Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mária, Lódi"'
Autor:
Mária Lódi, Viktor Bánhegyi, Beáta Bódi, Alexandra Gyöngyösi, Árpád Kovács, Anita Árokszállási, Nazha Hamdani, Miklós Fagyas, István Édes, Zoltán Csanádi, István Czuriga, Zoltán Kisvárday, István Lekli, Péter Bai, Attila Tóth, Zoltán Papp, Dániel Czuriga
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background Cardiomyopathy is a common side effect of doxorubicin (DOX) chemotherapy. Despite intensive research efforts in the field, there is still no evidence available for routine cardioprotective prophylaxis to prevent cardiotoxicity in
Externí odkaz:
https://doaj.org/article/2ac15617c7aa42b2999a5adb53714ca2
Autor:
Mária Lódi, Dániel Priksz, Gábor Áron Fülöp, Beáta Bódi, Alexandra Gyöngyösi, Lilla Nagy, Árpád Kovács, Attila Béla Kertész, Judit Kocsis, István Édes, Zoltán Csanádi, István Czuriga, Zoltán Kisvárday, Béla Juhász, István Lekli, Péter Bai, Attila Tóth, Zoltán Papp, Dániel Czuriga
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Chemotherapy-induced left ventricular dysfunction represents a major clinical problem, which is often only recognised at an advanced stage, when supportive therapy is ineffective. Although an early heart failure treatment could po
Externí odkaz:
https://doaj.org/article/8267468ab3be437ba254b9563f758148
Autor:
Detmar Kolijn, Árpád Kovács, Melissa Herwig, Mária Lódi, Marcel Sieme, Abdulatif Alhaj, Peter Sandner, Zoltán Papp, Peter H. Reusch, Peter Haldenwang, Ines Falcão-Pires, Wolfgang A. Linke, Kornelia Jaquet, Sophie Van Linthout, Andreas Mügge, Carsten Tschöpe, Nazha Hamdani
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
AimsOur aim was to investigate the effect of nitric oxide (NO)-independent activation of soluble guanylyl cyclase (sGC) on cardiomyocyte function in a hypertensive animal model with diastolic dysfunction and in biopsies from human heart failure with
Externí odkaz:
https://doaj.org/article/064aa569e9a9424186efba77704f94b1
Autor:
Melissa Herwig, Detmar Kolijn, Mária Lódi, Soraya Hölper, Árpád Kovács, Zoltán Papp, Kornelia Jaquet, Peter Haldenwang, Cris Dos Remedios, Peter H. Reusch, Andreas Mügge, Marcus Krüger, Jens Fielitz, Wolfgang A. Linke, Nazha Hamdani
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The giant protein titin performs structure-preserving functions in the sarcomere and is important for the passive stiffness (Fpassive) of cardiomyocytes. Protein kinase D (PKD) enzymes play crucial roles in regulating myocardial contraction, hypertro
Externí odkaz:
https://doaj.org/article/6c6cfd0482f04fd7bfbaae9b047f2698
Autor:
Melina Tangos, Heidi Budde, Detmar Kolijn, Marcel Sieme, Saltanat Zhazykbayeva, Mária Lódi, Melissa Herwig, Kamilla Gömöri, Roua Hassoun, Emma Louise Robinson, Toni Luise Meister, Kornelia Jaquet, Árpád Kovács, Julian Mustroph, Katja Evert, Nina Babel, Miklós Fagyas, Diana Lindner, Klaus Püschel, Dirk Westermann, Hans Georg Mannherz, Francesco Paneni, Stephanie Pfaender, Attila Tóth, Andreas Mügge, Samuel Sossalla, Nazha Hamdani
Publikováno v:
International Journal of Cardiology. 362:196-205
The respiratory illness triggered by severe acute respiratory syndrome virus-2 (SARS-CoV-2) is often particularly serious or fatal amongst patients with pre-existing heart conditions. Although the mechanisms underlying SARS-CoV-2-related cardiac dama
Autor:
