proteins, CEP164C and T. brucei (Tb)RP2, little is
Autor:
Carmelo Di Primo, Laetitia Minder, Denis Dacheux, Miharisoa Rijatiana Ramanantsalama, Derrick R. Robinson, Christine E. Broster Reix, Mélanie Bonhivers
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Microbiology Spectrum
Microbiology Spectrum, 2021, 9 (2), ⟨10.1128/Spectrum.00915-21⟩
Microbiology Spectrum
Microbiology Spectrum, 2021, 9 (2), ⟨10.1128/Spectrum.00915-21⟩
International audience; Trypanosoma brucei belongs to a genus of protists that cause life-threatening and economically important diseases of human and animal populations in Sub-Saharan Africa. T. brucei cells are covered in surface glycoproteins, som