Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Mário Sérgio, Mantovani"'
Autor:
Virginia Marcia Concato-Lopes, Taylon Felipe Silva, Mariana Barbosa Detoni, Ellen Mayara Souza Cruz, Manoela Daiele Gonçalves, Bruna Taciane da Silva Bortoleti, Fernanda Tomiotto-Pellissier, Amanda Cristina Machado Carloto, Maria Beatriz Madureira, Ana Carolina Jacob Rodrigues, Jéseka Gabriela Schirmann, Aneli M. Barbosa-Dekker, Robert F.H. Dekker, Ivete Conchon-Costa, Carolina Panis, Danielle Lazarin-Bidóia, Milena Menegazzo Miranda-Sapla, Mário Sérgio Mantovani, Wander R. Pavanelli
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115979- (2024)
Lung cancer is one of the leading causes of cancer-related deaths in men and women worldwide. Current treatments have limited efficacy, cause significant side effects, and cells can develop drug resistance. New therapeutic strategies are needed to di
Externí odkaz:
https://doaj.org/article/b311234cd7e94964b1d88263389f9c4a
Autor:
Gláucia Fernanda Rocha D´Epiro, Simone Cristine Semprebon, Andressa Megumi Niwa, Lilian Areal Marques, Bruna Isabela Biazi, Thalita Alves Zanetti, Ingrid Felicidade, Adrivanio Baranoski, Mário Sérgio Mantovani
Publikováno v:
Acta Scientiarum: Biological Sciences, Vol 45, Iss 1 (2023)
Chlorophyllin, a semisynthetic compound derived from chlorophyll, has been a focus in cancer prevention because it exerts important biological activities, such as antigenotoxic, antioxidative and anticarcinogenic activities. The aim of this study was
Externí odkaz:
https://doaj.org/article/dbcd81a83a0f44d4ae46c842e48f7f42
Autor:
Clisia Mara Carreira, Simone Cristine Semprebon, Daniele Sartori, Sandra Regina Lepri, Mário Sérgio Mantovani
Publikováno v:
Acta Scientiarum: Biological Sciences, Vol 44, Iss 1 (2022)
β-Glucans (βG) are polysaccharides widely distributed in nature with chemopreventive properties. The aim of this study was to investigate the effects of βG and the combined treatment with doxorubicin (Dox) on cell viability and mRNA levels of gene
Externí odkaz:
https://doaj.org/article/678b05d5c1454d5e94924caec76eae3c
Autor:
Muriel Almeida Xavier, Marcelo Tempesta de Oliveira, Adrivanio Baranoski, Mário Sérgio Mantovani
Publikováno v:
Saudi Journal of Biological Sciences, Vol 25, Iss 8, Pp 1568-1576 (2018)
There is a lack of consensus on whether the role of folate in cancer cells is protective or harmful. The use of folates in combination with cancer-targeting therapeutic regimens requires detailed information to ensure their safe and proper use. There
Externí odkaz:
https://doaj.org/article/e2ea994aa9fc47b497b726303d76fa57
Autor:
Priscila Lumi Ishii, Rodrigo Juliano Oliveira, Mariana de Oliveira Mauro, Verônica Assalin Zorgetto-Pinheiro, Daniele Sartori, Sandra Regina Lepri, Adrivanio Baranoski, Mário Sérgio Mantovani, Lúcia Regina Ribeiro
Publikováno v:
Brazilian Archives of Biology and Technology, Vol 63 (2020)
Abstract The α-tomatine is a steroidal glycoalkaloid found in immature tomatoes (Lycopersicon esculentum) that has important biological functions including the inhibition of cancer cell growth and preventing metastasis. This study aimed to evaluate
Externí odkaz:
https://doaj.org/article/41f24598501d43869480261888690d46
Autor:
Ingrid Felicidade, Daniele Sartori, Susan L.M. Coort, Simone Cristine Semprebon, Andressa Megumi Niwa, Gláucia Fernanda Rocha D’Epiro, Bruna Isabela Biazi, Lilian Areal Marques, Chris T. Evelo, Mário Sérgio Mantovani, Lúcia Regina Ribeiro
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 1, Pp 397-408 (2018)
Background/Aims: Compared with non-obese individuals, obese individuals commonly store more vitamin D in adipose tissue. VDR expression in adipose tissue can influence adipogenesis and is therefore a target pathway deserving further study. This study
Externí odkaz:
https://doaj.org/article/ec47e97e1dcd454cb0ec11184033704b
Publikováno v:
Semina: Ciências Biológicas e da Saúde, Vol 37, Iss 1, Pp 43-52 (2016)
Abstract: The ?-tomatine is a glycoalkaloid found in immature tomatoes (Lycopersicon esculetum). Currently, ?-tomatine has shown anticancer effects due to its anti-proliferative property. Stressors are one of the factors contributing to the antiproli
Externí odkaz:
https://doaj.org/article/485f6807f3a04292a0c9656b161d6aab
Autor:
Ana Luiza Sereia, Marcelo Tempesta de Oliveira, Adrivanio Baranoski, Leila Larisa Medeiros Marques, Fabianne Martins Ribeiro, Raquel Garcia Isolani, Daniela Cristina de Medeiros, Danielly Chierrito, Danielle Lazarin-Bidóia, Acácio Antonio Ferreira Zielinski, Cláudio Roberto Novello, Celso Vataru Nakamura, Mário Sérgio Mantovani, João Carlos Palazzo de Mello
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212089 (2019)
Alzheimer's disease (AD) is the most common form of dementia and has no cure. Therapeutic strategies focusing on the reduction of oxidative stress, modulation of amyloid-beta (Aβ) toxicity and inhibition of tau protein hyperphosphorylation are warra
Externí odkaz:
https://doaj.org/article/ce68471b27de437f8cd742f29a3273f0
Autor:
Leonardo Campos Zanelatto, Patrícia Benites Gonçalves da Silva, Daniele Sartori, Carolina Panis, Sandra Lepri, Ângelo de Fátima, Mário Sérgio Mantovani
Publikováno v:
Genetics and Molecular Biology, Vol 39, Iss 2, Pp 270-278 (2016)
Abstract The identification of antitumoral substances is the focus of intense biomedical research. Two structural analogues of thalidomide, LNO3 and L3, are two synthetic compounds that might possess such antitumor properties. We evaluated the toxico
Externí odkaz:
https://doaj.org/article/bf17a3a9b141488e9972848cc885174c
Autor:
Luciano Henrique Campestrini, Monique A G Silva, Mário Sérgio Mantovani, Carmen Lúcia de Oliveira Petkowicz, Simone Cristine Semprebon, Raquely M Lenzi, Selma Faria Zawadzki-Baggio, Jonas Augusto Rizzato Paschoal, Juliana Bello Baron Maurer
Publikováno v:
Nutrition and Cancer. 74:1322-1337
The consumption of glucosinolate (GL)-rich foods, including Brassica vegetables, such as mustard, broccoli, and maca, is associated with decreased risk of developing cancer. The GL content in maca, which is recognized as a "superfood", is approximate