Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Márcia N.M. Alves"'
Autor:
Jader S. Cruz, Silvia Guatimosim, Márcia N.M. Alves, Danilo Roman-Campos, Marco Fabrício Dias-Peixoto, Amanda B. Parreira, Pedro W.M. Almeida
Publikováno v:
International Journal of Sports Medicine. 38:949-953
We investigated the effects of palmitate, a high saturated fat, on Ca2+, action potential and reactive oxygen species dynamics in cardiomyocytes from untrained and trained mice. Male mice were subjected to moderate intensity exercise training on a tr
Autor:
Luciana Mitraud, Nivia M Santiago, Silvia Guatimosim, Marcos B. Melo, Itamar C. G. Jesus, Eduardo Nocchi, Leonardo Greco, Márcia N.M. Alves, Pedro W.M. Almeida, Maria José Campagnole-Santos, Rodrigo Ribeiro Resende, Robson A.S. Santos, Ricardo F. Lima, Mariana Gavioli, Amanda B. Parreira
Publikováno v:
Hypertension. 66:389-395
Mineralocorticoids have been implicated in the pathogenesis of diastolic heart failure. On the contrary, angiotensin (Ang)-(1–7) has emerged as a potential strategy for treatment of cardiac dysfunction induced by excessive mineralocorticoid recepto
Autor:
Robson A.S. Santos, Natalia Alenina, Amanda B. Parreira, Sasha Luísa de Azevedo Nunes, Danilo Roman-Campos, Michael Bader, Aline Lara, Márcia N.M. Alves, Jader S. Cruz, Rodrigo R. Resende, Sandra Lauton Santos, Enéas Ricardo de Morais Gomes, Cibele Rocha Resende, Silvia Guatimosim, Pedro W.M. Almeida, Ricardo F. Lima, Mariana Gavioli, Antonio Nei Santana Gondim
Publikováno v:
Hypertension. 61:425-430
High serum levels of aldosterone have been linked to the development of cardiac disease. In contrast, angiotensin (Ang)-(1-7) was extensively shown to possess cardioprotective effects, including the attenuation of cardiac dysfunction induced by exces
Autor:
M. Fatima Leite, Alvair P. Almeida, Dawidson Assis Gomes, Carla J. Aguiar, Vanessa L. Andrade, Rodrigo R. Resende, Márcia N.M. Alves, Ana Cristina do Nascimento Pinheiro, Enéas Ricardo de Morais Gomes, Silvia Guatimosim, Alfredo M. Goes, Marina Ladeira
Publikováno v:
Cell Calcium. 47:37-46
GPR91 is an orphan G-protein-coupled receptor (GPCR) that has been characterized as a receptor for succinate, a citric acid cycle intermediate, in several tissues. In the heart, the role of succinate is unknown. We now report that rat ventricular car
Autor:
Márcia N.M. Alves, Pedro W.M. Almeida, Antônio José Natali, Silvia Guatimosim, Aline M.A. Souza, Clóvis Andrade Neves, Marcelo Eustáquio Silva, Marcia Flores da Silva, Leonardo Bonato Felix, Rômulo Dias Novaes, Deoclécio A. Chianca, Arlete Rita Penitente
Publikováno v:
Cells, tissues, organs. 198(4)
Protein restriction (PR) is associated with cardiovascular diseases. The purpose of this study was to investigate the effects on single ventricular cardiomyocyte contractile function of a short-term PR after weaning. Male Fischer rats that were 28 da
Autor:
Ricardo F. Lima, Vânia F. Prado, Andrea Cristina Gomes Pires, Silvia Guatimosim, Márcia N.M. Alves, Michael K. Richardson, Enéas Ricardo de Morais Gomes, Alvair P. Almeida, Marta N. Cordeiro, Denis D. Damasceno, Marco A. M. Prado, Christopher Kushmerick, Alexandre Barbosa Andrade, Anderson J. Ferreira, Marcus Vinicius Gomez
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 57(2)
In this study, we evaluated the effects of PhKv, a 4584 Da peptide isolated from the spider Phoneutria nigriventer venom, in the isolated rat heart and in isolated ventricular myocytes. Ventricular arrhythmias were induced by occlusion of the left an
Autor:
Márcia N.M. Alves, Michael Bader, Carlos H. Castro, Gregory T. Kitten, Cristiane R. Fagundes-Moura, Silvia Guatimosim, Marco Fabrício Dias-Peixoto, Enéas Ricardo de Morais Gomes, Anderson J. Ferreira, Timothy L. Reudelhuber, Brit Rentzsch, Pedro W.M. Almeida, Alexandre M. Guimarães, Elisandra Gava, Robson A.S. Santos, Alvair P. Almeida
Publikováno v:
Therapeutic advances in cardiovascular disease. 4(2)
Objective: It has been shown that Ang-(1-7) has cardioprotective actions. To directly investigate the effects of Ang-(1-7) specifically in the heart, we generated and characterized transgenic (TG) rats which express an Ang-(1-7)-producing fusion prot
Autor:
Kristine Skårdal, Charlotte Bjork Ingul, Harald E. M. Hansen, Marte Thuen, Morten A. Høydal, Anne Berit Johnsen, Ulrik Wisløff, Natale Rolim, Tomas Stølen, Guri Kaurstad, Márcia N.M. Alves
Publikováno v:
Biophysical Journal. 98(3)
Diabetic patients have greater risk of developing congestive heart failure (HF) after myocardium infarction (MI). Exercise training is an effective strategy for preventing the development of cardiomyopathies and the incidence of cardiovascular morbid
Autor:
Márcia N.M. Alves, Leonardo Greco, Pedro W.M. Almeida, Silvia Guatimosim, Natalia Alenina, Beatrix Fauler, Marco Fabrício Dias-Peixoto, Michael Bader, Robson A.S. Santos, Enéas Ricardo de Morais Gomes, Mariana Rosa
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 52(3)
Recently there has been growing evidence suggesting that beneficial effects of angiotensin-(1-7) [Ang-(1-7)] in the heart are mediated by its receptor Mas. However, the signaling pathways involved in these effects in cardiomyocytes are unknown. Here,
Autor:
Márcia N.M. Alves, Leonardo Y. Tanaka, Kaleizu T. Rosa, Eduardo M. Krieger, Silvia Guatimosim, Luiz Roberto Grassmann Bechara, Alessandra Medeiros, Marcele A. Coelho, Andrea Somolanji Vanzelli, Julio C.B. Ferreira, Maria C. Irigoyen, Jan B. Bartholomeu, P. R. Ramires, Patricia Chakur Brum, Carlos Eduardo Negrão, Natale Pinheiro Lage Rolim, Katt Coelho Mattos, José Eduardo Krieger
Publikováno v:
Journal of molecular and cellular cardiology. 45(2)
beta-blockers, as class, improve cardiac function and survival in heart failure (HF). However, the molecular mechanisms underlying these beneficial effects remain elusive. In the present study, metoprolol and carvedilol were used in doses that displa