Zobrazeno 1 - 10
of 646
pro vyhledávání: '"M, Wetzler"'
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108749- (2024)
Summary: Generating large-scale, high-fidelity sequencing data is challenging and, furthermore, not much has been done to characterize adjuvants’ effects at the repertoire level. Thus, we introduced an IgSeq pipeline that standardized library prep
Externí odkaz:
https://doaj.org/article/5594b508a7ee46cdaaeae4cedc008260
Autor:
Shea K. Roe, Brian Felter, Bo Zheng, Sanjay Ram, Lee M. Wetzler, Eric Garges, Tianmou Zhu, Caroline A. Genco, Paola Massari
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1846 (2023)
Gonorrhea, a sexually transmitted disease caused by Neisseria gonorrhoeae, poses a significant global public health threat. Infection in women can be asymptomatic and may result in severe reproductive complications. Escalating antibiotic resistance u
Externí odkaz:
https://doaj.org/article/80dc3c05003f447cb5bb993ac31ed948
Autor:
Pranay Sinha, Anahita Mostaghim, Catherine G. Bielick, Angela McLaughlin, Davidson H. Hamer, Lee M. Wetzler, Nahid Bhadelia, Maura A. Fagan, Benjamin P. Linas, Sabrina A. Assoumou, Michael H. Ieong, Nina H. Lin, Ellen R. Cooper, Karrine D. Brade, Laura F. White, Tamar F. Barlam, Manish Sagar
Publikováno v:
International Journal of Infectious Diseases, Vol 99, Iss , Pp 28-33 (2020)
Objective: The aim of this observational study was to determine the optimal timing of interleukin-6 receptor inhibitor (IL6ri) administration for coronavirus disease 2019 (COVID-19). Methods: Patients with COVID-19 were given an IL6ri (sarilumab or t
Externí odkaz:
https://doaj.org/article/1c57d40345b4490a90bde0fbf6a4c1b1
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 11, Pp 2778-2781 (2019)
Our laboratory has focused on Porin B (PorB), an outer membrane protein from Neisseria meningitidis and TLR2 ligand-based adjuvant, to characterize specific molecular and cellular pathways involved in improved immune responses induced by vaccine adju
Externí odkaz:
https://doaj.org/article/e22089fa14b64f889812ad76cadad946
Autor:
Christina Lisk, Rachel Yuen, Jeff Kuniholm, Danielle Antos, Michael L. Reiser, Lee M. Wetzler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Vaccines have played a pivotal role in improving public health, however, many infectious diseases lack an effective vaccine. Controlling the spread of infectious diseases requires continuing studies to develop new and improved vaccines. Our laborator
Externí odkaz:
https://doaj.org/article/df8bb2dc7ce4411596dfe98e3699bffb
Autor:
Christina Lisk, Rachel Yuen, Jeff Kuniholm, Danielle Antos, Michael L. Reiser, Lee M. Wetzler
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Vaccines are arguably one of the greatest advancements in modern medicine. Subunit vaccines comprise the majority of current preparations and consist of two main components—antigen and adjuvant. The antigen is a small molecule against which the vac
Externí odkaz:
https://doaj.org/article/0d3f6b930f3c49909c9527e595c6cdf5
Autor:
Ian P. Francis, Epshita A. Islam, Adam C. Gower, Yazdani B. Shaik-Dasthagirisaheb, Scott D. Gray-Owen, Lee M. Wetzler
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-19 (2018)
Abstract Background The emergence of fully antimicrobial resistant Neisseria gonorrhoeae has led global public health agencies to identify a critical need for next generation anti-gonococcal pharmaceuticals. The development and success of these compo
Externí odkaz:
https://doaj.org/article/e83a46da26fb44d691f85bef4e372ada
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract TOLL-like receptor (TLR) ligands activate both innate and adaptive immune cells, while modulating the cellular immune response. The outer membrane protein (OMP) from Neisseria meninigitidis, PorB, is a naturally occurring TLR2 ligand and fun
Externí odkaz:
https://doaj.org/article/819a8f1a2e204e349e1f1b4a7c394570
Autor:
Michael L. Reiser, Danielle Antos, Jeff Kuniholm, Lee M. Wetzler, Christina Lisk, Rachel Yuen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Vaccines have played a pivotal role in improving public health, however, many infectious diseases lack an effective vaccine. Controlling the spread of infectious diseases requires continuing studies to develop new and improved vaccines. Our laborator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89231d9cb6e1b6f1550bcfa4cd7dda8
https://doi.org/10.3389/fimmu.2021.624197
https://doi.org/10.3389/fimmu.2021.624197
Publikováno v:
Journal of Autonomous Vehicles and Systems. 1
This paper studies the time optimal paths of a mobile robot navigating in a planar environment containing an obstacle. The paper considers a point-mass robot that moves with bounded acceleration and limited turn-rate controls in the presence of an ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4508987efa5e09664059911de24d391e
https://doi.org/10.1115/1.4049834
https://doi.org/10.1115/1.4049834