Zobrazeno 1 - 10
of 8 063
pro vyhledávání: '"Märten A"'
Autor:
Marten A. Fischer, Al-Hassan M. Mustafa, Kristin Hausmann, Ramy Ashry, Anita G. Kansy, Magdalena C. Liebl, Christina Brachetti, Andrea Piée-Staffa, Matthes Zessin, Hany S. Ibrahim, Thomas G. Hofmann, Mike Schutkowski, Wolfgang Sippl, Oliver H. Krämer
Publikováno v:
Journal of Advanced Research, Vol 60, Iss , Pp 201-214 (2024)
Introduction: Posttranslational modification of proteins by reversible acetylation regulates key biological processes. Histone deacetylases (HDACs) catalyze protein deacetylation and are frequently dysregulated in tumors. This has spurred the develop
Externí odkaz:
https://doaj.org/article/0bdd50c9fd09429e928b1f2b75be1138
Autor:
Melanie Haar, Franz Felix Konen, Marten A. Gehlhaar, Irene Oluwatoba-Popoola, Emilia Donicova, Marija Wachsmann, Ahmed Lubbad, Katerina Hufendiek, Amelie Pielen, Bettina Hohberger, Christian Mardin, Stefan Gingele, Nils K. Prenzler, Diana Ernst, Torsten Witte, Carsten Framme, Thomas Skripuletz, Tabea Seeliger, Anna Bajor
Publikováno v:
Therapeutic Advances in Ophthalmology, Vol 16 (2024)
Background: Sjögren’s syndrome is an autoimmune disease characterized by sicca symptoms and various extraglandular manifestations including vasculitis. Neurological involvement occurs frequently (Neuro-Sjögren) and often mimics immune neuropathie
Externí odkaz:
https://doaj.org/article/5b53532b8dff45019cd72bca4d35264e
Autor:
Marlon J. A. de Haan, Marleen E. Jacobs, Franca M. R. Witjas, Annemarie M. A. de Graaf, Elena Sánchez-López, Sarantos Kostidis, Martin Giera, Francisco Calderon Novoa, Tunpang Chu, Markus Selzner, Mehdi Maanaoui, Dorottya K. de Vries, Jesper Kers, Ian P. J. Alwayn, Cees van Kooten, Bram Heijs, Gangqi Wang, Marten A. Engelse, Ton J. Rabelink
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The growing disparity between the demand for transplants and the available donor supply, coupled with an aging donor population and increasing prevalence of chronic diseases, highlights the urgent need for the development of platforms enabli
Externí odkaz:
https://doaj.org/article/eeb05a48024a487b97f487db593e8854
Autor:
Cody J. Dey, Erik I. Tuononen, Emma E. Hodgson, D. Andrew R. Drake, Marten A. Koops, Cindy Chu
Publikováno v:
FACETS, Vol 9, Iss , Pp 1-9 (2024)
Habitat sensitivity is a consideration for decision-making under environmental laws in many jurisdictions. However, habitat sensitivity has been variously defined and there is no consistent approach to its quantification, which limits our understandi
Externí odkaz:
https://doaj.org/article/0a07b3c04a794225b5f01d7f70e40798
Autor:
Nathalie A. Reilly, Friederike Sonnet, Koen F. Dekkers, Joanneke C. Kwekkeboom, Lucy Sinke, Stan Hilt, Hayat M. Suleiman, Marten A. Hoeksema, Hailiang Mei, Erik W. van Zwet, Bart Everts, Andreea Ioan-Facsinay, J. Wouter Jukema, Bastiaan T. Heijmans
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109496- (2024)
Summary: T cells are the most common immune cells in atherosclerotic plaques, and the function of T cells can be altered by fatty acids. Here, we show that pre-exposure of CD4+ T cells to oleic acid, an abundant fatty acid linked to cardiovascular ev
Externí odkaz:
https://doaj.org/article/5f40b85a5de4481da650e5538f4737d5
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/998cc91a33e841dab8db96c7b1ccf104
Autor:
Lorenzo Piemonti, Hanne Scholz, Dide de Jongh, Julie Kerr-Conte, Aart van Apeldoorn, James A. M. Shaw, Marten A. Engelse, Eline Bunnik, Markus Mühlemann, Karolina Pal-Kutas, William E. Scott, Jérémy Magalon, Patrick Kugelmeier, Ekaterine Berishvili
Publikováno v:
Transplant International, Vol 36 (2023)
The field of transplantation has witnessed the emergence of Advanced Therapy Medicinal Products (ATMPs) as highly promising solutions to address the challenges associated with organ and tissue transplantation. ATMPs encompass gene therapy, cell thera
Externí odkaz:
https://doaj.org/article/f85f617a2a2a4eaab2738829f02cdb81
Autor:
Suzanne A.E. van Wouw, Marlene van den Berg, Maroua El Ouraoui, Amber Meurs, Jenina Kingma, Roelof Ottenhoff, Melanie Loix, Marten A. Hoeksema, Koen Prange, Gerard Pasterkamp, Jerome J.A. Hendriks, Jeroen F.J. Bogie, Jan B. van Klinken, Frederic M. Vaz, Aldo Jongejan, Menno P.J. de Winther, Noam Zelcer
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100325- (2023)
Lysoplasmalogens are a class of vinyl ether bioactive lipids that have a central role in plasmalogen metabolism and membrane fluidity. The liver X receptor (LXR) transcription factors are important determinants of cellular lipid homeostasis owing to
Externí odkaz:
https://doaj.org/article/5be45c9062f1454c8a49dcd0a8d8b7ff
Autor:
Halima Giovanna Ahmad, Caleb Jordan, Roald van den Boogaart, Daan Waardenburg, Christos Zachariadis, Pasquale Mastrovito, Asen Lyubenov Georgiev, Domenico Montemurro, Giovanni Piero Pepe, Marten Arthers, Alessandro Bruno, Francesco Tafuri, Oleg Mukhanov, Marco Arzeo, Davide Massarotti
Publikováno v:
Condensed Matter, Vol 8, Iss 1, p 29 (2023)
The strong requirement for high-performing quantum computing led to intensive research on novel quantum platforms in the last decades. The circuital nature of Josephson-based quantum superconducting systems powerfully supports massive circuital freed
Externí odkaz:
https://doaj.org/article/dd1e89c0e0534830b1427b38b8b2b103
Autor:
Zeyang Shen, Rick Z Li, Thomas A Prohaska, Marten A Hoeksema, Nathan J Spann, Jenhan Tao, Gregory J Fonseca, Thomas Le, Lindsey K Stolze, Mashito Sakai, Casey E Romanoski, Christopher K Glass
Publikováno v:
eLife, Vol 11 (2022)
Regulation of gene expression requires the combinatorial binding of sequence-specific transcription factors (TFs) at promoters and enhancers. Prior studies showed that alterations in the spacing between TF binding sites can influence promoter and enh
Externí odkaz:
https://doaj.org/article/98d44d7ff9f64f50bf3ced74f1b45425