Roua Hassoun, Heidi Budde, Hans Georg Mannherz, Mária Lódi, Setsuko Fujita-Becker, Kai Thorsten Laser, Anna Gärtner, Karin Klingel, Desirée Möhner, Robert Stehle, Innas Sultana, Thomas Schaaf, Mario Majchrzak, Verena Krause, Christian Herrmann, Marc M. Nowaczyk, Andreas Mügge, Gabriele Pfitzer, Rasmus R. Schröder, Nazha Hamdani, Hendrik Milting, Kornelia Jaquet, Diana Cimiotti
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9625 (2021)
Rare pediatric non-compaction and restrictive cardiomyopathy are usually associated with a rapid and severe disease progression. While the non-compaction phenotype is characterized by structural defects and is correlated with systolic dysfunction, th
Externí odkaz:
https://doaj.org/article/25849db75a5c4b46ae7f78d734102676
Autor:
Heidi Budde, Roua Hassoun, Melina Tangos, Saltanat Zhazykbayeva, Melissa Herwig, Marharyta Varatnitskaya, Marcel Sieme, Simin Delalat, Innas Sultana, Detmar Kolijn, Kamilla Gömöri, Muhammad Jarkas, Mária Lódi, Kornelia Jaquet, Árpád Kovács, Hans Georg Mannherz, Vasco Sequeira, Andreas Mügge, Lars I. Leichert, Samuel Sossalla, Nazha Hamdani
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1134 (2021)
Oxidative stress is defined as an imbalance between the antioxidant defense system and the production of reactive oxygen species (ROS). At low levels, ROS are involved in the regulation of redox signaling for cell protection. However, upon chronical
Externí odkaz:
https://doaj.org/article/5a64d6c759cd4774ad0e5804a10b5de2
Autor:
Viktor Bánhegyi, Attila Enyedi, Gábor Áron Fülöp, Attila Oláh, Ivetta Mányiné Siket, Csongor Váradi, Klaudia Bottyán, Mária Lódi, Alexandra Csongrádi, Azeem J. Umar, Miklós Fagyas, Dániel Czuriga, István Édes, Miklós Pólos, Béla Merkely, Zoltán Csanádi, Zoltán Papp, Gábor Szabó, Tamás Radovits, István Takács, Attila Tóth
Publikováno v:
Cells, Vol 10, Iss 7, p 1708 (2021)
Objective: Inhibitors of the angiotensin converting enzyme (ACE) are the primarily chosen drugs to treat heart failure and hypertension. Moreover, an imbalance in tissue ACE/ACE2 activity is implicated in COVID-19. In the present study, we tested the
Externí odkaz:
https://doaj.org/article/533fd267c0a748e98c7b9988dae01145
Autor:
Hans Georg Mannherz, Vasco Sequeira, Heidi Budde, Marina Skrygan, Saltanat Zhazykbayeva, Árpád Kovács, Nusratul Mostafi, Stefanie Bruckmüller, Thilo Gambichler, Roua Hassoun, Muhammad Jarkas, Marcel Sieme, Steffen Pabel, Andreas Mügge, Nazha Hamdani, Kornelia Jaquet, Mária Lódi, Cris dos Remedios, Samuel Sossalla, Simin Delalat, Melissa Herwig, Melina Tangos, Kamilla Gömöri
Publikováno v:
International Journal of Cardiology. 344:160-169
Hypertrophic cardiomyopathy (HCM) is a complex myocardial disorder with no well-established disease-modifying therapy so far. Our study aimed to investigate how autophagy, oxidative stress, inflammation, stress signalling pathways, and apoptosis are
Autor:
Michael M. Kreusser, Harald F. Langer, Paul Steendijk, Shahrooz Ghaderi, Vasco Sequeira, Niels Voigt, Gert-Hinrich Reil, Lars S. Maier, Mária Lódi, Zoltán Papp, Mark T. Waddingham, Dominik Linz, Mathias Hohl, Jan-Christian Reil, Dobromir Dobrev, Melissa Herwig, Andreas Mügge, Árpád Kovács, Nazha Hamdani, Svenja Meyhöfer
Publikováno v:
Journal of Physiology, 598(15), 3129-3153. WILEY
J Physiol
J Physiol
Key points The Anrep effect represents the alteration of left ventricular (LV) contractility to acutely enhanced afterload in a few seconds, thereby preserving stroke volume (SV) at constant preload. As a result of the missing preload stretch in our