Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Mårten Fernö"'
Autor:
Helena Fohlin, Anna Nordenskjöld, Johan Rosell, Mårten Fernö, Tommy Fornander, Lisa Rydén, Lambert Skoog, Bo Nordenskjöld, Olle Stål
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background: Hormone receptor positivity predicts benefit from endocrine therapy but the knowledge about the long-term survival of patients with different tumor receptor levels is limited. In this study, we describe the 25 years outcome of tamoxifen (
Externí odkaz:
https://doaj.org/article/70fb0a9414d446158f65dbae4436b48e
Autor:
Terese Engström, Maria Ekholm, Mårten Fernö, Christine Lundgren, Bo Nordenskjöld, Olle Stål, Pär-Ola Bendahl, Julia Tutzauer, Lisa Rydén
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
ABSTRACT Background and purpose: Tamoxifen remains an important adjuvant treatment in premenopausal patients with hormone receptor-positive breast cancer. Thus, determination of hormone receptors is important. Here, we compare cytosol-based methods,
Externí odkaz:
https://doaj.org/article/3af36158a1dc4d0f99ce91c65e6aa575
Autor:
Christine Lundgren, Julia Tutzauer, Sarah E. Church, Olle Stål, Maria Ekholm, Carina Forsare, Bo Nordenskjöld, Mårten Fernö, Pär-Ola Bendahl, Lisa Rydén
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-20 (2023)
Abstract Background Gene expression (GEX) signatures in breast cancer provide prognostic information, but little is known about their predictive value for tamoxifen treatment. We examined the tamoxifen-predictive value and prognostic effects of diffe
Externí odkaz:
https://doaj.org/article/f09fa8d43985469ab9231f4bffcde4a9
Autor:
Tommaso De Marchi, Paul Theodor Pyl, Martin Sjöström, Susanne Erika Reinsbach, Sebastian DiLorenzo, Björn Nystedt, Lena Tran, Gyula Pekar, Fredrik Wärnberg, Irma Fredriksson, Per Malmström, Mårten Fernö, Lars Malmström, Johan Malmstöm, Emma Niméus
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
A proteogenomic analysis of matching primary breast cancer and ipsilateral breast tumor recurrence (IBTR) samples provides insight into the development of IBTR and may be useful in identifying biomarkers for IBTR formation.
Externí odkaz:
https://doaj.org/article/7fcdfaaf09f349e4a6ae38eff9a3e17b
Autor:
Christine Lundgren, Pär-Ola Bendahl, Sarah E. Church, Maria Ekholm, Mårten Fernö, Carina Forsare, Ute Krüger, Bo Nordenskjöld, Olle Stål, Lisa Rydén
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract PAM50 intrinsic subtyping and risk of recurrence (ROR) score are approved for risk profiling in postmenopausal women. We aimed to examine their long-term prognostic value in terms of breast cancer-free interval (BCFi) and overall survival (O
Externí odkaz:
https://doaj.org/article/6ac42a655e1c44b8aaf372ca6538233d
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract 27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association betwee
Externí odkaz:
https://doaj.org/article/42ce64d0f0ad4806b4fab2233af6540e
Autor:
Christine Lundgren, Pär-Ola Bendahl, Maria Ekholm, Mårten Fernö, Carina Forsare, Ute Krüger, Bo Nordenskjöld, Olle Stål, Lisa Rydén
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background Tumour-infiltrating lymphocytes (TILs) are of important prognostic and predictive value in human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) and triple-negative breast cancer (TNBC), but their clinical r
Externí odkaz:
https://doaj.org/article/197a7ddeb1714ec8aafbbb51dc62b994
Autor:
Martin Sjöström, Cynthia Veenstra, Erik Holmberg, Per Karlsson, Fredrika Killander, Per Malmström, Emma Niméus, Mårten Fernö, Olle Stål
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2713-2726 (2020)
Experimental studies suggest that hepatocyte growth factor (HGF) and its transmembrane tyrosine kinase receptor, Met, in part also relying on Akt kinase activity, mediate radioresistance. We investigated the importance of these biomarkers for the ris
Externí odkaz:
https://doaj.org/article/efd64e9c664e42559b7651d5419d26bc
Autor:
Rolf Søkilde, Helena Persson, Anna Ehinger, Anna Chiara Pirona, Mårten Fernö, Cecilia Hegardt, Christer Larsson, Niklas Loman, Martin Malmberg, Lisa Rydén, Lao Saal, Åke Borg, Johan Vallon-Christerson, Carlos Rovira
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Accurate classification of breast cancer using gene expression profiles has contributed to a better understanding of the biological mechanisms behind the disease and has paved the way for better prognostication and treatment predi
Externí odkaz:
https://doaj.org/article/87fb28887c884bf19a69a6e920caeda5
Autor:
Carina Forsare, Martin Bak, Anna-Karin Falck, Dorthe Grabau, Fredrika Killander, Per Malmström, Lisa Rydén, Olle Stål, Marie Sundqvist, Pär-Ola Bendahl, Mårten Fernö
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Prognostic factors in breast cancer are often measured on a continuous scale, but categorized for clinical decision-making. The primary aim of this study was to evaluate if accounting for continuous non-linear effects of the three
Externí odkaz:
https://doaj.org/article/3166cbdac85d45b787b1987b6afb105e