Zobrazeno 1 - 10
of 1 277
pro vyhledávání: '"M, van der Flier"'
Autor:
Aniek M. van Gils, Antti Tolonen, Argonde C. van Harten, Sinthujah Vigneswaran, Frederik Barkhof, Leonie N. C. Visser, Juha Koikkalainen, Sanna-Kaisa Herukka, Steen Gregers Hasselbalch, Patrizia Mecocci, Anne M. Remes, Hilkka Soininen, Afina W. Lemstra, Charlotte E. Teunissen, Linus Jönsson, Jyrki Lötjönen, Wiesje M. van der Flier, Hanneke F. M. Rhodius-Meester
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background The increasing prevalence of dementia and the introduction of disease-modifying therapies (DMTs) highlight the need for efficient diagnostic pathways in memory clinics. We present a data-driven approach to efficiently guide stepwi
Externí odkaz:
https://doaj.org/article/a2890bad16974239a6f09dd399617f9d
Autor:
Marta del Campo, Carlos Quesada, Lisa Vermunt, Carel F. W. Peeters, Yanaika S. Hok-A-Hin, Calvin Trieu, Anouk den Braber, Inge M. W. Verberk, Pieter J. Visser, Betty M. Tijms, Wiesje M. van der Flier, Charlotte E. Teunissen
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-5 (2024)
Abstract This preclinical AD CSF proteome study identified a panel of 12-CSF markers detecting amyloid positivity and clinical progression to AD with high accuracy; some of these CSF proteins related to immune function, neurotrophic processes, energy
Externí odkaz:
https://doaj.org/article/02bf197ce2e0447abfb8c9d7bd7ba96c
Autor:
Marie R. Vermeiren, Joost Somsen, Gert Luurtsema, Fransje E. Reesink, Nicolaas A. Verwey, Liesbeth Hempenius, Nelleke Tolboom, Geert Jan Biessels, J. Matthijs Biesbroek, Meike W. Vernooij, Sophie E. M. Veldhuijzen van Zanten, Harro Seelaar, Emma M. Coomans, Charlotte E. Teunissen, Afina W. Lemstra, Argonde C. van Harten, Leonie N. C. Visser, Wiesje M. van der Flier, Elsmarieke van de Giessen, Rik Ossenkoppele
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Tau-PET is a diagnostic tool with high sensitivity and specificity for discriminating Alzheimer’s disease (AD) dementia from other neurodegenerative disorders in well-controlled research environments. The role of tau-PET in real
Externí odkaz:
https://doaj.org/article/d3a59bc2cf6d4922a76611eb0bd5f947
Autor:
Lisa Le Scouarnec, Vincent Bouteloup, Pieter J van der Veere, Wiesje M van der Flier, Charlotte E Teunissen, Inge M W Verberk, Vincent Planche, Geneviève Chêne, Carole Dufouil
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background The accumulation of amyloid-β (Aβ) peptide in the brain is a hallmark of Alzheimer’s disease (AD), occurring years before symptom onset. Current methods for quantifying in vivo amyloid load involve invasive or costly procedure
Externí odkaz:
https://doaj.org/article/66a49c47182249c0ac9ee72e102c4862
Autor:
Ilse Bader, Colin Groot, H. Stevie Tan, Jean-Marie A. Milongo, Jurre den Haan, Inge M. W. Verberk, Keir Yong, Julie Orellina, Shannon Campbell, David Wilson, Argonde C. van Harten, Pauline H. B. Kok, Wiesje M. van der Flier, Yolande A. L. Pijnenburg, Frederik Barkhof, Elsmarieke van de Giessen, Charlotte E. Teunissen, Femke H. Bouwman, Rik Ossenkoppele
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Alzheimer’s disease (AD) is a common, complex and multifactorial disease that may require screening across multiple routes of referral to enable early detection and subsequent future implementation of tailored interventions. Blo
Externí odkaz:
https://doaj.org/article/80e39a0fdb1b42279ca2d571671cea81
Autor:
