Výsledky vyhledávání - "Mäki, J. (Joni)"

Dissertation/ Thesis

Lysyl oxidases:cloning and characterization of the fourth and the fifth human lysyl oxidase isoenzymes, and the consequences of a targeted inactivation of the first described lysyl oxidase isoenzyme in mice

Autor: Mäki, J. (Joni)

Lysyl oxidases (EC 1.4.3.13, protein-lysine 6-oxidases) are extracellular copper enzymes that initiate the cross-linking of collagens and elastin by catalyzing oxidative deamination of the ε-amino group in certain lysine and hydroxylysine residues.

Externí odkaz: http://urn.fi/urn:isbn:9514267397

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Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice

Autor: Settelmeier, S. (Stephan), Schreiber, T. (Timm), Mäki, J. (Joni), Byts, N. (Nadiya), Koivunen, P. (Peppi), Myllyharju, J. (Johanna), Fandrey, J. (Joachim)

The transcription factor Hypoxia-inducible factor 1 (HIF-1) plays a pivotal role in tissue regeneration. HIF-1 is negatively controlled by O2-dependent prolyl hydroxylases with a predominant role of prolyl hydroxylase 2 isoform (Phd2). Transgenic mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2423::8888d44ad0081c8dea426132ed9b7144
http://urn.fi/urn:nbn:fi-fe2020090267238

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Hypoxia-inducible factor prolyl 4-hydroxylases regulating erythropoiesis, and hypoxia-inducible lysyl oxidase regulating skeletal muscle development during embryogenesis

Autor: Laitala, A. (Anu)

Erythropoiesis is the process of red blood cell production. The main regulator is the erythropoietin (EPO) hormone, which is strongly upregulated in low oxygen concentration (hypoxia) in cells via the hypoxia-inducible transcription factor HIF. The s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2423::b257cd15fc61bb70187b38c170726b9e
http://urn.fi/urn:isbn:9789526206943

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