Zobrazeno 1 - 10
of 1 466
pro vyhledávání: '"M, Wolter"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10103 (2024)
Evidence suggests that angiotensin-converting enzyme inhibitors (ACEIs) may increase metabolic rate by promoting thermogenesis, potentially through enhanced fat oxidation and improved insulin. More research is, however, needed to understand this intr
Externí odkaz:
https://doaj.org/article/23903e01100847858891652530639e1d
Autor:
Lei Xing, Jeremy M. Simon, Travis S. Ptacek, Jason J. Yi, Lipin Loo, Hanqian Mao, Justin M. Wolter, Eric S. McCoy, Smita R. Paranjape, Bonnie Taylor-Blake, Mark J. Zylka
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112706- (2023)
Summary: The E3 ubiquitin ligase Ube3a is biallelically expressed in neural progenitors and glial cells, suggesting that UBE3A gain-of-function mutations might cause neurodevelopmental disorders irrespective of parent of origin. Here, we engineered a
Externí odkaz:
https://doaj.org/article/e51c03b71c704840a187f7c84c88daee
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 7, Pp 441-453 (2022)
Abstract Numerous autism spectrum disorder (ASD) risk genes are associated with Wnt signaling, suggesting that brain development may be especially sensitive to genetic perturbation of this pathway. Additionally, valproic acid, which modulates Wnt sig
Externí odkaz:
https://doaj.org/article/e60960da278b469e9b674b809db80ea0
Autor:
Michael J Lafferty, Nil Aygün, Niyanta K Patel, Oleh Krupa, Dan Liang, Justin M Wolter, Daniel H Geschwind, Luis de la Torre-Ubieta, Jason L Stein
Publikováno v:
eLife, Vol 12 (2023)
Expression quantitative trait loci (eQTL) data have proven important for linking non-coding loci to protein-coding genes. But eQTL studies rarely measure microRNAs (miRNAs), small non-coding RNAs known to play a role in human brain development and ne
Externí odkaz:
https://doaj.org/article/879e6be524424938b8ce9bf78a43c091
Autor:
A.C. Nickel, D. Picard, N. Qin, M. Wolter, K. Kaulich, M. Hewera, D. Pauck, V. Marquardt, G. Torga, S. Muhammad, W. Zhang, O. Schnell, H.-J. Steiger, D. Hänggi, E. Fritsche, N.-G. Her, D.-H. Nam, M.S. Carro, M. Remke, G. Reifenberger, U.D. Kahlert
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112278- (2021)
The utility of patient-derived tumor cell lines as experimental models for glioblastoma has been challenged by limited representation of the in vivo tumor biology and low clinical translatability. Here, we report on longitudinal epigenetic and transc
Externí odkaz:
https://doaj.org/article/ef35d0cf9fa94f5e85dbd336eabcbef8
Autor:
Virginia Paton, Gracie Lieberman, Melody A. Cobleigh, Debasish Tripathy, Nicholas J. Robert, Charles L. Vogel, Louis Fehrenbacher, Janet M. Wolter, Steven Shak, Susy Scholl, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 41:1501-1510
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive form of the disease. Efficacy and safety of recombinant humanized anti-HER2 monoclonal antibody as a single agent was evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded08dd9f167476ed2efc2074b46088b
https://doi.org/10.1200/jco.22.02510
https://doi.org/10.1200/jco.22.02510
Akademický článek
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Akademický článek
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Autor:
Nana Matoba, Brandon D Le, Jordan M Valone, Justin M Wolter, Jessica Mory, Dan Liang, Nil Aygün, K Alaine Broadaway, Marielle L Bond, Karen L Mohlke, Mark J Zylka, Michael I Love, Jason L Stein
Publikováno v:
bioRxiv
Gene regulatory effects in bulk-post mortem brain tissues are undetected at many non-coding brain trait-associated loci. We hypothesized that context-specific genetic variant function during stimulation of a developmental signaling pathway would expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608adc1109dea2fd41f0b7999834d954
https://europepmc.org/articles/PMC9934631/
https://europepmc.org/articles/PMC9934631/
Autor:
Michael J. Lafferty, Nil Aygün, Niyanta K. Patel, Oleh Krupa, Dan Liang, Justin M. Wolter, Daniel H. Geschwind, Luis de la Torre-Ubieta, Jason L. Stein
Expression quantitative trait loci (eQTL) data have proven important for linking non-coding loci to protein-coding genes. But eQTL studies rarely measure microRNAs (miRNAs), small non-coding RNAs known to play a role in human brain development and ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc6f89911037a7eb5b30d31d3d7629c