Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mário S, Rodrigues"'
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1091 (2024)
Atomic force microscopy (AFM) imaging enables the visualization of protein molecules with high resolution, providing insights into their shape, size, and surface topography. Here, we use AFM to study the aggregation process of protein S100A9 in physi
Externí odkaz:
https://doaj.org/article/e2d72e8ed5d84489aa3e7e9fb5324ae5
Autor:
Guilherme G. Moreira, François-Xavier Cantrelle, Andrea Quezada, Filipa S. Carvalho, Joana S. Cristóvão, Urmi Sengupta, Nicha Puangmalai, Ana P. Carapeto, Mário S. Rodrigues, Isabel Cardoso, Güenter Fritz, Federico Herrera, Rakez Kayed, Isabelle Landrieu, Cláudio M. Gomes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The calcium binding protein S100B is an abundantly expressed protein in the brain and has neuro-protective functions by inhibiting Aβ aggregation and metal ion toxicity. Here, the authors combine cell biology and biochemical experiments with chemica
Externí odkaz:
https://doaj.org/article/c84f299d39b043bfadec87ae6bbc7bf3
Autor:
Ricardo A. Ribeiro, Miguel V. Vitorino, Cláudia P. Godinho, Nuno Bourbon-Melo, Tiago T. Robalo, Fábio Fernandes, Mário S. Rodrigues, Isabel Sá-Correia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract This work describes a coordinate and comprehensive view on the time course of the alterations occurring at the level of the cell wall during adaptation of a yeast cell population to sudden exposure to a sub-lethal stress induced by acetic ac
Externí odkaz:
https://doaj.org/article/620c704f2a7841198df8f19133f799ac
Autor:
Ricardo A. Ribeiro, Cláudia P. Godinho, Miguel V. Vitorino, Tiago T. Robalo, Fábio Fernandes, Mário S. Rodrigues, Isabel Sá-Correia
Publikováno v:
Journal of Fungi, Vol 8, Iss 2, p 103 (2022)
Acetic acid is a major inhibitory compound in several industrial bioprocesses, in particular in lignocellulosic yeast biorefineries. Cell envelope remodeling, involving cell wall and plasma membrane composition, structure and function, is among the m
Externí odkaz:
https://doaj.org/article/f8c14ffd785f49fb8cba370838b36cd7
Autor:
Ana P. Carapeto, Miguel V. Vitorino, João D. Santos, Sofia S. Ramalho, Tiago Robalo, Mário S. Rodrigues, Carlos M. Farinha
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2916 (2020)
Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). A single recessive mutation, the deletion of phenylalanine 508 (F508del), causes severe CF and resides on 70% of mutant c
Externí odkaz:
https://doaj.org/article/6b62412c95014885b1397de7259b34d6
Autor:
Filipe M. Sousa, Patrícia Pires, Andreia Barreto, Patrícia N. Refojo, Micael S. Silva, Pedro B. Fernandes, Ana P. Carapeto, Tiago T. Robalo, Mário S. Rodrigues, Mariana G. Pinho, Eurico J. Cabrita, Manuela M. Pereira
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1864:148948
Staphylococcus aureus is an opportunistic pathogen and one of the most frequent causes for community acquired and nosocomial bacterial infections. Even so, its energy metabolism is still under explored and its respiratory enzymes have been vastly ove
Autor:
Ricardo A. Ribeiro, Cláudia P. Godinho, Miguel V. Vitorino, Tiago T. Robalo, Fábio Fernandes, Mário S. Rodrigues, Isabel Sá-Correia
Publikováno v:
Journal of Fungi; Volume 8; Issue 2; Pages: 103
Acetic acid is a major inhibitory compound in several industrial bioprocesses, in particular in lignocellulosic yeast biorefineries. Cell envelope remodeling, involving cell wall and plasma membrane composition, structure and function, is among the m
Autor:
Joana S, Cristóvão, Guilherme G, Moreira, Filipe E P, Rodrigues, Ana P, Carapeto, Mário S, Rodrigues, Isabel, Cardoso, António E N, Ferreira, Miguel, Machuqueiro, Guenter, Fritz, Cláudio M, Gomes
Publikováno v:
Chemical communications (Cambridge, England). 57(3)
S100B is an extracellular protein implicated in Alzheimer's Disease and a suppressor of amyloid-β aggregation. Herein we report a mechanism tying Cu2+ binding to a change in assembly state yielding disulfide cross-linked oligomers with higher anti-a