Rosanne L. van den Berg, Casper de Boer, Marissa D. Zwan, Roos J. Jutten, Mariska van Liere, Marie-Christine A.B.J. van de Glind, Mark A. Dubbelman, Lisa Marie Schlüter, Argonde C. van Harten, Charlotte E. Teunissen, Elsmarieke van de Giessen, Frederik Barkhof, Lyduine E. Collij, Jessica Robin, William Simpson, John E Harrison, Wiesje M. van der Flier, Sietske A.M. Sikkes
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Digital speech assessment has potential relevance in the earliest, preclinical stages of Alzheimer’s disease (AD). We evaluated the feasibility, test-retest reliability, and association with AD-related amyloid-beta (Aβ) patholo
Externí odkaz:
https://doaj.org/article/75ea7ee6329e4654a1896779b7cc2a38
Autor:
Kay Deckers, Marissa D. Zwan, Lion M. Soons, Lisa Waterink, Sonja Beers, Sofie van Houdt, Berrit Stiensma, Judy Z. Kwant, Sophie C. P. M. Wimmers, Rachel A. M. Heutz, Jurgen A. H. R. Claassen, Joukje M. Oosterman, Rianne A. A. de Heus, Ondine van de Rest, Yannick Vermeiren, Richard C. Oude Voshaar, Nynke Smidt, Laus M. Broersen, Sietske A. M. Sikkes, Esther Aarts, MOCIA consortium, FINGER-NL consortium, Sebastian Köhler, Wiesje M. van der Flier
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Evidence on the effectiveness of multidomain lifestyle interventions to prevent cognitive decline in older people without dementia is mixed. Embedded in the World-Wide FINGERS initiative, FINGER-NL aims to investigate the effectiv
Externí odkaz:
https://doaj.org/article/464762dfc60d4fd8aa0c690acaa338ce
Autor:
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodriguez, Inge M. W. Verberk, Sanne G. S. Verberk, Danielle W. R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff, Dorine Wouters, Jan Van den Bossche, Juan J. Garcia-Vallejo, Afina W. Lemstra, Maarten E. Witte, Wiesje M. van der Flier, Charlotte E. Teunissen, Helga E. de Vries
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract Background Alzheimer’s disease (AD) is the most frequent cause of dementia. Recent evidence suggests the involvement of peripheral immune cells in the disease, but the underlying mechanisms remain unclear. Methods We comprehensively mapped
Externí odkaz:
https://doaj.org/article/bbeaac8f21914591a0b29202e34aed6d
Autor:
Aniek M. van Gils, Hanneke F. M. Rhodius-Meester, Dédé Handgraaf, Heleen M. A. Hendriksen, Astrid van Strien, Niki Schoonenboom, Annemieke Schipper, Mariska Kleijer, Annemiek Griffioen, Majon Muller, Antti Tolonen, Jyrki Lötjönen, Wiesje M. van der Flier, Leonie N. C. Visser
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Both memory clinic professionals and patients see value in digital tools, yet these hardly find their way to clinical practice. We explored the usability of a digital tool to support the diagnostic work-up in daily memory clinic p
Externí odkaz:
https://doaj.org/article/f0bec7b8e71a414fbd5ad2e4051e493a
Autor:
Lisa Waterink, Larissa A. Masselink, Sven J. van der Lee, Leonie N. C. Visser, Solange Cleutjens, Jetske van der Schaar, Argonde C. van Harten, Philip Scheltens, Sietske A. M. Sikkes, Wiesje M. van der Flier, Marissa D. Zwan
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Apolipoprotein-E (APOE) genetic testing for Alzheimer’s disease is becoming more important as clinical trials are increasingly targeting individuals carrying APOE-ε4 alleles. Little is known about the interest in finding out on
Externí odkaz:
https://doaj.org/article/42b3b0c2cdb74855a9ee7e49bcdf3ba0