Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Márcia C. Neves"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/55bccdd281d143f698c55a02674f0e64
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The emergence of biopharmaceuticals, including proteins, nucleic acids, peptides, and vaccines, revolutionized the medical field, contributing to significant advances in the prophylaxis and treatment of chronic and life-threatening diseases. However,
Externí odkaz:
https://doaj.org/article/bbd67977d53f4d72b90040d1fb84399a
Autor:
Mafalda R. Almeida, Raquel O. Cristóvão, Maria A. Barros, João C. F. Nunes, Rui A. R. Boaventura, José M. Loureiro, Joaquim L. Faria, Márcia C. Neves, Mara G. Freire, Valéria C. Santos-Ebinuma, Ana P. M. Tavares, Cláudia G. Silva
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract l-asparaginase (ASNase, EC 3.5.1.1) is an enzyme that catalyzes the l-asparagine hydrolysis into l-aspartic acid and ammonia, being mainly applied in pharmaceutical and food industries. However, some disadvantages are associated with its fre
Externí odkaz:
https://doaj.org/article/3f5da1c099de4158876e8d4b70b363fa
Autor:
João C. F. Nunes, Raquel O. Cristóvão, Valéria C. Santos-Ebinuma, Joaquim L. Faria, Cláudia G. Silva, Márcia C. Neves, Mara G. Freire, Ana P. M. Tavares
Publikováno v:
Encyclopedia, Vol 1, Iss 3, Pp 848-858 (2021)
L-asparaginase (ASNase) is an aminohydrolase enzyme widely used in the pharmaceutical and food industries. Although currently its main applications are focused on the treatment of lymphoproliferative disorders such as acute lymphoblastic leukemia (AL
Externí odkaz:
https://doaj.org/article/980237c3f78f4394a984178fe4f02ea9
Autor:
Pankaj Bharmoria, Meena Bisht, Maria C. Gomes, Margarida Martins, Márcia C. Neves, João F. Mano, Igor Bdikin, João A. P. Coutinho, Sónia P. M. Ventura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The sustainable cellular delivery of the pleiotropic drug curcumin encounters drawbacks related to its fast autoxidation at the physiological pH, cytotoxicity of delivery vehicles and poor cellular uptake. A biomaterial compatible with curcu
Externí odkaz:
https://doaj.org/article/091b78d2bf0d4836be044f6647df2f0f
Autor:
Pankaj Bharmoria, Dibyendu Mondal, Matheus M. Pereira, Márcia C. Neves, Mafalda R. Almeida, Maria C. Gomes, João F. Mano, Igor Bdikin, Rute A. S. Ferreira, João A. P. Coutinho, Mara G. Freire
Publikováno v:
Communications Materials, Vol 1, Iss 1, Pp 1-13 (2020)
The applicability of protein fibrils as functional biomaterials is limited due to low scalability of production process, slow kinetics, and requirement of expensive purified proteins. Here, instantaneous production of protein fibrils from egg white p
Externí odkaz:
https://doaj.org/article/cd3c6ea4b0464b06b9d1ef9949d0e930
Autor:
Cátia Venâncio, Bruna Monteiro, Rafael Francisco, Márcia C. Neves, Mara G. Freire, Ana Catarina A. Sousa, Isabel Lopes
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 101 (2022)
Given the growing number of cancer diseases, new cytostatic drugs are approved daily, often with concomitant development, or refinement of some of these drugs aimed at decreasing patient discomfort during the administration period (e.g., prodrugs). C
Externí odkaz:
https://doaj.org/article/fbb4a8181d82466ca97de155c084c321
Autor:
Raquel O. Cristóvão, Rita A. M. Barros, João G. Pinho, Lília S. Teixeira, Márcia C. Neves, Mara G. Freire, Joaquim L. Faria, Valéria C. Santos-Ebinuma, Ana P. M. Tavares, Cláudia G. Silva
Publikováno v:
Applied Sciences, Vol 12, Iss 17, p 8924 (2022)
L-asparaginase (ASNase, EC 3.5.1.1) is an amidohydrolase enzyme known for its anti-cancer properties, with an ever-increasing commercial value. Immobilization has been studied to improve the enzyme’s efficiency, enabling its recovery and reuse, enh
Externí odkaz:
https://doaj.org/article/9dc09d700b16405f89a4253cb9269d9d
Autor:
Rita A. M. Barros, Raquel O. Cristóvão, Sónia A. C. Carabineiro, Márcia C. Neves, Mara G. Freire, Joaquim L. Faria, Valéria C. Santos-Ebinuma, Ana P. M. Tavares, Cláudia G. Silva
Publikováno v:
BioTech, Vol 11, Iss 2, p 10 (2022)
L-asparaginase (ASNase) is an aminohydrolase currently used in the pharmaceutical and food industries. Enzyme immobilization is an exciting option for both applications, allowing for a more straightforward recovery and increased stability. High surfa
Externí odkaz:
https://doaj.org/article/878de2ac7edf4f3eb9bd5df1ae83e4ef
Publikováno v:
Molecules, Vol 27, Iss 5, p 1618 (2022)
Liquid chromatography plays a central role in biomanufacturing, and, apart from its use as a preparative purification strategy, either in biopharmaceuticals or in fine chemicals industries, it is also very useful as an analytical tool for monitoring,
Externí odkaz:
https://doaj.org/article/fe869a3bdbb145e0b8d65de9996828c1