Zobrazeno 1 - 10
of 1 845
pro vyhledávání: '"Männistö, P."'
Autor:
Ville Männistö, Veikko Salomaa, Antti Jula, Annamari Lundqvist, Satu Männistö, Markus Perola, Fredrik Åberg
Publikováno v:
JHEP Reports, Vol 6, Iss 10, Pp 101172- (2024)
Background & Aims: A new nomenclature and subclassification for steatotic liver disease (SLD) was recently introduced. We validated the prognostic value of SLD subclasses in a Finnish population-based cohort and explored the impact of metabolic risk
Externí odkaz:
https://doaj.org/article/dafc355a199b4663bc004ebe05471199
Autor:
K. Jentzsch, E. Männistö, M. E. Marushchak, A. Korrensalo, L. van Delden, E.-S. Tuittila, C. Knoblauch, C. C. Treat
Publikováno v:
Biogeosciences, Vol 21, Pp 3761-3788 (2024)
Cold-season emissions substantially contribute to the annual methane budget of northern wetlands, yet they remain underestimated by process-based models. Models show significant uncertainty in their parameterization of processes, particularly during
Externí odkaz:
https://doaj.org/article/c024050e3efa4b4cbbf6166abfc4d8ea
Autor:
Rochelle N. Naylor, Kashyap A. Patel, Jarno L. T. Kettunen, Jonna M. E. Männistö, Julie Støy, Jacques Beltrand, Michel Polak, ADA/EASD PMDI, Tina Vilsbøll, Siri A. W. Greeley, Andrew T. Hattersley, Tiinamaija Tuomi
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-17 (2024)
Abstract Background Beta-cell monogenic forms of diabetes have strong support for precision medicine. We systematically analyzed evidence for precision treatments for GCK-related hyperglycemia, HNF1A-, HNF4A- and HNF1B-diabetes, and mitochondrial dia
Externí odkaz:
https://doaj.org/article/c6131c68651d4205b6f18e53add807da
Autor:
Johanna Matilainen, Viivi Berg, Maija Vaittinen, Ulla Impola, Anne-Mari Mustonen, Ville Männistö, Marjo Malinen, Veera Luukkonen, Natalia Rosso, Tanja Turunen, Pirjo Käkelä, Silvia Palmisano, Uma Thanigai Arasu, Sanna P. Sihvo, Niina Aaltonen, Kai Härkönen, Andrea Caddeo, Dorota Kaminska, Päivi Pajukanta, Minna U. Kaikkonen, Claudio Tiribelli, Reijo Käkelä, Saara Laitinen, Jussi Pihlajamäki, Petteri Nieminen, Kirsi Rilla
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Obesity is a worldwide epidemic characterized by adipose tissue (AT) inflammation. AT is also a source of extracellular vesicles (EVs) that have recently been implicated in disorders related to metabolic syndrome. However, our und
Externí odkaz:
https://doaj.org/article/ceb5613430cf4656a79cba7215ebe4ee
We introduce the nivel2 software for multi-level modelling. Multi-level modelling is a modelling paradigm where a model element may be simultaneously a type for and an instance of other elements under some constraints. This contrasts traditional mode
Externí odkaz:
http://arxiv.org/abs/2303.12171
Previous research has demonstrated that preparing students for life in software engineering is not a trivial task. Authentic learning experiences are challenging to provide, and there are gaps between what students have done at the university and wha
Externí odkaz:
http://arxiv.org/abs/2301.07020
Tertiary education institutions aim to prepare their computer science and software engineering students for working life. While much of the technical principles are covered in lower-level courses, team-based capstone projects are a common way to prov
Externí odkaz:
http://arxiv.org/abs/2301.03554
Publikováno v:
Cogent Education, Vol 11, Iss 1 (2024)
The increasing digitalization of working methods require new competencies from health and social care professionals. In addition, the development of person-centered digital health and social services call for interprofessional expertise and a social
Externí odkaz:
https://doaj.org/article/83266179d75840c3a4a9afc6db0be0f1
Autor:
Meri Simojoki, Satu Männistö, Heli Tapanainen, Mirkka Maukonen, Liisa M. Valsta, Suvi T. Itkonen, Anne-Maria Pajari, Niina E. Kaartinen
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/ddb6e04706ce4e90a18c290bbba19af0
Publikováno v:
Neurology and Therapy, Vol 13, Iss 4, Pp 1039-1054 (2024)
Abstract In the 1980s, Orion Pharma, then a mid-ranking Nordic area pharmaceutical company, established a drug development programme on the inhibition of catechol O-methyltransferase (COMT). This enzyme, which plays an important role in the inactivat
Externí odkaz:
https://doaj.org/article/ab03be095a6f4a37aad0b8a4273760c0